153 related articles for article (PubMed ID: 21094046)
1. Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor.
Yao Z; Xu Y; Zhang M; Jiang S; Nicklaus MC; Liao C
Bioorg Med Chem Lett; 2011 Jan; 21(1):475-8. PubMed ID: 21094046
[TBL] [Abstract][Full Text] [Related]
2. Comparative study of human steroid 5alpha-reductase isoforms in prostate and female breast skin tissues: sensitivity to inhibition by finasteride and epristeride.
Ranjan M; Diffley P; Stephen G; Price D; Walton TJ; Newton RP
Life Sci; 2002 May; 71(2):115-26. PubMed ID: 12031682
[TBL] [Abstract][Full Text] [Related]
3. Effects of competitive and noncompetitive 5α-reductase inhibitors on serum and intra-prostatic androgens in beagle dogs.
Zhao XF; Yang Y; Wang W; Qiu Z; Zhang P; Wang B
Chin Med J (Engl); 2013 Feb; 126(4):711-5. PubMed ID: 23422194
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and bioactivity of new Finasteride conjugate.
Shuang Z; Jiazhen W; Lijuan Y; Zhuo L; Dahai Y; Jinfeng L; Jing Y; Yongtao L; En-Si W; Xuexun F
Bioorg Med Chem Lett; 2011 Jun; 21(11):3439-42. PubMed ID: 21515045
[TBL] [Abstract][Full Text] [Related]
5. Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5alpha-reductase II.
Pais P
Adv Ther; 2010 Aug; 27(8):555-63. PubMed ID: 20623347
[TBL] [Abstract][Full Text] [Related]
6. A review on steroidal 5α-reductase inhibitors for treatment of benign prostatic hyperplasia.
Sun J; Xiang H; Yang LL; Chen JB
Curr Med Chem; 2011; 18(23):3576-89. PubMed ID: 21756226
[TBL] [Abstract][Full Text] [Related]
7. CGP 53153: a new potent inhibitor of 5alpha-reductase.
Häusler A; Allegrini PR; Biollaz M; Batzl C; Scheidegger E; Bhatnagar AS
J Steroid Biochem Mol Biol; 1996 Feb; 57(3-4):187-95. PubMed ID: 8645628
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists.
Lao K; Sun J; Wang C; Wang Y; You Q; Xiao H; Xiang H
Bioorg Med Chem Lett; 2017 Sep; 27(17):4212-4217. PubMed ID: 28757062
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and 5α-reductase inhibitory activity of C₂₁ steroids having 1,4-diene or 4,6-diene 20-ones and 4-azasteroid 20-oximes.
Kim S; Kim YU; Ma E
Molecules; 2011 Dec; 17(1):355-68. PubMed ID: 22210173
[TBL] [Abstract][Full Text] [Related]
10. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5alpha-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat.
Stuart JD; Lee FW; Simpson Noel D; Kadwell SH; Overton LK; Hoffman CR; Kost TA; Tippin TK; Yeager RL; Batchelor KW; Bramson HN
Biochem Pharmacol; 2001 Oct; 62(7):933-42. PubMed ID: 11543729
[TBL] [Abstract][Full Text] [Related]
11. The effects of progesterone, 4,16-androstadien-3-one and MK-434 on the kinetics of pig testis microsomal testosterone-4-ene-5alpha-reductase activity.
Cooke GM; Pothier F; Murphy BD
J Steroid Biochem Mol Biol; 1997 Mar; 60(5-6):353-9. PubMed ID: 9219928
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2.
Lao K; Sun J; Wang C; Lyu W; Zhou B; Zhao R; Xu Q; You Q; Xiang H
Steroids; 2017 Aug; 124():29-34. PubMed ID: 28549802
[TBL] [Abstract][Full Text] [Related]
13. Steroidal pyrazolines and pyrazoles as potential 5α-reductase inhibitors: synthesis and biological evaluation.
Banday AH; Shameem SA; Jeelani S
Steroids; 2014 Dec; 92():13-9. PubMed ID: 25278254
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors.
Karnsomwan W; Netcharoensirisuk P; Rungrotmongkol T; De-Eknamkul W; Chamni S
Chem Pharm Bull (Tokyo); 2017; 65(3):253-260. PubMed ID: 28250347
[TBL] [Abstract][Full Text] [Related]
15. Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target.
Giatti S; Di Domizio A; Diviccaro S; Falvo E; Caruso D; Contini A; Melcangi RC
J Med Chem; 2021 Apr; 64(8):4553-4566. PubMed ID: 33843213
[TBL] [Abstract][Full Text] [Related]
16. Steroid 5α-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders.
Paba S; Frau R; Godar SC; Devoto P; Marrosu F; Bortolato M
Curr Pharm Des; 2011; 17(2):151-67. PubMed ID: 21361868
[TBL] [Abstract][Full Text] [Related]
17. Dihydrotestosterone and the concept of 5alpha-reductase inhibition in human benign prostatic hyperplasia.
Bartsch G; Rittmaster RS; Klocker H
Eur Urol; 2000 Apr; 37(4):367-80. PubMed ID: 10765065
[TBL] [Abstract][Full Text] [Related]
18. Finasteride is the main inhibitor of 5alpha-reductase activity in microdissected dermal papillae of human hair follicles.
Hoffmann R; Happle R
Arch Dermatol Res; 1999; 291(2-3):100-3. PubMed ID: 10195397
[No Abstract] [Full Text] [Related]
19. The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating.
Frau R; Mosher LJ; Bini V; Pillolla G; Pes R; Saba P; Fanni S; Devoto P; Bortolato M
Psychoneuroendocrinology; 2016 Jan; 63():59-67. PubMed ID: 26415119
[TBL] [Abstract][Full Text] [Related]
20. Effect of a novel steroid (PM-9) on the inhibition of 5alpha-reductase present in Penicillium crustosum broths.
Flores E; Cabeza M; Quiroz A; Bratoeff E; García G; Ramírez E
Steroids; 2003 Mar; 68(3):271-5. PubMed ID: 12628690
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]