BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 21075843)

  • 1. Inhibition of proprotein convertase SKI-1 blocks transcription of key extracellular matrix genes regulating osteoblastic mineralization.
    Gorski JP; Huffman NT; Chittur S; Midura RJ; Black C; Oxford J; Seidah NG
    J Biol Chem; 2011 Jan; 286(3):1836-49. PubMed ID: 21075843
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the prohormone convertase subtilisin-kexin isoenzyme-1 induces apoptosis in human melanoma cells.
    Weiß N; Stegemann A; Elsayed MAT; Schallreuter KU; Luger TA; Loser K; Metze D; Weishaupt C; Böhm M
    J Invest Dermatol; 2014 Jan; 134(1):168-175. PubMed ID: 23884247
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potential role of proprotein convertase SKI-1 in the mineralization of primary bone.
    Gorski JP; Huffman NT; Cui C; Henderson EP; Midura RJ; Seidah NG
    Cells Tissues Organs; 2009; 189(1-4):25-32. PubMed ID: 18728345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci.
    Huffman NT; Keightley JA; Chaoying C; Midura RJ; Lovitch D; Veno PA; Dallas SL; Gorski JP
    J Biol Chem; 2007 Sep; 282(36):26002-13. PubMed ID: 17613519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aminoethyl benzenesulfonyl fluoride and its hexapeptide (Ac-VFRSLK) conjugate are both in vitro inhibitors of subtilisin kexin isozyme-1.
    Basak S; Stewart NA; Chrétien M; Basak A
    FEBS Lett; 2004 Aug; 573(1-3):186-94. PubMed ID: 15327996
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.
    Okada T; Haze K; Nadanaka S; Yoshida H; Seidah NG; Hirano Y; Sato R; Negishi M; Mori K
    J Biol Chem; 2003 Aug; 278(33):31024-32. PubMed ID: 12782636
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel antiviral strategy against arenaviruses.
    Rojek JM; Pasqual G; Sanchez AB; Nguyen NT; de la Torre JC; Kunz S
    J Virol; 2010 Jan; 84(1):573-84. PubMed ID: 19846507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of protein-based inhibitors of the proprotein of convertase SKI-1/S1P: processing of SREBP-2, ATF6, and a viral glycoprotein.
    Pullikotil P; Vincent M; Nichol ST; Seidah NG
    J Biol Chem; 2004 Apr; 279(17):17338-47. PubMed ID: 14970232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.
    Atkins GJ; Rowe PS; Lim HP; Welldon KJ; Ormsby R; Wijenayaka AR; Zelenchuk L; Evdokiou A; Findlay DM
    J Bone Miner Res; 2011 Jul; 26(7):1425-36. PubMed ID: 21312267
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents.
    Olmstead AD; Knecht W; Lazarov I; Dixit SB; Jean F
    PLoS Pathog; 2012 Jan; 8(1):e1002468. PubMed ID: 22241994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recombinant expression, purification, and kinetic and inhibitor characterisation of human site-1-protease.
    Bodvard K; Mohlin J; Knecht W
    Protein Expr Purif; 2007 Feb; 51(2):308-19. PubMed ID: 16973377
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel circular, cyclic and acyclic Ψ(CH(2)O) containing peptide inhibitors of SKI-1/S1P: synthesis, kinetic and biochemical evaluations.
    Majumdar S; Chen A; Palmer-Smith H; Basak A
    Curr Med Chem; 2011; 18(18):2770-82. PubMed ID: 21568902
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enediynyl peptides and iso-coumarinyl methyl sulfones as inhibitors of proprotein convertases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, synthesis and biological evaluations.
    Basak A; Goswami M; Rajkumar A; Mitra T; Majumdar S; O'Reilly P; Bdour HM; Trudeau VL; Basak A
    Bioorg Med Chem Lett; 2015; 25(10):2225-37. PubMed ID: 25881830
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular characterization of the processing of arenavirus envelope glycoprotein precursors by subtilisin kexin isozyme-1/site-1 protease.
    Burri DJ; Pasqual G; Rochat C; Seidah NG; Pasquato A; Kunz S
    J Virol; 2012 May; 86(9):4935-46. PubMed ID: 22357276
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The proprotein convertase SKI-1/S1P. In vitro analysis of Lassa virus glycoprotein-derived substrates and ex vivo validation of irreversible peptide inhibitors.
    Pasquato A; Pullikotil P; Asselin MC; Vacatello M; Paolillo L; Ghezzo F; Basso F; Di Bello C; Dettin M; Seidah NG
    J Biol Chem; 2006 Aug; 281(33):23471-81. PubMed ID: 16790437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes.
    Wijayanti N; Kietzmann T; Immenschuh S
    J Biol Chem; 2005 Jun; 280(23):21820-9. PubMed ID: 15833736
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Extracellular matrix mineralization promotes E11/gp38 glycoprotein expression and drives osteocytic differentiation.
    Prideaux M; Loveridge N; Pitsillides AA; Farquharson C
    PLoS One; 2012; 7(5):e36786. PubMed ID: 22586496
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role for serine proteases in mediating phorbol ester-induced differentiation of HL-60 cells.
    Bestilny LJ; Riabowol KT
    Exp Cell Res; 2000 Apr; 256(1):264-71. PubMed ID: 10739673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HtrA1 inhibits mineral deposition by osteoblasts: requirement for the protease and PDZ domains.
    Hadfield KD; Rock CF; Inkson CA; Dallas SL; Sudre L; Wallis GA; Boot-Handford RP; Canfield AE
    J Biol Chem; 2008 Feb; 283(9):5928-38. PubMed ID: 18156628
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells.
    van der Horst G; Farih-Sips H; Löwik CW; Karperien M
    Bone; 2003 Dec; 33(6):899-910. PubMed ID: 14678849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.