These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 21083052)

  • 1. Microdosing: a valuable tool for accelerating drug development and the role of bioanalytical methods in meeting the challenge.
    Ings RM
    Bioanalysis; 2009 Oct; 1(7):1293-305. PubMed ID: 21083052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometry.
    Balani SK; Nagaraja NV; Qian MG; Costa AO; Daniels JS; Yang H; Shimoga PR; Wu JT; Gan LS; Lee FW; Miwa GT
    Drug Metab Dispos; 2006 Mar; 34(3):384-8. PubMed ID: 16326814
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of microdosing strategies for studies in preclinical drug development: demonstration of linear pharmacokinetics in dogs of a nucleoside analog over a 50-fold dose range.
    Sandhu P; Vogel JS; Rose MJ; Ubick EA; Brunner JE; Wallace MA; Adelsberger JK; Baker MP; Henderson PT; Pearson PG; Baillie TA
    Drug Metab Dispos; 2004 Nov; 32(11):1254-9. PubMed ID: 15286054
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New ultrasensitive detection technologies and techniques for use in microdosing studies.
    Lappin G; Wagner CC; Langer O; van de Merbel N
    Bioanalysis; 2009 May; 1(2):357-66. PubMed ID: 21083172
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Practical experience of using human microdosing with AMS analysis to obtain early human drug metabolism and PK data.
    Garner RC
    Bioanalysis; 2010 Mar; 2(3):429-40. PubMed ID: 21083253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microdosing studies using accelerated mass spectrometry as exploratory investigational new drug trials.
    Bae SK; Shon JH
    Arch Pharm Res; 2011 Nov; 34(11):1789-98. PubMed ID: 22139681
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Accelerator MS: its role as a frontline bioanalytical technique.
    Seymour MA
    Bioanalysis; 2011 Dec; 3(24):2817-23. PubMed ID: 22185281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recent development in high-throughput bioanalytical support for in vitro ADMET profiling.
    Shou WZ; Zhang J
    Expert Opin Drug Metab Toxicol; 2010 Mar; 6(3):321-36. PubMed ID: 20163321
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mass spectrometric techniques for label-free high-throughput screening in drug discovery.
    Roddy TP; Horvath CR; Stout SJ; Kenney KL; Ho PI; Zhang JH; Vickers C; Kaushik V; Hubbard B; Wang YK
    Anal Chem; 2007 Nov; 79(21):8207-13. PubMed ID: 17902631
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel strategies for microdose studies using non-radiolabeled compounds.
    Maeda K; Sugiyama Y
    Adv Drug Deliv Rev; 2011 Jun; 63(7):532-8. PubMed ID: 21345359
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analytical strategies for identifying drug metabolites.
    Prakash C; Shaffer CL; Nedderman A
    Mass Spectrom Rev; 2007; 26(3):340-69. PubMed ID: 17405144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Big physics, small doses: the use of AMS and PET in human microdosing of development drugs.
    Lappin G; Garner RC
    Nat Rev Drug Discov; 2003 Mar; 2(3):233-40. PubMed ID: 12612650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances in high-throughput quantitative bioanalysis by LC-MS/MS.
    Xu RN; Fan L; Rieser MJ; El-Shourbagy TA
    J Pharm Biomed Anal; 2007 Jun; 44(2):342-55. PubMed ID: 17360141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.
    Yamazaki A; Kumagai Y; Yamane N; Tozuka Z; Sugiyama Y; Fujita T; Yokota S; Maeda M
    J Clin Pharm Ther; 2010 Apr; 35(2):169-75. PubMed ID: 20456735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.
    Chovan LE; Black-Schaefer C; Dandliker PJ; Lau YY
    Rapid Commun Mass Spectrom; 2004; 18(24):3105-12. PubMed ID: 15565734
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Accelerator mass spectrometry offers new opportunities for microdosing of peptide and protein pharmaceuticals.
    Salehpour M; Ekblom J; Sabetsky V; Håkansson K; Possnert G
    Rapid Commun Mass Spectrom; 2010 May; 24(10):1481-9. PubMed ID: 20411588
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microfluidic chip-based liquid chromatography coupled to mass spectrometry for determination of small molecules in bioanalytical applications.
    Lin SL; Bai HY; Lin TY; Fuh MR
    Electrophoresis; 2012 Feb; 33(4):635-43. PubMed ID: 22451056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations.
    Srinivas NR
    Biomed Chromatogr; 2006 May; 20(5):383-414. PubMed ID: 16307470
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AMS method validation for quantitation in pharmacokinetic studies with concomitant extravascular and intravenous administration.
    Lappin G; Seymour M; Young G; Higton D; Hill HM
    Bioanalysis; 2011 Feb; 3(4):393-405. PubMed ID: 21338259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 'LC-electrolyte effects' improve the bioanalytical performance of liquid chromatography/tandem mass spectrometric assays in supporting pharmacokinetic study for drug discovery.
    Wang L; Sun Y; Du F; Niu W; Lu T; Kan J; Xu F; Yuan K; Qin T; Liu C; Li C
    Rapid Commun Mass Spectrom; 2007; 21(16):2573-84. PubMed ID: 17639570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.