BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 21080692)

  • 1. Ligand-steered modeling and docking: A benchmarking study in class A G-protein-coupled receptors.
    Phatak SS; Gatica EA; Cavasotto CN
    J Chem Inf Model; 2010 Dec; 50(12):2119-28. PubMed ID: 21080692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homology modeling of G-protein-coupled receptors with X-ray structures on the rise.
    Yarnitzky T; Levit A; Niv MY
    Curr Opin Drug Discov Devel; 2010 May; 13(3):317-25. PubMed ID: 20443165
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.
    Cavasotto CN; Orry AJ; Murgolo NJ; Czarniecki MF; Kocsi SA; Hawes BE; O'Neill KA; Hine H; Burton MS; Voigt JH; Abagyan RA; Bayne ML; Monsma FJ
    J Med Chem; 2008 Feb; 51(3):581-8. PubMed ID: 18198821
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PREDICT modeling and in-silico screening for G-protein coupled receptors.
    Shacham S; Marantz Y; Bar-Haim S; Kalid O; Warshaviak D; Avisar N; Inbal B; Heifetz A; Fichman M; Topf M; Naor Z; Noiman S; Becker OM
    Proteins; 2004 Oct; 57(1):51-86. PubMed ID: 15326594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modeling small molecule-compound binding to G-protein-coupled receptors.
    Vaidehi N; Pease JE; Horuk R
    Methods Enzymol; 2009; 460():263-88. PubMed ID: 19446730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rough set-based proteochemometrics modeling of G-protein-coupled receptor-ligand interactions.
    Strömbergsson H; Prusis P; Midelfart H; Lapinsh M; Wikberg JE; Komorowski J
    Proteins; 2006 Apr; 63(1):24-34. PubMed ID: 16435365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening.
    Klabunde T; Giegerich C; Evers A
    J Med Chem; 2009 May; 52(9):2923-32. PubMed ID: 19374402
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Current assessment of docking into GPCR crystal structures and homology models: successes, challenges, and guidelines.
    Beuming T; Sherman W
    J Chem Inf Model; 2012 Dec; 52(12):3263-77. PubMed ID: 23121495
    [TBL] [Abstract][Full Text] [Related]  

  • 9. From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands.
    Kooistra AJ; Roumen L; Leurs R; de Esch IJ; de Graaf C
    Methods Enzymol; 2013; 522():279-336. PubMed ID: 23374191
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein flexibility in ligand docking and virtual screening to protein kinases.
    Cavasotto CN; Abagyan RA
    J Mol Biol; 2004 Mar; 337(1):209-25. PubMed ID: 15001363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An evaluation of automated in silico ligand docking of amino acid ligands to Family C G-protein coupled receptors.
    Wang M; Hampson DR
    Bioorg Med Chem; 2006 Mar; 14(6):2032-9. PubMed ID: 16297630
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recognition of privileged structures by G-protein coupled receptors.
    Bondensgaard K; Ankersen M; Thøgersen H; Hansen BS; Wulff BS; Bywater RP
    J Med Chem; 2004 Feb; 47(4):888-99. PubMed ID: 14761190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based identification of binding sites, native ligands and potential inhibitors for G-protein coupled receptors.
    Cavasotto CN; Orry AJ; Abagyan RA
    Proteins; 2003 May; 51(3):423-33. PubMed ID: 12696053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Homology modeling and docking evaluation of aminergic G protein-coupled receptors.
    McRobb FM; Capuano B; Crosby IT; Chalmers DK; Yuriev E
    J Chem Inf Model; 2010 Apr; 50(4):626-37. PubMed ID: 20187660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein-based virtual screening of chemical databases. II. Are homology models of G-Protein Coupled Receptors suitable targets?
    Bissantz C; Bernard P; Hibert M; Rognan D
    Proteins; 2003 Jan; 50(1):5-25. PubMed ID: 12471595
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.
    Evers A; Hessler G; Matter H; Klabunde T
    J Med Chem; 2005 Aug; 48(17):5448-65. PubMed ID: 16107144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular modeling of A1 and A2A adenosine receptors: comparison of rhodopsin- and beta2-adrenergic-based homology models through the docking studies.
    Yuzlenko O; Kieć-Kononowicz K
    J Comput Chem; 2009 Jan; 30(1):14-32. PubMed ID: 18496794
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Revisiting automated G-protein coupled receptor modeling: the benefit of additional template structures for a neurokinin-1 receptor model.
    Kneissl B; Leonhardt B; Hildebrandt A; Tautermann CS
    J Med Chem; 2009 May; 52(10):3166-73. PubMed ID: 19397376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modern homology modeling of G-protein coupled receptors: which structural template to use?
    Mobarec JC; Sanchez R; Filizola M
    J Med Chem; 2009 Aug; 52(16):5207-16. PubMed ID: 19627087
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).
    Floquet N; M'Kadmi C; Perahia D; Gagne D; Bergé G; Marie J; Banères JL; Galleyrand JC; Fehrentz JA; Martinez J
    J Mol Biol; 2010 Jan; 395(4):769-84. PubMed ID: 19782690
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.