287 related articles for article (PubMed ID: 21062285)
1. Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1.
Brady OA; Meng P; Zheng Y; Mao Y; Hu F
J Neurochem; 2011 Jan; 116(2):248-59. PubMed ID: 21062285
[TBL] [Abstract][Full Text] [Related]
2. PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Lee S; Jeon YM; Cha SJ; Kim S; Kwon Y; Jo M; Jang YN; Lee S; Kim J; Kim SR; Lee KJ; Lee SB; Kim K; Kim HJ
Autophagy; 2020 Aug; 16(8):1396-1412. PubMed ID: 31690171
[TBL] [Abstract][Full Text] [Related]
3. Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system.
Wang X; Fan H; Ying Z; Li B; Wang H; Wang G
Neurosci Lett; 2010 Jan; 469(1):112-6. PubMed ID: 19944744
[TBL] [Abstract][Full Text] [Related]
4. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43.
King A; Maekawa S; Bodi I; Troakes C; Al-Sarraj S
Neuropathology; 2011 Jun; 31(3):239-49. PubMed ID: 21118398
[TBL] [Abstract][Full Text] [Related]
5. p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions.
Tanji K; Zhang HX; Mori F; Kakita A; Takahashi H; Wakabayashi K
J Neurosci Res; 2012 Oct; 90(10):2034-42. PubMed ID: 22674379
[TBL] [Abstract][Full Text] [Related]
6. p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS.
Al-Sarraj S; King A; Troakes C; Smith B; Maekawa S; Bodi I; Rogelj B; Al-Chalabi A; Hortobágyi T; Shaw CE
Acta Neuropathol; 2011 Dec; 122(6):691-702. PubMed ID: 22101323
[TBL] [Abstract][Full Text] [Related]
7. MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
Kim HC; Zhang Y; King PH; Lu L
J Neurochem; 2023 Mar; 164(5):643-657. PubMed ID: 36527420
[TBL] [Abstract][Full Text] [Related]
8. The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.
Chen HJ; Mitchell JC; Novoselov S; Miller J; Nishimura AL; Scotter EL; Vance CA; Cheetham ME; Shaw CE
Brain; 2016 May; 139(Pt 5):1417-32. PubMed ID: 26936937
[TBL] [Abstract][Full Text] [Related]
9. Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy.
Cascella R; Fani G; Capitini C; Rusmini P; Poletti A; Cecchi C; Chiti F
FASEB J; 2017 Dec; 31(12):5609-5624. PubMed ID: 28842427
[TBL] [Abstract][Full Text] [Related]
10. [The molecular mechanisms of intracellular TDP-43 aggregates].
Nonaka T; Arai T; Hasegawa M
Brain Nerve; 2009 Nov; 61(11):1292-300. PubMed ID: 19938686
[TBL] [Abstract][Full Text] [Related]
11. ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation.
Foster AD; Downing P; Figredo E; Polain N; Stott A; Layfield R; Rea SL
Mol Cell Neurosci; 2020 Oct; 108():103539. PubMed ID: 32835772
[TBL] [Abstract][Full Text] [Related]
12. Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1.
Kim SH; Shi Y; Hanson KA; Williams LM; Sakasai R; Bowler MJ; Tibbetts RS
J Biol Chem; 2009 Mar; 284(12):8083-92. PubMed ID: 19112176
[TBL] [Abstract][Full Text] [Related]
13. Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells.
Cicardi ME; Cristofani R; Rusmini P; Meroni M; Ferrari V; Vezzoli G; Tedesco B; Piccolella M; Messi E; Galbiati M; Boncoraglio A; Carra S; Crippa V; Poletti A
Sci Rep; 2018 Aug; 8(1):12390. PubMed ID: 30120266
[TBL] [Abstract][Full Text] [Related]
14. RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-43.
Takagi S; Iguchi Y; Katsuno M; Ishigaki S; Ikenaka K; Fujioka Y; Honda D; Niwa J; Tanaka F; Watanabe H; Adachi H; Sobue G
PLoS One; 2013; 8(6):e66966. PubMed ID: 23840565
[TBL] [Abstract][Full Text] [Related]
15. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord.
Braak H; Ludolph A; Thal DR; Del Tredici K
Acta Neuropathol; 2010 Jul; 120(1):67-74. PubMed ID: 20379728
[TBL] [Abstract][Full Text] [Related]
16. Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.
Nonaka T; Kametani F; Arai T; Akiyama H; Hasegawa M
Hum Mol Genet; 2009 Sep; 18(18):3353-64. PubMed ID: 19515851
[TBL] [Abstract][Full Text] [Related]
17. White matter lesions in the brain with frontotemporal lobar degeneration with motor neuron disease: TDP-43-immunopositive inclusions co-localize with p62, but not ubiquitin.
Hiji M; Takahashi T; Fukuba H; Yamashita H; Kohriyama T; Matsumoto M
Acta Neuropathol; 2008 Aug; 116(2):183-91. PubMed ID: 18584184
[TBL] [Abstract][Full Text] [Related]
18. Frontotemporal lobar degeneration with ubiquitinated tau-negative inclusions and additional alpha-synuclein pathology but also unusual cerebellar ubiquitinated p62-positive, TDP-43-negative inclusions.
King A; Al-Sarraj S; Shaw C
Neuropathology; 2009 Aug; 29(4):466-71. PubMed ID: 18715271
[TBL] [Abstract][Full Text] [Related]
19. C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43.
Nonaka T; Masuda-Suzukake M; Hosokawa M; Shimozawa A; Hirai S; Okado H; Hasegawa M
Hum Mol Genet; 2018 Aug; 27(15):2658-2670. PubMed ID: 29750243
[TBL] [Abstract][Full Text] [Related]
20. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.
Matsumoto G; Wada K; Okuno M; Kurosawa M; Nukina N
Mol Cell; 2011 Oct; 44(2):279-89. PubMed ID: 22017874
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]