BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

342 related articles for article (PubMed ID: 21081503)

  • 1. RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.
    Guderian G; Peter C; Wiesner J; Sickmann A; Schulze-Osthoff K; Fischer U; Grimmler M
    J Biol Chem; 2011 Jan; 286(3):1976-86. PubMed ID: 21081503
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex.
    Krzyzanowski A; Gasper R; Adihou H; Hart P'; Waldmann H
    Chembiochem; 2021 Jun; 22(11):1908-1914. PubMed ID: 33624332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis for substrate recruitment to the PRMT5 methylosome.
    Mulvaney KM; Blomquist C; Acharya N; Li R; Ranaghan MJ; O'Keefe M; Rodriguez DJ; Young MJ; Kesar D; Pal D; Stokes M; Nelson AJ; Jain SS; Yang A; Mullin-Bernstein Z; Columbus J; Bozal FK; Skepner A; Raymond D; LaRussa S; McKinney DC; Freyzon Y; Baidi Y; Porter D; Aguirre AJ; Ianari A; McMillan B; Sellers WR
    Mol Cell; 2021 Sep; 81(17):3481-3495.e7. PubMed ID: 34358446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NF90/NFAR (nuclear factors associated with dsRNA) - a new methylation substrate of the PRMT5-WD45-RioK1 complex.
    Cox J; Esser LM; Jüdt M; Schmitz K; Reiffert K; Grimmler M; Stork B; Wesselborg S; Peter C
    Biol Chem; 2022 Sep; 403(10):907-915. PubMed ID: 36040368
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel WD repeat protein component of the methylosome binds Sm proteins.
    Friesen WJ; Wyce A; Paushkin S; Abel L; Rappsilber J; Mann M; Dreyfuss G
    J Biol Chem; 2002 Mar; 277(10):8243-7. PubMed ID: 11756452
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer.
    Beketova E; Fang S; Owens JL; Liu S; Chen X; Zhang Q; Asberry AM; Deng X; Malola J; Huang J; Li C; Pili R; Elzey BD; Ratliff TL; Wan J; Hu CD
    Cancer Res; 2020 Nov; 80(22):4904-4917. PubMed ID: 32999000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
    Stopa N; Krebs JE; Shechter D
    Cell Mol Life Sci; 2015 Jun; 72(11):2041-59. PubMed ID: 25662273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of pICLn in methylation of Sm proteins by PRMT5.
    Pesiridis GS; Diamond E; Van Duyne GD
    J Biol Chem; 2009 Aug; 284(32):21347-59. PubMed ID: 19520849
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The exon junction complex component Y14 modulates the activity of the methylosome in biogenesis of spliceosomal small nuclear ribonucleoproteins.
    Chuang TW; Peng PJ; Tarn WY
    J Biol Chem; 2011 Mar; 286(11):8722-8. PubMed ID: 21209085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln.
    Meister G; Eggert C; Bühler D; Brahms H; Kambach C; Fischer U
    Curr Biol; 2001 Dec; 11(24):1990-4. PubMed ID: 11747828
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.
    Burgos ES; Wilczek C; Onikubo T; Bonanno JB; Jansong J; Reimer U; Shechter D
    J Biol Chem; 2015 Apr; 290(15):9674-89. PubMed ID: 25713080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.
    Azzouz TN; Pillai RS; Däpp C; Chari A; Meister G; Kambach C; Fischer U; Schümperli D
    J Biol Chem; 2005 Oct; 280(41):34435-40. PubMed ID: 16087681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.
    Chari A; Golas MM; Klingenhäger M; Neuenkirchen N; Sander B; Englbrecht C; Sickmann A; Stark H; Fischer U
    Cell; 2008 Oct; 135(3):497-509. PubMed ID: 18984161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.
    Wang M; Fuhrmann J; Thompson PR
    Biochemistry; 2014 Dec; 53(50):7884-92. PubMed ID: 25485739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation.
    Prusty AB; Meduri R; Prusty BK; Vanselow J; Schlosser A; Fischer U
    J Cell Biol; 2017 Aug; 216(8):2391-2407. PubMed ID: 28637748
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome.
    Yang XC; Desotell A; Lin MH; Paige AS; Malinowska A; Sun Y; Aik WS; Dadlez M; Tong L; Dominski Z
    RNA; 2023 Nov; 29(11):1673-1690. PubMed ID: 37562960
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors.
    Krzyzanowski A; Esser LM; Willaume A; Prudent R; Peter C; 't Hart P; Waldmann H
    J Med Chem; 2022 Nov; 65(22):15300-15311. PubMed ID: 36378254
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LKB1 regulates PRMT5 activity in breast cancer.
    Lattouf H; Kassem L; Jacquemetton J; Choucair A; Poulard C; Trédan O; Corbo L; Diab-Assaf M; Hussein N; Treilleux I; Le Romancer M
    Int J Cancer; 2019 Feb; 144(3):595-606. PubMed ID: 30289978
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene.
    Barbarossa A; Antoine E; Neel H; Gostan T; Soret J; Bordonné R
    Mol Cell Biol; 2014 Feb; 34(4):595-605. PubMed ID: 24298023
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
    McKinney DC; McMillan BJ; Ranaghan MJ; Moroco JA; Brousseau M; Mullin-Bernstein Z; O'Keefe M; McCarren P; Mesleh MF; Mulvaney KM; Robinson F; Singh R; Bajrami B; Wagner FF; Hilgraf R; Drysdale MJ; Campbell AJ; Skepner A; Timm DE; Porter D; Kaushik VK; Sellers WR; Ianari A
    J Med Chem; 2021 Aug; 64(15):11148-11168. PubMed ID: 34342224
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.