351 related articles for article (PubMed ID: 21080725)
21. Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4.
Hall JJ; Sriram M; Strecker TE; Tidmore JK; Jelinek CJ; Kumar GD; Hadimani MB; Pettit GR; Chaplin DJ; Trawick ML; Pinney KG
Bioorg Med Chem Lett; 2008 Sep; 18(18):5146-9. PubMed ID: 18710804
[TBL] [Abstract][Full Text] [Related]
22. Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity.
Simoni D; Romagnoli R; Baruchello R; Rondanin R; Grisolia G; Eleopra M; Rizzi M; Tolomeo M; Giannini G; Alloatti D; Castorina M; Marcellini M; Pisano C
J Med Chem; 2008 Oct; 51(19):6211-5. PubMed ID: 18783207
[TBL] [Abstract][Full Text] [Related]
23. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
Ruan BF; Lu X; Li TT; Tang JF; Wei Y; Wang XL; Zheng SL; Yao RS; Zhu HL
Bioorg Med Chem; 2012 Jan; 20(2):1113-21. PubMed ID: 22189271
[TBL] [Abstract][Full Text] [Related]
24. Synthesis, biological evaluation, and structure-activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors.
Aziz J; Brachet E; Hamze A; Peyrat JF; Bernadat G; Morvan E; Bignon J; Wdzieczak-Bakala J; Desravines D; Dubois J; Tueni M; Yassine A; Brion JD; Alami M
Org Biomol Chem; 2013 Jan; 11(3):430-42. PubMed ID: 23047722
[TBL] [Abstract][Full Text] [Related]
25. Synthesis and biological evaluation of 1,4-diaryl-2-azetidinones as specific anticancer agents: activation of adenosine monophosphate activated protein kinase and induction of apoptosis.
Tripodi F; Pagliarin R; Fumagalli G; Bigi A; Fusi P; Orsini F; Frattini M; Coccetti P
J Med Chem; 2012 Mar; 55(5):2112-24. PubMed ID: 22329561
[TBL] [Abstract][Full Text] [Related]
26. New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
De Martino G; Edler MC; La Regina G; Coluccia A; Barbera MC; Barrow D; Nicholson RI; Chiosis G; Brancale A; Hamel E; Artico M; Silvestri R
J Med Chem; 2006 Feb; 49(3):947-54. PubMed ID: 16451061
[TBL] [Abstract][Full Text] [Related]
27. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
Greene TF; Wang S; Greene LM; Nathwani SM; Pollock JK; Malebari AM; McCabe T; Twamley B; O'Boyle NM; Zisterer DM; Meegan MJ
J Med Chem; 2016 Jan; 59(1):90-113. PubMed ID: 26680364
[TBL] [Abstract][Full Text] [Related]
28. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.
Malebari AM; Fayne D; Nathwani SM; O'Connell F; Noorani S; Twamley B; O'Boyle NM; O'Sullivan J; Zisterer DM; Meegan MJ
Eur J Med Chem; 2020 Mar; 189():112050. PubMed ID: 31954879
[TBL] [Abstract][Full Text] [Related]
29. New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation.
Borrel C; Thoret S; Cachet X; Guénard D; Tillequin F; Koch M; Michel S
Bioorg Med Chem; 2005 Jun; 13(11):3853-64. PubMed ID: 15863010
[TBL] [Abstract][Full Text] [Related]
30. Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents.
Hu Y; Lu X; Chen K; Yan R; Li QS; Zhu HL
Bioorg Med Chem; 2012 Jan; 20(2):903-9. PubMed ID: 22192936
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.
Zheng CH; Chen J; Liu J; Zhou XT; Liu N; Shi D; Huang JJ; Lv JG; Zhu J; Zhou YJ
Arch Pharm (Weinheim); 2012 Jun; 345(6):454-62. PubMed ID: 22415658
[TBL] [Abstract][Full Text] [Related]
32. Naphthalene combretastatin analogues: synthesis, cytotoxicity and antitubulin activity.
Medarde M; Maya AB; Pérez-Melero C
J Enzyme Inhib Med Chem; 2004 Dec; 19(6):521-40. PubMed ID: 15662956
[TBL] [Abstract][Full Text] [Related]
33. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
Nakamura M; Kajita D; Matsumoto Y; Hashimoto Y
Bioorg Med Chem; 2013 Dec; 21(23):7381-91. PubMed ID: 24139940
[TBL] [Abstract][Full Text] [Related]
34. Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
La Regina G; Edler MC; Brancale A; Kandil S; Coluccia A; Piscitelli F; Hamel E; De Martino G; Matesanz R; Díaz JF; Scovassi AI; Prosperi E; Lavecchia A; Novellino E; Artico M; Silvestri R
J Med Chem; 2007 Jun; 50(12):2865-74. PubMed ID: 17497841
[TBL] [Abstract][Full Text] [Related]
35. Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor.
Ganina OG; Daras E; Bourgarel-Rey V; Peyrot V; Andresyuk AN; Finet JP; Fedorov AY; Beletskaya IP; Combes S
Bioorg Med Chem; 2008 Oct; 16(19):8806-12. PubMed ID: 18805012
[TBL] [Abstract][Full Text] [Related]
36. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
Barnes NG; Parker AW; Ahmed Mal Ullah AA; Ragazzon PA; Hadfield JA
Bioorg Med Chem; 2020 Oct; 28(19):115684. PubMed ID: 32912434
[TBL] [Abstract][Full Text] [Related]
37. The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
Greene LM; Nathwani SM; Bright SA; Fayne D; Croke A; Gagliardi M; McElligott AM; O'Connor L; Carr M; Keely NO; O'Boyle NM; Carroll P; Sarkadi B; Conneally E; Lloyd DG; Lawler M; Meegan MJ; Zisterer DM
J Pharmacol Exp Ther; 2010 Nov; 335(2):302-13. PubMed ID: 20699436
[TBL] [Abstract][Full Text] [Related]
38. The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4.
Kerr DJ; Hamel E; Jung MK; Flynn BL
Bioorg Med Chem; 2007 May; 15(9):3290-8. PubMed ID: 17360188
[TBL] [Abstract][Full Text] [Related]
39. 4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles that are cytotoxic against combretastatin A resistant tumor cells and vascular disrupting in a cisplatin resistant germ cell tumor model.
Schobert R; Biersack B; Dietrich A; Effenberger K; Knauer S; Mueller T
J Med Chem; 2010 Sep; 53(18):6595-602. PubMed ID: 20731355
[TBL] [Abstract][Full Text] [Related]
40. Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents.
Reddy MA; Jain N; Yada D; Kishore C; Vangala JR; P Surendra R; Addlagatta A; Kalivendi SV; Sreedhar B
J Med Chem; 2011 Oct; 54(19):6751-60. PubMed ID: 21851083
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
