BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 21077648)

  • 1. New clues for nephrotoxicity induced by ifosfamide: preferential renal uptake via the human organic cation transporter 2.
    Ciarimboli G; Holle SK; Vollenbröcker B; Hagos Y; Reuter S; Burckhardt G; Bierer S; Herrmann E; Pavenstädt H; Rossi R; Kleta R; Schlatter E
    Mol Pharm; 2011 Feb; 8(1):270-9. PubMed ID: 21077648
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.
    Umehara K; Shirai N; Iwatsubo T; Noguchi K; Usui T; Kamimura H
    Drug Metab Dispos; 2009 Aug; 37(8):1646-57. PubMed ID: 19439489
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
    Schlatter E; Mönnich V; Cetinkaya I; Mehrens T; Ciarimboli G; Hirsch JR; Popp C; Koepsell H
    J Membr Biol; 2002 Oct; 189(3):237-44. PubMed ID: 12395288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2.
    Kimura N; Masuda S; Katsura T; Inui K
    Biochem Pharmacol; 2009 Apr; 77(8):1429-36. PubMed ID: 19426682
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2.
    Ciarimboli G; Ludwig T; Lang D; Pavenstädt H; Koepsell H; Piechota HJ; Haier J; Jaehde U; Zisowsky J; Schlatter E
    Am J Pathol; 2005 Dec; 167(6):1477-84. PubMed ID: 16314463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule.
    Lee WK; Reichold M; Edemir B; Ciarimboli G; Warth R; Koepsell H; Thévenod F
    Am J Physiol Renal Physiol; 2009 Jun; 296(6):F1504-13. PubMed ID: 19357179
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Renal organic cation transporters mediated cadmium-induced nephrotoxicity.
    Soodvilai S; Nantavishit J; Muanprasat C; Chatsudthipong V
    Toxicol Lett; 2011 Jul; 204(1):38-42. PubMed ID: 21513783
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+.
    Thévenod F; Ciarimboli G; Leistner M; Wolff NA; Lee WK; Schatz I; Keller T; Al-Monajjed R; Gorboulev V; Koepsell H
    Mol Pharm; 2013 Aug; 10(8):3045-56. PubMed ID: 23763587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.
    Nakanishi T; Haruta T; Shirasaka Y; Tamai I
    Drug Metab Dispos; 2011 Jan; 39(1):117-22. PubMed ID: 20962061
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).
    Motohashi H; Uwai Y; Hiramoto K; Okuda M; Inui K
    Eur J Pharmacol; 2004 Oct; 503(1-3):25-30. PubMed ID: 15496291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neurotoxic pyridinium metabolites of haloperidol are substrates of human organic cation transporters.
    Kang HJ; Lee SS; Lee CH; Shim JC; Shin HJ; Liu KH; Yoo MA; Shin JG
    Drug Metab Dispos; 2006 Jul; 34(7):1145-51. PubMed ID: 16624869
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kidney transplantation down-regulates expression of organic cation transporters, which translocate β-blockers and fluoroquinolones.
    Ciarimboli G; Schröter R; Neugebauer U; Vollenbröker B; Gabriëls G; Brzica H; Sabolić I; Pietig G; Pavenstädt H; Schlatter E; Edemir B
    Mol Pharm; 2013 Jun; 10(6):2370-80. PubMed ID: 23607617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
    Ito S; Kusuhara H; Yokochi M; Toyoshima J; Inoue K; Yuasa H; Sugiyama Y
    J Pharmacol Exp Ther; 2012 Feb; 340(2):393-403. PubMed ID: 22072731
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney.
    Urakami Y; Kimura N; Okuda M; Inui K
    Pharm Res; 2004 Jun; 21(6):976-81. PubMed ID: 15212162
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.
    Tahara H; Kusuhara H; Endou H; Koepsell H; Imaoka T; Fuse E; Sugiyama Y
    J Pharmacol Exp Ther; 2005 Oct; 315(1):337-45. PubMed ID: 16006492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells.
    Tsuda M; Terada T; Ueba M; Sato T; Masuda S; Katsura T; Inui K
    J Pharmacol Exp Ther; 2009 Apr; 329(1):185-91. PubMed ID: 19164462
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3).
    Bourdet DL; Pritchard JB; Thakker DR
    J Pharmacol Exp Ther; 2005 Dec; 315(3):1288-97. PubMed ID: 16141367
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2.
    Jouan E; Le Vee M; Denizot C; Da Violante G; Fardel O
    Fundam Clin Pharmacol; 2014 Feb; 28(1):65-77. PubMed ID: 22913740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family).
    Yonezawa A; Masuda S; Yokoo S; Katsura T; Inui K
    J Pharmacol Exp Ther; 2006 Nov; 319(2):879-86. PubMed ID: 16914559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional analysis of organic cation transporter OCTNs in mouse renal brush border membrane.
    Kubo Y; Nakamura T; Iwata D; Kato Y; Tsuji A
    Pharmazie; 2006 Feb; 61(2):171. PubMed ID: 16526568
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 11.