210 related articles for article (PubMed ID: 21054786)
1. Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1.
Welin M; Egeblad L; Johansson A; Stenmark P; Wang L; Flodin S; Nyman T; Trésaugues L; Kotenyova T; Johansson I; Eriksson S; Eklund H; Nordlund P
FEBS J; 2010 Dec; 277(23):4920-30. PubMed ID: 21054786
[TBL] [Abstract][Full Text] [Related]
2. A single amino acid substitution in the human and a bacterial hypoxanthine phosphoribosyltransferase modulates specificity for the binding of guanine.
Lee CC; Craig SP; Eakin AE
Biochemistry; 1998 Mar; 37(10):3491-8. PubMed ID: 9521670
[TBL] [Abstract][Full Text] [Related]
3. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
[TBL] [Abstract][Full Text] [Related]
4. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Munagala NR; Wang CC
Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
[TBL] [Abstract][Full Text] [Related]
5. Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
Xu Y; Eads J; Sacchettini JC; Grubmeyer C
Biochemistry; 1997 Mar; 36(12):3700-12. PubMed ID: 9132023
[TBL] [Abstract][Full Text] [Related]
6. Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.
Ullman B; Cyr N; Choi K; Jardim A
Int J Biochem Cell Biol; 2010 Feb; 42(2):253-62. PubMed ID: 19861168
[TBL] [Abstract][Full Text] [Related]
7. The role for glutamic acid at position 196 in human hypoxanthine phosphoribosyltransferase (HPRT) as investigated using site-directed mutagenesis.
Canyuk B; E-Wan A; Keawwijit W; Nualnoi T; Sirisatean L; Tansakul P; Tanthana C
Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):894-9. PubMed ID: 18600559
[TBL] [Abstract][Full Text] [Related]
8. Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
Xu Y; Grubmeyer C
Biochemistry; 1998 Mar; 37(12):4114-24. PubMed ID: 9521733
[TBL] [Abstract][Full Text] [Related]
9. The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.
Keough DT; Brereton IM; de Jersey J; Guddat LW
J Mol Biol; 2005 Aug; 351(1):170-81. PubMed ID: 15990111
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.
Somoza JR; Chin MS; Focia PJ; Wang CC; Fletterick RJ
Biochemistry; 1996 Jun; 35(22):7032-40. PubMed ID: 8679528
[TBL] [Abstract][Full Text] [Related]
11. Hypoxanthine-guanine phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv: cloning, expression, and biochemical characterization.
Biazus G; Schneider CZ; Palma MS; Basso LA; Santos DS
Protein Expr Purif; 2009 Aug; 66(2):185-90. PubMed ID: 19362594
[TBL] [Abstract][Full Text] [Related]
12. Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.
Guddat LW; Vos S; Martin JL; Keough DT; de Jersey J
Protein Sci; 2002 Jul; 11(7):1626-38. PubMed ID: 12070315
[TBL] [Abstract][Full Text] [Related]
13. [Cloning, expression and characterization of the hypoxanthine-guanine phosphoribosyltransferase mutants from T. tengcongensis].
You DL; Qu H; Chen Q; Xing Y; Gu XC; Luo M
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2003 Sep; 35(9):853-8. PubMed ID: 12958660
[TBL] [Abstract][Full Text] [Related]
14. Approaching the transition state in the crystal structure of a phosphoribosyltransferase.
Focia PJ; Craig SP; Eakin AE
Biochemistry; 1998 Dec; 37(49):17120-7. PubMed ID: 9860824
[TBL] [Abstract][Full Text] [Related]
15. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse.
Keebaugh AC; Mitchell HA; Gaval-Cruz M; Freeman KG; Edwards GL; Weinshenker D; Thomas JW
PLoS One; 2011; 6(7):e22381. PubMed ID: 21818316
[TBL] [Abstract][Full Text] [Related]
16. Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
Gogia S; Balaram H; Puranik M
Biochemistry; 2011 May; 50(19):4184-93. PubMed ID: 21486037
[TBL] [Abstract][Full Text] [Related]
17. Hypoxanthine phosphoribosyltransferase cDNA in gerbils (Meriones unguiculatus).
Mai Z; Horohov DW; Klei TR
Lab Anim Sci; 1998 Apr; 48(2):179-83. PubMed ID: 10090010
[TBL] [Abstract][Full Text] [Related]
18. Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
Munagala NR; Chin MS; Wang CC
Biochemistry; 1998 Mar; 37(12):4045-51. PubMed ID: 9521725
[TBL] [Abstract][Full Text] [Related]
19. A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity.
Raman J; Sumathy K; Anand RP; Balaram H
Arch Biochem Biophys; 2004 Jul; 427(1):116-22. PubMed ID: 15178494
[TBL] [Abstract][Full Text] [Related]
20. Comparative modeling of HGPRT enzyme of L. donovani and binding affinities of different analogs of GMP.
Ansari MY; Dikhit MR; Sahoo GC; Das P
Int J Biol Macromol; 2012 Apr; 50(3):637-49. PubMed ID: 22327112
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
