BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 21094904)

  • 1. Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.
    Leech CA; Chepurny OG; Holz GG
    Vitam Horm; 2010; 84():279-302. PubMed ID: 21094904
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.
    Dzhura I; Chepurny OG; Leech CA; Roe MW; Dzhura E; Xu X; Lu Y; Schwede F; Genieser HG; Smrcka AV; Holz GG
    Islets; 2011; 3(3):121-8. PubMed ID: 21478675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.
    Zhang M; Robitaille M; Showalter AD; Huang X; Liu Y; Bhattacharjee A; Willard FS; Han J; Froese S; Wei L; Gaisano HY; Angers S; Sloop KW; Dai FF; Wheeler MB
    Mol Cell Proteomics; 2014 Nov; 13(11):3049-62. PubMed ID: 25044020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucagon-like peptide-1 enhances glucokinase activity in pancreatic β-cells through the association of Epac2 with Rim2 and Rab3A.
    Park JH; Kim SJ; Park SH; Son DG; Bae JH; Kim HK; Han J; Song DK
    Endocrinology; 2012 Feb; 153(2):574-82. PubMed ID: 22147008
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell.
    Holz GG
    Diabetes; 2004 Jan; 53(1):5-13. PubMed ID: 14693691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucagon-like peptide 1 potentiates glucotoxicity-diminished insulin secretion via stimulation of cAMP-PKA signaling in INS-1E cells and mouse islets.
    Luo G; Kong X; Lu L; Xu X; Wang H; Ma X
    Int J Biochem Cell Biol; 2013 Feb; 45(2):483-90. PubMed ID: 23220045
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon.
    Cabrera O; Ficorilli J; Shaw J; Echeverri F; Schwede F; Chepurny OG; Leech CA; Holz GG
    J Biol Chem; 2022 Feb; 298(2):101484. PubMed ID: 34896391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.
    Dzhura I; Chepurny OG; Kelley GG; Leech CA; Roe MW; Dzhura E; Afshari P; Malik S; Rindler MJ; Xu X; Lu Y; Smrcka AV; Holz GG
    J Physiol; 2010 Dec; 588(Pt 24):4871-89. PubMed ID: 21041529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure.
    Kim M; Platt MJ; Shibasaki T; Quaggin SE; Backx PH; Seino S; Simpson JA; Drucker DJ
    Nat Med; 2013 May; 19(5):567-75. PubMed ID: 23542788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells.
    Lee YS; Jun HS
    Metabolism; 2014 Jan; 63(1):9-19. PubMed ID: 24140094
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose.
    Zhang Y; Han C; Zhu W; Yang G; Peng X; Mehta S; Zhang J; Chen L; Liu Y
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells.
    Holz GG
    Horm Metab Res; 2004; 36(11-12):787-94. PubMed ID: 15655710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor.
    Yang Y; Tong Y; Gong M; Lu Y; Wang C; Zhou M; Yang Q; Mao T; Tong N
    Cell Signal; 2014 Feb; 26(2):268-78. PubMed ID: 24269940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells.
    Leech CA; Holz GG; Chepurny O; Habener JF
    Biochem Biophys Res Commun; 2000 Nov; 278(1):44-7. PubMed ID: 11071853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Absence of the glucagon-like peptide-1 receptor does not affect the metabolic phenotype of mice with liver-specific G(s)α deficiency.
    Chen M; Mema E; Kelleher J; Nemechek N; Berger A; Wang J; Xie T; Gavrilova O; Drucker DJ; Weinstein LS
    Endocrinology; 2011 Sep; 152(9):3343-50. PubMed ID: 21771891
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation.
    Kelly P; Bailey CL; Fueger PT; Newgard CB; Casey PJ; Kimple ME
    J Biol Chem; 2010 May; 285(21):15777-85. PubMed ID: 20339002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly Activated by Cyclic AMP 1/Ras-Related Protein 1 Axis.
    Aoyama M; Kawase H; Bando YK; Monji A; Murohara T
    Circ Heart Fail; 2016 Jan; 9(1):e002081. PubMed ID: 26721911
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets.
    Veluthakal R; Chepurny OG; Leech CA; Schwede F; Holz GG; Thurmond DC
    Diabetes; 2018 Oct; 67(10):1999-2011. PubMed ID: 29986926
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucagon-like peptide 1-potentiated insulin secretion and proliferation of pancreatic β-cells.
    Ma X; Guan Y; Hua X
    J Diabetes; 2014 Sep; 6(5):394-402. PubMed ID: 24725840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential.
    Gromada J; Brock B; Schmitz O; Rorsman P
    Basic Clin Pharmacol Toxicol; 2004 Dec; 95(6):252-62. PubMed ID: 15569269
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.