129 related articles for article (PubMed ID: 21090651)
1. Discovery of non-glycoside sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening.
Wu JS; Peng YH; Wu JM; Hsieh CJ; Wu SH; Coumar MS; Song JS; Lee JC; Tsai CH; Chen CT; Liu YW; Chao YS; Wu SY
J Med Chem; 2010 Dec; 53(24):8770-4. PubMed ID: 21090651
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors.
Yao CH; Song JS; Chen CT; Yeh TK; Hsieh TC; Wu SH; Huang CY; Huang YL; Wang MH; Liu YW; Tsai CH; Kumar CR; Lee JC
Eur J Med Chem; 2012 Sep; 55():32-8. PubMed ID: 22818040
[TBL] [Abstract][Full Text] [Related]
3. Identification of novel serotonin 2C receptor ligands by sequential virtual screening.
Ahmed A; Choo H; Cho YS; Park WK; Pae AN
Bioorg Med Chem; 2009 Jul; 17(13):4559-68. PubMed ID: 19464901
[TBL] [Abstract][Full Text] [Related]
4. Development and application of a fluorescent glucose uptake assay for the high-throughput screening of non-glycoside SGLT2 inhibitors.
Wu SH; Yao CH; Hsieh CJ; Liu YW; Chao YS; Song JS; Lee JC
Eur J Pharm Sci; 2015 Jul; 74():40-4. PubMed ID: 25819489
[TBL] [Abstract][Full Text] [Related]
5. A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design.
Sanders MP; Roumen L; van der Horst E; Lane JR; Vischer HF; van Offenbeek J; de Vries H; Verhoeven S; Chow KY; Verkaar F; Beukers MW; McGuire R; Leurs R; Ijzerman AP; de Vlieg J; de Esch IJ; Zaman GJ; Klomp JP; Bender A; de Graaf C
J Med Chem; 2012 Jun; 55(11):5311-25. PubMed ID: 22563707
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and discovery of novel non-peptide inhibitor of Caspase-3 using ligand based and structure based virtual screening approach.
Lakshmi PJ; Kumar BV; Nayana RS; Mohan MS; Bolligarla R; Das SK; Bhanu MU; Kondapi AK; Ravikumar M
Bioorg Med Chem; 2009 Aug; 17(16):6040-7. PubMed ID: 19631549
[TBL] [Abstract][Full Text] [Related]
7. Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.
Yao CH; Song JS; Chen CT; Yeh TK; Hung MS; Chang CC; Liu YW; Yuan MC; Hsieh CJ; Huang CY; Wang MH; Chiu CH; Hsieh TC; Wu SH; Hsiao WC; Chu KF; Tsai CH; Chao YS; Lee JC
J Med Chem; 2011 Jan; 54(1):166-78. PubMed ID: 21128592
[TBL] [Abstract][Full Text] [Related]
8. Strategies for generating less toxic P-selectin inhibitors: pharmacophore modeling, virtual screening and counter pharmacophore screening to remove toxic hits.
Ananthula RS; Ravikumar M; Pramod AB; Madala KK; Mahmood SK
J Mol Graph Model; 2008 Nov; 27(4):546-57. PubMed ID: 18993099
[TBL] [Abstract][Full Text] [Related]
9. C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization.
Robinson RP; Mascitti V; Boustany-Kari CM; Carr CL; Foley PM; Kimoto E; Leininger MT; Lowe A; Klenotic MK; Macdonald JI; Maguire RJ; Masterson VM; Maurer TS; Miao Z; Patel JD; Préville C; Reese MR; She L; Steppan CM; Thuma BA; Zhu T
Bioorg Med Chem Lett; 2010 Mar; 20(5):1569-72. PubMed ID: 20149653
[TBL] [Abstract][Full Text] [Related]
10. A specific pharmacophore model of sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Tang C; Zhu X; Huang D; Zan X; Yang B; Li Y; Du X; Qian H; Huang W
J Mol Model; 2012 Jun; 18(6):2795-804. PubMed ID: 22120948
[TBL] [Abstract][Full Text] [Related]
11. Evolution of sodium glucose co-transporter 2 inhibitors as anti-diabetic agents.
Washburn WN
Expert Opin Ther Pat; 2009 Nov; 19(11):1485-99. PubMed ID: 19852718
[TBL] [Abstract][Full Text] [Related]
12. Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.
