These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

70 related articles for article (PubMed ID: 21051818)

  • 1. Bis[(1S)-1,4-azanediyl-1-(9-deazaadenin-9-yl)-1,4-dideoxy-5-methylsulfanyl-D-ribitol] tetrakis(hydrochloride) monohydrate: structure, DFT energy and ligand docking results of a potent methylthioadenosine phosphorylase inhibitor found in different molecular conformations.
    Gainsford GJ; Evans GB; Johnston KA; Seth M
    Acta Crystallogr C; 2010 Nov; 66(Pt 11):o527-30. PubMed ID: 21051818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
    Singh V; Shi W; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
    Biochemistry; 2004 Jan; 43(1):9-18. PubMed ID: 14705926
    [TBL] [Abstract][Full Text] [Related]  

  • 3. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
    Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
    Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
    Luić M; Koellner G; Yokomatsu T; Shibuya S; Bzowska A
    Acta Crystallogr D Biol Crystallogr; 2004 Aug; 60(Pt 8):1417-24. PubMed ID: 15272165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family.
    Gainsford GJ; Furneaux RH; Tyler PC; Sauve A; Shramm VL
    Acta Crystallogr C; 2010 Mar; 66(Pt 3):m65-8. PubMed ID: 20203397
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.
    Bzowska A; Koellner G; Wielgus-Kutrowska B; Stroh A; Raszewski G; Holý A; Steiner T; Frank J
    J Mol Biol; 2004 Sep; 342(3):1015-32. PubMed ID: 15342253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.
    Goeminne A; Berg M; McNaughton M; Bal G; Surpateanu G; Van der Veken P; De Prol S; Versées W; Steyaert J; Haemers A; Augustyns K
    Bioorg Med Chem; 2008 Jul; 16(14):6752-63. PubMed ID: 18571422
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM; Hayes JM; Tiraidis C; Zographos SE; Leonidas DD; Chrysina ED; Archontis G; Oikonomakos NG; Paul JV; Varghese B; Loganathan D
    Proteins; 2008 May; 71(3):1307-23. PubMed ID: 18041758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clindamycin hydrochloride monohydrate and its ethanol solvate.
    Ravikumar K; Sridhar B
    Acta Crystallogr C; 2010 Feb; 66(Pt 2):o97-100. PubMed ID: 20124689
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor.
    Pereira HM; Berdini V; Ferri MR; Cleasby A; Garratt RC
    Acta Trop; 2010 May; 114(2):97-102. PubMed ID: 20122887
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.
    Koellner G; Bzowska A; Wielgus-Kutrowska B; Luić M; Steiner T; Saenger W; Stepiński J
    J Mol Biol; 2002 Jan; 315(3):351-71. PubMed ID: 11786017
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases.
    Clinch K; Evans GB; Fleet GW; Furneaux RH; Johnson SW; Lenz DH; Mee SP; Rands PR; Schramm VL; Taylor Ringia EA; Tyler PC
    Org Biomol Chem; 2006 Mar; 4(6):1131-9. PubMed ID: 16525558
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
    Deng H; Lewandowicz A; Cahill SM; Furneaux RH; Tyler PC; Girvin ME; Callender RH; Schramm VL
    Biochemistry; 2004 Feb; 43(7):1980-7. PubMed ID: 14967038
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue.
    Pereira HM; Berdini V; Cleasby A; Garratt RC
    FEBS Lett; 2007 Oct; 581(26):5082-6. PubMed ID: 17927987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2,12-Dichloro-10,20-diphenyl-5,7,15,17-tetrahydro-6H,16H-dibenzo[d,l][1,9,2,6,10,14]dioxotetraazacyclohexadecine-6,16-dione dioxane solvate as a potential macrocyclic hexadentate ligand.
    Khrustalev VN; Komissarov EA; Kulikov OV
    Acta Crystallogr C; 2007 Jul; 63(Pt 7):o374-7. PubMed ID: 17609564
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural diversity in manganese, iron and cobalt complexes of the ditopic 1,2-bis(2,2'-bipyridyl-6-yl)ethyne ligand and observation of epoxidation and catalase activity of manganese compounds.
    Madhu V; Ekambaram B; Shimon LJ; Diskin Y; Leitus G; Neumann R
    Dalton Trans; 2010 Aug; 39(31):7266-75. PubMed ID: 20582360
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.
    Versées W; Barlow J; Steyaert J
    J Mol Biol; 2006 Jun; 359(2):331-46. PubMed ID: 16630632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based drug design: inhibitors of purine nucleoside phosphorylase.
    Montgomery JA
    Farmaco; 1993 Feb; 48(2):297-308. PubMed ID: 8494600
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
    Tebbe J; Bzowska A; Wielgus-Kutrowska B; Schröder W; Kazimierczuk Z; Shugar D; Saenger W; Koellner G
    J Mol Biol; 1999 Dec; 294(5):1239-55. PubMed ID: 10600382
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Determining the structural basis for specificity of ligands using crystallographic screening.
    de Azevedo WF; Canduri F; Basso LA; Palma MS; Santos DS
    Cell Biochem Biophys; 2006; 44(3):405-11. PubMed ID: 16679527
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.