261 related articles for article (PubMed ID: 21093322)
1. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.
Gómez-del Arco P; Kashiwagi M; Jackson AF; Naito T; Zhang J; Liu F; Kee B; Vooijs M; Radtke F; Redondo JM; Georgopoulos K
Immunity; 2010 Nov; 33(5):685-98. PubMed ID: 21093322
[TBL] [Abstract][Full Text] [Related]
2. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P
Blood; 2010 Dec; 116(25):5443-54. PubMed ID: 20829372
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2.
Dovat E; Song C; Hu T; Rahman MA; Dhanyamraju PK; Klink M; Bogush D; Soliman M; Kane S; McGrath M; Ding Y; Desai D; Sharma A; Gowda C
Int J Mol Sci; 2021 Jan; 22(2):. PubMed ID: 33467550
[TBL] [Abstract][Full Text] [Related]
4. MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
Pajcini KV; Xu L; Shao L; Petrovic J; Palasiewicz K; Ohtani Y; Bailis W; Lee C; Wertheim GB; Mani R; Muthusamy N; Li Y; Meijerink JPP; Blacklow SC; Faryabi RB; Cherry S; Pear WS
Sci Signal; 2017 Nov; 10(505):. PubMed ID: 29138297
[TBL] [Abstract][Full Text] [Related]
5. Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.
Dail M; Li Q; McDaniel A; Wong J; Akagi K; Huang B; Kang HC; Kogan SC; Shokat K; Wolff L; Braun BS; Shannon K
Proc Natl Acad Sci U S A; 2010 Mar; 107(11):5106-11. PubMed ID: 20194733
[TBL] [Abstract][Full Text] [Related]
6. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL.
Sontani Y; Chapman G; Papathanasiou P; Dunwoodie S; Goodnow CC; Hoyne GF
Leuk Res; 2011 Nov; 35(11):1512-9. PubMed ID: 21840596
[TBL] [Abstract][Full Text] [Related]
7. Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice.
Dumortier A; Jeannet R; Kirstetter P; Kleinmann E; Sellars M; dos Santos NR; Thibault C; Barths J; Ghysdael J; Punt JA; Kastner P; Chan S
Mol Cell Biol; 2006 Jan; 26(1):209-20. PubMed ID: 16354692
[TBL] [Abstract][Full Text] [Related]
8. Monoallelic
Veiga DFT; Tremblay M; Gerby B; Herblot S; Haman A; Gendron P; Lemieux S; Zúñiga-Pflücker JC; Hébert J; Cohen JP; Hoang T
Front Immunol; 2022; 13():867443. PubMed ID: 35401501
[TBL] [Abstract][Full Text] [Related]
9. Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
Witkowski MT; Cimmino L; Hu Y; Trimarchi T; Tagoh H; McKenzie MD; Best SA; Tuohey L; Willson TA; Nutt SL; Busslinger M; Aifantis I; Smyth GK; Dickins RA
Leukemia; 2015 Jun; 29(6):1301-11. PubMed ID: 25655195
[TBL] [Abstract][Full Text] [Related]
10. Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.
Ashworth TD; Pear WS; Chiang MY; Blacklow SC; Mastio J; Xu L; Kelliher M; Kastner P; Chan S; Aster JC
Blood; 2010 Dec; 116(25):5455-64. PubMed ID: 20852131
[TBL] [Abstract][Full Text] [Related]
11. Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulation.
Kathrein KL; Chari S; Winandy S
J Biol Chem; 2008 Apr; 283(16):10476-84. PubMed ID: 18287091
[TBL] [Abstract][Full Text] [Related]
12. Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.
Matsushita K; Kitamura K; Rahmutulla B; Tanaka N; Ishige T; Satoh M; Hoshino T; Miyagi S; Mori T; Itoga S; Shimada H; Tomonaga T; Kito M; Nakajima-Takagi Y; Kubo S; Nakaseko C; Hatano M; Miki T; Matsuo M; Fukuyo M; Kaneda A; Iwama A; Nomura F
Oncotarget; 2015 Mar; 6(7):5102-17. PubMed ID: 25671302
[TBL] [Abstract][Full Text] [Related]
13. Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.
Rakowski LA; Garagiola DD; Li CM; Decker M; Caruso S; Jones M; Kuick R; Cierpicki T; Maillard I; Chiang MY
Cancer Res; 2013 Jan; 73(2):930-41. PubMed ID: 23161489
[TBL] [Abstract][Full Text] [Related]
14. The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.
Choi SH; Severson E; Pear WS; Liu XS; Aster JC; Blacklow SC
PLoS One; 2017; 12(10):e0185762. PubMed ID: 29023469
[TBL] [Abstract][Full Text] [Related]
15. Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia.
Yoshida N; Sakaguchi H; Muramatsu H; Okuno Y; Song C; Dovat S; Shimada A; Ozeki M; Ohnishi H; Teramoto T; Fukao T; Kondo N; Takahashi Y; Matsumoto K; Kato K; Kojima S
Leukemia; 2017 May; 31(5):1221-1223. PubMed ID: 28096536
[No Abstract] [Full Text] [Related]
16. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells.
Gerby B; Tremblay CS; Tremblay M; Rojas-Sutterlin S; Herblot S; Hébert J; Sauvageau G; Lemieux S; Lécuyer E; Veiga DF; Hoang T
PLoS Genet; 2014 Dec; 10(12):e1004768. PubMed ID: 25522233
[TBL] [Abstract][Full Text] [Related]
17. Notch dimerization is required for leukemogenesis and T-cell development.
Liu H; Chi AW; Arnett KL; Chiang MY; Xu L; Shestova O; Wang H; Li YM; Bhandoola A; Aster JC; Blacklow SC; Pear WS
Genes Dev; 2010 Nov; 24(21):2395-407. PubMed ID: 20935071
[TBL] [Abstract][Full Text] [Related]
18. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.
Yatim A; Benne C; Sobhian B; Laurent-Chabalier S; Deas O; Judde JG; Lelievre JD; Levy Y; Benkirane M
Mol Cell; 2012 Nov; 48(3):445-58. PubMed ID: 23022380
[TBL] [Abstract][Full Text] [Related]
19. Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.
Berquam-Vrieze KE; Swing DA; Tessarollo L; Dupuy AJ
Genesis; 2012 Feb; 50(2):112-8. PubMed ID: 21898766
[TBL] [Abstract][Full Text] [Related]
20. The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group.
Larson Gedman A; Chen Q; Kugel Desmoulin S; Ge Y; LaFiura K; Haska CL; Cherian C; Devidas M; Linda SB; Taub JW; Matherly LH
Leukemia; 2009 Aug; 23(8):1417-25. PubMed ID: 19340001
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]