Cavasotto CN; Orry AJ; Murgolo NJ; Czarniecki MF; Kocsi SA; Hawes BE; O'Neill KA; Hine H; Burton MS; Voigt JH; Abagyan RA; Bayne ML; Monsma FJ
J Med Chem; 2008 Feb; 51(3):581-8. PubMed ID: 18198821
[TBL] [Abstract][Full Text] [Related]
13. Identification of potent urease inhibitors via ligand- and structure-based virtual screening and in vitro assays.
Khan KM; Wadood A; Ali M; Zia-Ullah ; Ul-Haq Z; Lodhi MA; Khan M; Perveen S; Choudhary MI
J Mol Graph Model; 2010 Jun; 28(8):792-8. PubMed ID: 20338793
[TBL] [Abstract][Full Text] [Related]
14. Pharmacophore modeling and in silico screening for new KDR kinase inhibitors.
Yu H; Wang Z; Zhang L; Zhang J; Huang Q
Bioorg Med Chem Lett; 2007 Apr; 17(8):2126-33. PubMed ID: 17306530
[TBL] [Abstract][Full Text] [Related]
15. Novel 2D fingerprints for ligand-based virtual screening.
Ewing T; Baber JC; Feher M
J Chem Inf Model; 2006; 46(6):2423-31. PubMed ID: 17125184
[TBL] [Abstract][Full Text] [Related]
16. A selectivity study of sodium-dependent glucose cotransporter 2/sodium-dependent glucose cotransporter 1 inhibitors by molecular modeling.
Xu J; Yuan H; Ran T; Zhang Y; Liu H; Lu S; Xiong X; Xu A; Jiang Y; Lu T; Chen Y
J Mol Recognit; 2015 Aug; 28(8):467-79. PubMed ID: 25753971
[TBL] [Abstract][Full Text] [Related]
17. Novel macrocyclic C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents.
Kim MJ; Lee SH; Park SO; Kang H; Lee JS; Lee KN; Jung ME; Kim J; Lee J
Bioorg Med Chem; 2011 Sep; 19(18):5468-79. PubMed ID: 21868239
[TBL] [Abstract][Full Text] [Related]
18. On the value of homology models for virtual screening: discovering hCXCR3 antagonists by pharmacophore-based and structure-based approaches.
Huang D; Gu Q; Ge H; Ye J; Salam NK; Hagler A; Chen H; Xu J
J Chem Inf Model; 2012 May; 52(5):1356-66. PubMed ID: 22545675
[TBL] [Abstract][Full Text] [Related]
19. Discovery of tofogliflozin, a novel C-arylglucoside with an O-spiroketal ring system, as a highly selective sodium glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
Ohtake Y; Sato T; Kobayashi T; Nishimoto M; Taka N; Takano K; Yamamoto K; Ohmori M; Yamaguchi M; Takami K; Yeu SY; Ahn KH; Matsuoka H; Morikawa K; Suzuki M; Hagita H; Ozawa K; Yamaguchi K; Kato M; Ikeda S
J Med Chem; 2012 Sep; 55(17):7828-40. PubMed ID: 22889351
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow.
Markt P; Feldmann C; Rollinger JM; Raduner S; Schuster D; Kirchmair J; Distinto S; Spitzer GM; Wolber G; Laggner C; Altmann KH; Langer T; Gertsch J
J Med Chem; 2009 Jan; 52(2):369-78. PubMed ID: 19143566
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
