BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 21102522)

  • 1. Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo.
    Algire C; Amrein L; Bazile M; David S; Zakikhani M; Pollak M
    Oncogene; 2011 Mar; 30(10):1174-82. PubMed ID: 21102522
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth.
    Algire C; Zakikhani M; Blouin MJ; Shuai JH; Pollak M
    Endocr Relat Cancer; 2008 Sep; 15(3):833-9. PubMed ID: 18469156
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.
    Algire C; Amrein L; Zakikhani M; Panasci L; Pollak M
    Endocr Relat Cancer; 2010 Jun; 17(2):351-60. PubMed ID: 20228137
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
    Lin CC; Yeh HH; Huang WL; Yan JJ; Lai WW; Su WP; Chen HH; Su WC
    Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth.
    Rocha GZ; Dias MM; Ropelle ER; Osório-Costa F; Rossato FA; Vercesi AE; Saad MJ; Carvalheira JB
    Clin Cancer Res; 2011 Jun; 17(12):3993-4005. PubMed ID: 21543517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.
    Zu Y; Liu L; Lee MY; Xu C; Liang Y; Man RY; Vanhoutte PM; Wang Y
    Circ Res; 2010 Apr; 106(8):1384-93. PubMed ID: 20203304
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells.
    Zakikhani M; Blouin MJ; Piura E; Pollak MN
    Breast Cancer Res Treat; 2010 Aug; 123(1):271-9. PubMed ID: 20135346
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.
    Ben Sahra I; Laurent K; Loubat A; Giorgetti-Peraldi S; Colosetti P; Auberger P; Tanti JF; Le Marchand-Brustel Y; Bost F
    Oncogene; 2008 Jun; 27(25):3576-86. PubMed ID: 18212742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.
    Kim YD; Park KG; Lee YS; Park YY; Kim DK; Nedumaran B; Jang WG; Cho WJ; Ha J; Lee IK; Lee CH; Choi HS
    Diabetes; 2008 Feb; 57(2):306-14. PubMed ID: 17909097
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LKB1: a sweet side to Peutz-Jeghers syndrome?
    Carling D
    Trends Mol Med; 2006 Apr; 12(4):144-7. PubMed ID: 16530014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase.
    Guo Q; Liu Z; Jiang L; Liu M; Ma J; Yang C; Han L; Nan K; Liang X
    Mol Med Rep; 2016 Mar; 13(3):2590-6. PubMed ID: 26847819
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Catechin-induced activation of the LKB1/AMP-activated protein kinase pathway.
    Murase T; Misawa K; Haramizu S; Hase T
    Biochem Pharmacol; 2009 Jul; 78(1):78-84. PubMed ID: 19447226
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling.
    Calvert JW; Gundewar S; Jha S; Greer JJ; Bestermann WH; Tian R; Lefer DJ
    Diabetes; 2008 Mar; 57(3):696-705. PubMed ID: 18083782
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth.
    Buzzai M; Jones RG; Amaravadi RK; Lum JJ; DeBerardinis RJ; Zhao F; Viollet B; Thompson CB
    Cancer Res; 2007 Jul; 67(14):6745-52. PubMed ID: 17638885
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase.
    Huypens P; Quartier E; Pipeleers D; Van de Casteele M
    Eur J Pharmacol; 2005 Aug; 518(2-3):90-5. PubMed ID: 16039647
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.
    Li NS; Zou JR; Lin H; Ke R; He XL; Xiao L; Huang D; Luo L; Lv N; Luo Z
    Tumour Biol; 2016 Jun; 37(6):8249-58. PubMed ID: 26718214
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression.
    Cao Y; Li H; Liu H; Zheng C; Ji H; Liu X
    Cell Res; 2010 Jan; 20(1):99-108. PubMed ID: 20029389
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells.
    Dowling RJ; Zakikhani M; Fantus IG; Pollak M; Sonenberg N
    Cancer Res; 2007 Nov; 67(22):10804-12. PubMed ID: 18006825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of metformin on bovine granulosa cells steroidogenesis: possible involvement of adenosine 5' monophosphate-activated protein kinase (AMPK).
    Tosca L; Chabrolle C; Uzbekova S; Dupont J
    Biol Reprod; 2007 Mar; 76(3):368-78. PubMed ID: 17123942
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metformin and cancer.
    Vallianou NG; Evangelopoulos A; Kazazis C
    Rev Diabet Stud; 2013; 10(4):228-35. PubMed ID: 24841876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.