These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

398 related articles for article (PubMed ID: 21095582)

  • 1. mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.
    Cam H; Easton JB; High A; Houghton PJ
    Mol Cell; 2010 Nov; 40(4):509-20. PubMed ID: 21095582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of mammalian target of rapamycin complex 1 (mTORC1) by hypoxia: causes and consequences.
    Cam H; Houghton PJ
    Target Oncol; 2011 Jun; 6(2):95-102. PubMed ID: 21499767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
    Alexander A; Cai SL; Kim J; Nanez A; Sahin M; MacLean KH; Inoki K; Guan KL; Shen J; Person MD; Kusewitt D; Mills GB; Kastan MB; Walker CL
    Proc Natl Acad Sci U S A; 2010 Mar; 107(9):4153-8. PubMed ID: 20160076
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemotherapy-mediated p53-dependent DNA damage response in clear cell renal cell carcinoma: role of the mTORC1/2 and hypoxia-inducible factor pathways.
    Selvarajah J; Nathawat K; Moumen A; Ashcroft M; Carroll VA
    Cell Death Dis; 2013 Oct; 4(10):e865. PubMed ID: 24136229
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of hypoxia-inducible factor 1α (HIF-1α) by tirapazamine is dependent on eIF2α phosphorylation rather than the mTORC1/4E-BP1 pathway.
    Zhang J; Cao J; Weng Q; Wu R; Yan Y; Jing H; Zhu H; He Q; Yang B
    PLoS One; 2010 Nov; 5(11):e13910. PubMed ID: 21085474
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
    D'Souza AD; Parish IA; McKay SE; Kaech SM; Shadel GS
    Am J Pathol; 2011 Jun; 178(6):2740-51. PubMed ID: 21641396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
    Wolff NC; Vega-Rubin-de-Celis S; Xie XJ; Castrillon DH; Kabbani W; Brugarolas J
    Mol Cell Biol; 2011 May; 31(9):1870-84. PubMed ID: 21383064
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM engages the TSC2/mTORC1 signaling node to regulate autophagy.
    Alexander A; Kim J; Walker CL
    Autophagy; 2010 Jul; 6(5):672-3. PubMed ID: 20581436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
    Tripathi DN; Chowdhury R; Trudel LJ; Tee AR; Slack RS; Walker CL; Wogan GN
    Proc Natl Acad Sci U S A; 2013 Aug; 110(32):E2950-7. PubMed ID: 23878245
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways.
    Rodríguez-Jiménez FJ; Moreno-Manzano V; Mateos-Gregorio P; Royo I; Erceg S; Murguia JR; Sánchez-Puelles JM
    Cell Cycle; 2010 Jul; 9(14):2803-13. PubMed ID: 20676050
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest.
    Hammond EM; Green SL; Giaccia AJ
    Mutat Res; 2003 Nov; 532(1-2):205-13. PubMed ID: 14643437
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.
    Liu Q; Kirubakaran S; Hur W; Niepel M; Westover K; Thoreen CC; Wang J; Ni J; Patricelli MP; Vogel K; Riddle S; Waller DL; Traynor R; Sanda T; Zhao Z; Kang SA; Zhao J; Look AT; Sorger PK; Sabatini DM; Gray NS
    J Biol Chem; 2012 Mar; 287(13):9742-9752. PubMed ID: 22223645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The mTOR pathway negatively controls ATM by up-regulating miRNAs.
    Shen C; Houghton PJ
    Proc Natl Acad Sci U S A; 2013 Jul; 110(29):11869-74. PubMed ID: 23818585
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner.
    Gibson SL; Bindra RS; Glazer PM
    Cancer Res; 2005 Dec; 65(23):10734-41. PubMed ID: 16322218
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome.
    Shackelford DB; Vasquez DS; Corbeil J; Wu S; Leblanc M; Wu CL; Vera DR; Shaw RJ
    Proc Natl Acad Sci U S A; 2009 Jul; 106(27):11137-42. PubMed ID: 19541609
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia links ATR and p53 through replication arrest.
    Hammond EM; Denko NC; Dorie MJ; Abraham RT; Giaccia AJ
    Mol Cell Biol; 2002 Mar; 22(6):1834-43. PubMed ID: 11865061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TGF-β/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1α expression.
    Rozen-Zvi B; Hayashida T; Hubchak SC; Hanna C; Platanias LC; Schnaper HW
    Am J Physiol Renal Physiol; 2013 Aug; 305(4):F485-94. PubMed ID: 23761672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Checking in on hypoxia/reoxygenation.
    Freiberg RA; Krieg AJ; Giaccia AJ; Hammond EM
    Cell Cycle; 2006 Jun; 5(12):1304-7. PubMed ID: 16760660
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Post-translational regulation of mTOR complex 1 in hypoxia and reoxygenation.
    Tan CY; Hagen T
    Cell Signal; 2013 May; 25(5):1235-44. PubMed ID: 23416465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATM activation and signaling under hypoxic conditions.
    Bencokova Z; Kaufmann MR; Pires IM; Lecane PS; Giaccia AJ; Hammond EM
    Mol Cell Biol; 2009 Jan; 29(2):526-37. PubMed ID: 18981219
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.