These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 21052604)

  • 1. A QM/MM study of the phosphoryl transfer to the Kemptide substrate catalyzed by protein kinase A. The effect of the phosphorylation state of the protein on the mechanism.
    Montenegro M; Garcia-Viloca M; Lluch JM; González-Lafont A
    Phys Chem Chem Phys; 2011 Jan; 13(2):530-9. PubMed ID: 21052604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of the putative catalytic base in the phosphoryl transfer reaction in a protein kinase: first-principles calculations.
    Valiev M; Kawai R; Adams JA; Weare JH
    J Am Chem Soc; 2003 Aug; 125(33):9926-7. PubMed ID: 12914447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. How does the cAMP-dependent protein kinase catalyze the phosphorylation reaction: an ab initio QM/MM study.
    Cheng Y; Zhang Y; McCammon JA
    J Am Chem Soc; 2005 Feb; 127(5):1553-62. PubMed ID: 15686389
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A QM/MM study of Kemptide phosphorylation catalyzed by protein kinase A. The role of Asp166 as a general acid/base catalyst.
    Pérez-Gallegos A; Garcia-Viloca M; González-Lafont À; Lluch JM
    Phys Chem Chem Phys; 2015 Feb; 17(5):3497-511. PubMed ID: 25535906
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Influence of the enzyme phosphorylation state and the substrate on PKA enzyme dynamics.
    Montenegro M; Masgrau L; González-Lafont A; Lluch JM; Garcia-Viloca M
    Biophys Chem; 2012 Feb; 161():17-28. PubMed ID: 22154087
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An ATP-linked structural change in protein kinase A precedes phosphoryl transfer under physiological magnesium concentrations.
    Shaffer J; Adams JA
    Biochemistry; 1999 Apr; 38(17):5572-81. PubMed ID: 10220345
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insights into the phosphoryl-transfer mechanism of cAMP-dependent protein kinase from quantum chemical calculations and molecular dynamics simulations.
    Díaz N; Field MJ
    J Am Chem Soc; 2004 Jan; 126(2):529-42. PubMed ID: 14719950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physical nature of intermolecular interactions within cAMP-dependent protein kinase active site: differential transition state stabilization in phosphoryl transfer reaction.
    Szarek P; Dyguda-Kazimierowicz E; Tachibana A; Sokalski WA
    J Phys Chem B; 2008 Sep; 112(37):11819-26. PubMed ID: 18720966
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Understanding how cAMP-dependent protein kinase can catalyze phosphoryl transfer in the presence of Ca
    Pérez-Gallegos A; Garcia-Viloca M; González-Lafont À; Lluch JM
    Phys Chem Chem Phys; 2017 Apr; 19(16):10377-10394. PubMed ID: 28379230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A QM/MM study of the associative mechanism for the phosphorylation reaction catalyzed by protein kinase A and its D166A mutant.
    Pérez-Gallegos A; Garcia-Viloca M; González-Lafont À; Lluch JM
    J Comput Aided Mol Des; 2014 Nov; 28(11):1077-91. PubMed ID: 25129483
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Is there a catalytic base in the active site of cAMP-dependent protein kinase?
    Zhou J; Adams JA
    Biochemistry; 1997 Mar; 36(10):2977-84. PubMed ID: 9062128
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for an internal entropy contribution to phosphoryl transfer: a study of domain closure, backbone flexibility, and the catalytic cycle of cAMP-dependent protein kinase.
    Li F; Gangal M; Juliano C; Gorfain E; Taylor SS; Johnson DA
    J Mol Biol; 2002 Jan; 315(3):459-69. PubMed ID: 11786025
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism-based design of a protein kinase inhibitor.
    Parang K; Till JH; Ablooglu AJ; Kohanski RA; Hubbard SR; Cole PA
    Nat Struct Biol; 2001 Jan; 8(1):37-41. PubMed ID: 11135668
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide-nucleoside conjugate AdcAhxArg6.
    Kuznetsov A; Uri A; Raidaru G; Järv J
    Bioorg Chem; 2004 Dec; 32(6):527-35. PubMed ID: 15530993
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a partially rate-determining step in the catalytic mechanism of cAMP-dependent protein kinase: a transient kinetic study using stopped-flow fluorescence spectroscopy.
    Lew J; Taylor SS; Adams JA
    Biochemistry; 1997 Jun; 36(22):6717-24. PubMed ID: 9184152
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Catalytic independent functions of a protein kinase as revealed by a kinase-dead mutant: study of the Lys72His mutant of cAMP-dependent kinase.
    Iyer GH; Garrod S; Woods VL; Taylor SS
    J Mol Biol; 2005 Sep; 351(5):1110-22. PubMed ID: 16054648
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques.
    Grant BD; Adams JA
    Biochemistry; 1996 Feb; 35(6):2022-9. PubMed ID: 8639687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p.
    Aubol BE; Nolen B; Shaffer J; Ghosh G; Adams JA
    Biochemistry; 2003 Nov; 42(44):12813-20. PubMed ID: 14596595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of the phosphoryl transfer mechanism of c-AMP dependent protein kinase (PKA) by penta-coodinate phosphoric transition state theory.
    Ni F; Li W; Li YM; Zhao YF
    Curr Protein Pept Sci; 2005 Oct; 6(5):437-42. PubMed ID: 16248795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the catalytic mechanism of the p21-activated protein kinase PAK2.
    Wu H; Zheng Y; Wang ZX
    Biochemistry; 2003 Feb; 42(4):1129-39. PubMed ID: 12549935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.