BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

567 related articles for article (PubMed ID: 21103969)

  • 1. Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy.
    Nies AT; Koepsell H; Damme K; Schwab M
    Handb Exp Pharmacol; 2011; (201):105-67. PubMed ID: 21103969
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins.
    Neul C; Hofmann U; Schaeffeler E; Winter S; Klein K; Giacomini KM; Eichelbaum M; Schwab M; Nies AT
    Br J Pharmacol; 2021 Mar; 178(6):1459-1474. PubMed ID: 33434947
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
    Motohashi H; Inui K
    AAPS J; 2013 Apr; 15(2):581-8. PubMed ID: 23435786
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Update on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced
    Koepsell H
    Expert Opin Drug Metab Toxicol; 2021 Jun; 17(6):635-653. PubMed ID: 33896325
    [No Abstract]   [Full Text] [Related]  

  • 5. Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule.
    Lee WK; Reichold M; Edemir B; Ciarimboli G; Warth R; Koepsell H; Thévenod F
    Am J Physiol Renal Physiol; 2009 Jun; 296(6):F1504-13. PubMed ID: 19357179
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic and Epigenetic Regulation of Organic Cation Transporters.
    Kölz C; Schaeffeler E; Schwab M; Nies AT
    Handb Exp Pharmacol; 2021; 266():81-100. PubMed ID: 33674913
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics.
    Staud F; Cerveny L; Ahmadimoghaddam D; Ceckova M
    Int J Biochem Cell Biol; 2013 Sep; 45(9):2007-11. PubMed ID: 23831838
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics.
    Damme K; Nies AT; Schaeffeler E; Schwab M
    Drug Metab Rev; 2011 Nov; 43(4):499-523. PubMed ID: 21923552
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).
    Terada T; Inui K
    Biochem Pharmacol; 2008 May; 75(9):1689-96. PubMed ID: 18262170
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tissue distribution and ontogeny of organic cation transporters in mice.
    Alnouti Y; Petrick JS; Klaassen CD
    Drug Metab Dispos; 2006 Mar; 34(3):477-82. PubMed ID: 16381671
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection.
    Jung N; Lehmann C; Rubbert A; Knispel M; Hartmann P; van Lunzen J; Stellbrink HJ; Faetkenheuer G; Taubert D
    Drug Metab Dispos; 2008 Aug; 36(8):1616-23. PubMed ID: 18490433
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin.
    Tsuda M; Terada T; Mizuno T; Katsura T; Shimakura J; Inui K
    Mol Pharmacol; 2009 Jun; 75(6):1280-6. PubMed ID: 19332510
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of organic cation transporters in drug-drug interaction.
    Koepsell H
    Expert Opin Drug Metab Toxicol; 2015; 11(10):1619-33. PubMed ID: 26206523
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tropane alkaloids as substrates and inhibitors of human organic cation transporters of the SLC22 (OCT) and the SLC47 (MATE) families.
    Chen J; Brockmöller J; Seitz T; König J; Chen X; Tzvetkov MV
    Biol Chem; 2017 Feb; 398(2):237-249. PubMed ID: 27676604
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).
    Li Q; Guo D; Dong Z; Zhang W; Zhang L; Huang SM; Polli JE; Shu Y
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):100-9. PubMed ID: 24001450
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.
    Omote H; Hiasa M; Matsumoto T; Otsuka M; Moriyama Y
    Trends Pharmacol Sci; 2006 Nov; 27(11):587-93. PubMed ID: 16996621
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice.
    Schmitt A; Mössner R; Gossmann A; Fischer IG; Gorboulev V; Murphy DL; Koepsell H; Lesch KP
    J Neurosci Res; 2003 Mar; 71(5):701-9. PubMed ID: 12584728
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity.
    Nakamura T; Yonezawa A; Hashimoto S; Katsura T; Inui K
    Biochem Pharmacol; 2010 Dec; 80(11):1762-7. PubMed ID: 20813096
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine.
    Ito S; Kusuhara H; Kuroiwa Y; Wu C; Moriyama Y; Inoue K; Kondo T; Yuasa H; Nakayama H; Horita S; Sugiyama Y
    J Pharmacol Exp Ther; 2010 Apr; 333(1):341-50. PubMed ID: 20065018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain.
    Amphoux A; Vialou V; Drescher E; Brüss M; Mannoury La Cour C; Rochat C; Millan MJ; Giros B; Bönisch H; Gautron S
    Neuropharmacology; 2006 Jun; 50(8):941-52. PubMed ID: 16581093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.