316 related articles for article (PubMed ID: 21095131)
1. 3-Arylisoquinolines as novel topoisomerase I inhibitors.
Khadka DB; Cho WJ
Bioorg Med Chem; 2011 Jan; 19(2):724-34. PubMed ID: 21095131
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors.
Khadka DB; Le QM; Yang SH; Van HT; Le TN; Cho SH; Kwon Y; Lee KT; Lee ES; Cho WJ
Bioorg Med Chem; 2011 Mar; 19(6):1924-9. PubMed ID: 21353568
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study.
Van HT; Khadka DB; Yang SH; Le TN; Cho SH; Zhao C; Lee IS; Kwon Y; Lee KT; Kim YC; Cho WJ
Bioorg Med Chem; 2011 Sep; 19(18):5311-20. PubMed ID: 21873069
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.
Ahn G; Schifano-Faux N; Goossens JF; Baldeyrou B; Couture A; Grandclaudon P; Lansiaux A; Ryckebusch A
Bioorg Med Chem Lett; 2011 Apr; 21(8):2259-63. PubMed ID: 21439821
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
Zhu L; Zhang X; Lei N; Liu W; Miao Z; Zhuang C; Sheng C; Guo W; Dong G; Yao J; Cheng P; Zhang W
Chem Biodivers; 2012 Jun; 9(6):1084-94. PubMed ID: 22700227
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
8. Suzuki coupling based synthesis and in vitro cytotoxic evaluation of 7-heteroaryl-substituted camptothecin analogs.
Wang L; Huang Y; Zhang J; Tong L; Chen Y; Lu W; Huang Q
Bioorg Med Chem Lett; 2014 Mar; 24(6):1597-9. PubMed ID: 24529870
[TBL] [Abstract][Full Text] [Related]
9. Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents.
Gao C; Liu F; Luan X; Tan C; Liu H; Xie Y; Jin Y; Jiang Y
Bioorg Med Chem; 2010 Nov; 18(21):7507-14. PubMed ID: 20863710
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids.
Fox BM; Xiao X; Antony S; Kohlhagen G; Pommier Y; Staker BL; Stewart L; Cushman M
J Med Chem; 2003 Jul; 46(15):3275-82. PubMed ID: 12852757
[TBL] [Abstract][Full Text] [Related]
11. Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition.
Khadka DB; Woo H; Yang SH; Zhao C; Jin Y; Le TN; Kwon Y; Cho WJ
Eur J Med Chem; 2015 Mar; 92():583-607. PubMed ID: 25613224
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
[TBL] [Abstract][Full Text] [Related]
14. Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors.
Lee SH; Van HT; Yang SH; Lee KT; Kwon Y; Cho WJ
Bioorg Med Chem Lett; 2009 May; 19(9):2444-7. PubMed ID: 19345580
[TBL] [Abstract][Full Text] [Related]
15. Structural modification of 3-arylisoquinolines to isoindolo[2,1-b]isoquinolinones for the development of novel topoisomerase 1 inhibitors with molecular docking study.
Van HT; Cho WJ
Bioorg Med Chem Lett; 2009 May; 19(9):2551-4. PubMed ID: 19328687
[TBL] [Abstract][Full Text] [Related]
16. New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors.
Sheng C; Miao Z; Zhang W
Curr Med Chem; 2011; 18(28):4389-409. PubMed ID: 21861816
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings.
Nagarajan M; Morrell A; Fort BC; Meckley MR; Antony S; Kohlhagen G; Pommier Y; Cushman M
J Med Chem; 2004 Nov; 47(23):5651-61. PubMed ID: 15509164
[TBL] [Abstract][Full Text] [Related]
18. Antitumor agents 294. Novel E-ring-modified camptothecin-4β-anilino-4'-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents.
Ye D; Shi Q; Leung CH; Kim SW; Park SY; Gullen EA; Jiang ZL; Zhu H; Morris-Natschke SL; Cheng YC; Lee KH
Bioorg Med Chem; 2012 Jul; 20(14):4489-94. PubMed ID: 22698783
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
[TBL] [Abstract][Full Text] [Related]
20. Neurotoxic activity of a topoisomerase-I inhibitor, camptothecin, in cultured cerebellar granule neurons.
Uday Bhanu M; Kondapi AK
Neurotoxicology; 2010 Dec; 31(6):730-7. PubMed ID: 20600288
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
