BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 21084384)

  • 21. L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport.
    Peyrollier K; Hajduch E; Blair AS; Hyde R; Hundal HS
    Biochem J; 2000 Sep; 350 Pt 2(Pt 2):361-8. PubMed ID: 10947949
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver.
    Reiter AK; Anthony TG; Anthony JC; Jefferson LS; Kimball SR
    Int J Biochem Cell Biol; 2004 Nov; 36(11):2169-79. PubMed ID: 15313464
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX; Yang X; Sreejayan N; Ren J
    Exp Neurol; 2007 Jan; 203(1):196-204. PubMed ID: 16962100
    [TBL] [Abstract][Full Text] [Related]  

  • 24. mTOR, AMPK, and GCN2 coordinate the adaptation of hepatic energy metabolic pathways in response to protein intake in the rat.
    Chotechuang N; Azzout-Marniche D; Bos C; Chaumontet C; Gausserès N; Steiler T; Gaudichon C; Tomé D
    Am J Physiol Endocrinol Metab; 2009 Dec; 297(6):E1313-23. PubMed ID: 19738034
    [TBL] [Abstract][Full Text] [Related]  

  • 25. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    Li CM; Narayanan R; Lu Y; Hurh E; Coss CC; Barrett CM; Miller DD; Dalton JT
    Int J Oncol; 2010 Oct; 37(4):1023-30. PubMed ID: 20811725
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli.
    Eley HL; Russell ST; Baxter JH; Mukerji P; Tisdale MJ
    Am J Physiol Endocrinol Metab; 2007 Oct; 293(4):E923-31. PubMed ID: 17609254
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFbeta1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells.
    Chen YJ; Hsiao PW; Lee MT; Mason JI; Ke FC; Hwang JJ
    J Endocrinol; 2007 Feb; 192(2):405-19. PubMed ID: 17283241
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway.
    Li B; Takeda T; Tsuiji K; Kondo A; Kitamura M; Wong TF; Yaegashi N
    Gynecol Endocrinol; 2013 Jan; 29(1):87-90. PubMed ID: 22835064
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Down-regulation of the ubiquitin-proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes.
    Chotechuang N; Azzout-Marniche D; Bos C; Chaumontet C; Gaudichon C; Tomé D
    Amino Acids; 2011 Jul; 41(2):457-68. PubMed ID: 20957397
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
    Lin CC; Yeh HH; Huang WL; Yan JJ; Lai WW; Su WP; Chen HH; Su WC
    Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
    [TBL] [Abstract][Full Text] [Related]  

  • 31. AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons.
    Ishizuka Y; Kakiya N; Witters LA; Oshiro N; Shirao T; Nawa H; Takei N
    J Neurochem; 2013 Oct; 127(1):66-77. PubMed ID: 23841933
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells.
    Zakikhani M; Blouin MJ; Piura E; Pollak MN
    Breast Cancer Res Treat; 2010 Aug; 123(1):271-9. PubMed ID: 20135346
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Troglitazone acutely activates AMP-activated protein kinase and inhibits insulin secretion from beta cells.
    Wang X; Zhou L; Shao L; Qian L; Fu X; Li G; Luo T; Gu Y; Li F; Li J; Zheng S; Luo M
    Life Sci; 2007 Jun; 81(2):160-5. PubMed ID: 17544010
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Intracerebroventricular administration of metformin inhibits ghrelin-induced Hypothalamic AMP-kinase signalling and food intake.
    Stevanovic D; Janjetovic K; Misirkic M; Vucicevic L; Sumarac-Dumanovic M; Micic D; Starcevic V; Trajkovic V
    Neuroendocrinology; 2012; 96(1):24-31. PubMed ID: 22343549
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Metformin preconditioning protects Daphnia pulex from lethal hypoxic insult involving AMPK, HIF and mTOR signaling.
    Sheng B; Liu J; Li GH
    Comp Biochem Physiol B Biochem Mol Biol; 2012 Sep; 163(1):51-8. PubMed ID: 22564403
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.
    Hinke SA; Martens GA; Cai Y; Finsi J; Heimberg H; Pipeleers D; Van de Casteele M
    Br J Pharmacol; 2007 Apr; 150(8):1031-43. PubMed ID: 17339833
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
    Farrelly AM; Kilbride SM; Bonner C; Prehn JH; Byrne MM
    Apoptosis; 2011 Nov; 16(11):1128-37. PubMed ID: 21874357
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Metformin promotes irisin release from murine skeletal muscle independently of AMP-activated protein kinase activation.
    Li DJ; Huang F; Lu WJ; Jiang GJ; Deng YP; Shen FM
    Acta Physiol (Oxf); 2015 Mar; 213(3):711-21. PubMed ID: 25382002
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin.
    Kwon B; Querfurth HW
    Biochimie; 2015 Nov; 118():141-50. PubMed ID: 26344902
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase.
    Zakikhani M; Dowling RJ; Sonenberg N; Pollak MN
    Cancer Prev Res (Phila); 2008 Oct; 1(5):369-75. PubMed ID: 19138981
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.