236 related articles for article (PubMed ID: 21078189)
1. Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21.
El-Khatib M; Geara F; Haddadin MJ; Gali-Muhtasib H
Radiat Oncol; 2010 Nov; 5():107. PubMed ID: 21078189
[TBL] [Abstract][Full Text] [Related]
2. The quinoxaline di-N-oxide DCQ blocks breast cancer metastasis in vitro and in vivo by targeting the hypoxia inducible factor-1 pathway.
Ghattass K; El-Sitt S; Zibara K; Rayes S; Haddadin MJ; El-Sabban M; Gali-Muhtasib H
Mol Cancer; 2014 Jan; 13():12. PubMed ID: 24461075
[TBL] [Abstract][Full Text] [Related]
3. Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells.
Itani W; Geara F; Haykal J; Haddadin M; Gali-Muhtasib H
Radiat Oncol; 2007 Jan; 2():1. PubMed ID: 17201910
[TBL] [Abstract][Full Text] [Related]
4. Modulation of TRAIL-induced tumor cell apoptosis in a hypoxic environment.
Mayes PA; Campbell L; Ricci MS; Plastaras JP; Dicker DT; El-Deiry WS
Cancer Biol Ther; 2005 Oct; 4(10):1068-74. PubMed ID: 16294025
[TBL] [Abstract][Full Text] [Related]
5. Reduction of HIF-1α/PD-L1 by Catalytic Topoisomerase Inhibitor Induces Cell Death Through Caspase Activation in Cancer Cells Under Hypoxia.
Miyata S; Ishii T; Kitanaka S
Anticancer Res; 2024 Jan; 44(1):49-59. PubMed ID: 38159998
[TBL] [Abstract][Full Text] [Related]
6. Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin.
Ravizza R; Gariboldi MB; Passarelli L; Monti E
BMC Cancer; 2004 Dec; 4():92. PubMed ID: 15601469
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis.
Nardinocchi L; Puca R; Sacchi A; D'Orazi G
Mol Cancer; 2009 Jan; 8():1. PubMed ID: 19128456
[TBL] [Abstract][Full Text] [Related]
8. Rutaecarpine Suppresses Proliferation and Promotes Apoptosis of Human Pulmonary Artery Smooth Muscle Cells in Hypoxia Possibly Through HIF-1α-Dependent Pathways.
Deng J; Qin J; Cai Y; Zhong X; Zhang X; Yu S
J Cardiovasc Pharmacol; 2018 May; 71(5):293-302. PubMed ID: 29438215
[TBL] [Abstract][Full Text] [Related]
9. Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
Zopf S; Neureiter D; Bouralexis S; Abt T; Glaser KB; Okamoto K; Ganslmayer M; Hahn EG; Herold C; Ocker M
Int J Oncol; 2007 Dec; 31(6):1391-402. PubMed ID: 17982666
[TBL] [Abstract][Full Text] [Related]
10. Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5.
Lee SJ; No YR; Dang DT; Dang LH; Yang VW; Shim H; Yun CC
J Biol Chem; 2013 Aug; 288(35):25244-25253. PubMed ID: 23880760
[TBL] [Abstract][Full Text] [Related]
11. HIF-α Promotes Chronic Myelogenous Leukemia Cell Proliferation by Upregulating p21 Expression.
Chen H; Shen Y; Gong F; Jiang Y; Zhang R
Cell Biochem Biophys; 2015 May; 72(1):179-83. PubMed ID: 25596666
[TBL] [Abstract][Full Text] [Related]
12. Role of p21 as a determinant of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane response in human HCT-116 colon carcinoma cells.
Wang JJ; Hung HF; Huang ML; Lee HJ; Chern YT; Chang YF; Chi CW; Hsu YC
Oncol Rep; 2012 Feb; 27(2):529-34. PubMed ID: 22076474
[TBL] [Abstract][Full Text] [Related]
13. CopA3 treatment suppressed multidrug resistivity in HCT-116 cell line by p53-induced degradation of hypoxia-inducible factor 1α.
Dey DK; Gahlot H; Chang SN; Kang SC
Life Sci; 2023 Sep; 329():121933. PubMed ID: 37451396
[TBL] [Abstract][Full Text] [Related]
14. Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells.
Lee E; Choi MK; Han IO; Lim SJ
Exp Mol Med; 2006 Jun; 38(3):325-31. PubMed ID: 16819292
[TBL] [Abstract][Full Text] [Related]
15. A novel oxiranylchromenone derivative, MHY336, induces apoptosis and cell cycle arrest via a p53- and p21-dependent pathway in HCT116 human colon cancer cells.
Lee SH; Kang YJ; Kim DH; Sung B; Kang JA; Chun P; Yoon JH; Moon HR; Kim HS; Chung HY; Kim ND
Int J Oncol; 2014 Mar; 44(3):943-9. PubMed ID: 24365999
[TBL] [Abstract][Full Text] [Related]
16. A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53.
Ghosh A; Sengupta A; Seerapu GPK; Nakhi A; Shivaji Ramarao EVV; Bung N; Bulusu G; Pal M; Haldar D
Biochem Biophys Res Commun; 2017 Jul; 488(3):562-569. PubMed ID: 28526414
[TBL] [Abstract][Full Text] [Related]
17. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
Hayward RL; Schornagel QC; Tente R; Macpherson JS; Aird RE; Guichard S; Habtemariam A; Sadler P; Jodrell DI
Cancer Chemother Pharmacol; 2005 Jun; 55(6):577-83. PubMed ID: 15726367
[TBL] [Abstract][Full Text] [Related]
18. p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.
Furuta T; Hayward RL; Meng LH; Takemura H; Aune GJ; Bonner WM; Aladjem MI; Kohn KW; Pommier Y
Oncogene; 2006 May; 25(20):2839-49. PubMed ID: 16407843
[TBL] [Abstract][Full Text] [Related]
19. Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha.
Nardinocchi L; Puca R; Sacchi A; Rechavi G; Givol D; D'Orazi G
PLoS One; 2009 Aug; 4(8):e6819. PubMed ID: 19714248
[TBL] [Abstract][Full Text] [Related]
20. HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
Ferrandiz N; Martin-Perez J; Blanco R; Donertas D; Weber A; Eilers M; Dotto P; Delgado MD; Leon J
DNA Repair (Amst); 2009 Mar; 8(3):390-9. PubMed ID: 19150257
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
