197 related articles for article (PubMed ID: 21053101)
21. Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC.
Tacchelly-Benites O; Wang Z; Yang E; Benchabane H; Tian A; Randall MP; Ahmed Y
PLoS Genet; 2018 Feb; 14(2):e1007178. PubMed ID: 29408853
[TBL] [Abstract][Full Text] [Related]
22. miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2.
Chen HY; Lang YD; Lin HN; Liu YR; Liao CC; Nana AW; Yen Y; Chen RH
Sci Rep; 2019 Jul; 9(1):9687. PubMed ID: 31273221
[TBL] [Abstract][Full Text] [Related]
23. Simultaneous destabilization of β-catenin and Ras via targeting of the axin-RGS domain as a potential therapeutic strategy for colorectal cancer.
Cha PH; Choi KY
BMB Rep; 2016 Sep; 49(9):455-6. PubMed ID: 27470214
[TBL] [Abstract][Full Text] [Related]
24. An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function.
Mazzoni SM; Petty EM; Stoffel EM; Fearon ER
Neoplasia; 2015 May; 17(5):463-72. PubMed ID: 26025668
[TBL] [Abstract][Full Text] [Related]
25. The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3beta and c-Jun/AP-1 signaling.
Le Floch N; Rivat C; De Wever O; Bruyneel E; Mareel M; Dale T; Gespach C
FASEB J; 2005 Jan; 19(1):144-6. PubMed ID: 15507471
[TBL] [Abstract][Full Text] [Related]
26. Genetic Polymorphisms in APC, DVL2, and AXIN1 Are Associated with Susceptibility, Advanced TNM Stage or Tumor Location in Colorectal Cancer.
Rosales-Reynoso MA; Saucedo-Sariñana AM; Contreras-Díaz KB; Márquez-González RM; Barros-Núñez P; Pineda-Razo TD; Marin-Contreras ME; Durán-Anguiano Ó; Gallegos-Arreola MP; Flores-Martínez SE; Sánchez-Corona J
Tohoku J Exp Med; 2019 Nov; 249(3):173-183. PubMed ID: 31723073
[TBL] [Abstract][Full Text] [Related]
27. Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta.
Martino-Echarri E; Brocardo MG; Mills KM; Henderson BR
PLoS One; 2016; 11(3):e0150484. PubMed ID: 26930278
[TBL] [Abstract][Full Text] [Related]
28. Axin PPI Networks: New Interacting Proteins and New Targets?
Song X; Cai W; Li L
Curr Top Med Chem; 2016; 16(30):3678-3690. PubMed ID: 27852210
[TBL] [Abstract][Full Text] [Related]
29. Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Anvarian Z; Nojima H; van Kappel EC; Madl T; Spit M; Viertler M; Jordens I; Low TY; van Scherpenzeel RC; Kuper I; Richter K; Heck AJ; Boelens R; Vincent JP; Rüdiger SG; Maurice MM
Nat Struct Mol Biol; 2016 Apr; 23(4):324-32. PubMed ID: 26974125
[TBL] [Abstract][Full Text] [Related]
30. Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation.
Cha PH; Cho YH; Lee SK; Lee J; Jeong WJ; Moon BS; Yun JH; Yang JS; Choi S; Yoon J; Kim HY; Kim MY; Kaduwal S; Lee W; Min do S; Kim H; Han G; Choi KY
Nat Chem Biol; 2016 Aug; 12(8):593-600. PubMed ID: 27294323
[TBL] [Abstract][Full Text] [Related]
31. A kinetic model to study the regulation of β-catenin, APC, and Axin in the human colonic crypt.
Emerick B; Schleiniger G; Boman BM
J Math Biol; 2017 Nov; 75(5):1171-1202. PubMed ID: 28271271
[TBL] [Abstract][Full Text] [Related]
32. Alteration in the Wnt/β-catenin signaling pathway in gastric neoplasias of fundic gland (chief cell predominant) type.
Hidaka Y; Mitomi H; Saito T; Takahashi M; Lee SY; Matsumoto K; Yao T; Watanabe S
Hum Pathol; 2013 Nov; 44(11):2438-48. PubMed ID: 24011952
[TBL] [Abstract][Full Text] [Related]
33. Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.
Jang MK; Mashima T; Seimiya H
Mol Cancer Ther; 2020 Mar; 19(3):765-776. PubMed ID: 31907221
[TBL] [Abstract][Full Text] [Related]
34. USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin.
Ji L; Lu B; Zamponi R; Charlat O; Aversa R; Yang Z; Sigoillot F; Zhu X; Hu T; Reece-Hoyes JS; Russ C; Michaud G; Tchorz JS; Jiang X; Cong F
Nat Commun; 2019 Sep; 10(1):4184. PubMed ID: 31519875
[TBL] [Abstract][Full Text] [Related]
35. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
Lau T; Chan E; Callow M; Waaler J; Boggs J; Blake RA; Magnuson S; Sambrone A; Schutten M; Firestein R; Machon O; Korinek V; Choo E; Diaz D; Merchant M; Polakis P; Holsworth DD; Krauss S; Costa M
Cancer Res; 2013 May; 73(10):3132-44. PubMed ID: 23539443
[TBL] [Abstract][Full Text] [Related]
36. The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions.
Gavagan M; Fagnan E; Speltz EB; Zalatan JG
Cell Syst; 2020 Jun; 10(6):515-525.e5. PubMed ID: 32553184
[TBL] [Abstract][Full Text] [Related]
37. Multivalent tumor suppressor adenomatous polyposis coli promotes Axin biomolecular condensate formation and efficient β-catenin degradation.
Li TM; Ren J; Husmann D; Coan JP; Gozani O; Chua KF
Sci Rep; 2020 Oct; 10(1):17425. PubMed ID: 33060621
[TBL] [Abstract][Full Text] [Related]
38. Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
Wang Z; Tacchelly-Benites O; Yang E; Thorne CA; Nojima H; Lee E; Ahmed Y
Genetics; 2016 May; 203(1):269-81. PubMed ID: 26975665
[TBL] [Abstract][Full Text] [Related]
39. Connecting COX-2 and Wnt in cancer.
Buchanan FG; DuBois RN
Cancer Cell; 2006 Jan; 9(1):6-8. PubMed ID: 16413466
[TBL] [Abstract][Full Text] [Related]
40. Colorectal cancer and genetic alterations in the Wnt pathway.
Segditsas S; Tomlinson I
Oncogene; 2006 Dec; 25(57):7531-7. PubMed ID: 17143297
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
