BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

570 related articles for article (PubMed ID: 21103969)

  • 41. Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.
    Te Brake LH; van den Heuvel JJ; Buaben AO; van Crevel R; Bilos A; Russel FG; Aarnoutse RE; Koenderink JB
    Antimicrob Agents Chemother; 2016 Dec; 60(12):7105-7114. PubMed ID: 27645247
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family).
    Yonezawa A; Masuda S; Yokoo S; Katsura T; Inui K
    J Pharmacol Exp Ther; 2006 Nov; 319(2):879-86. PubMed ID: 16914559
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Divergent Regulation of OCT and MATE Drug Transporters by Cadmium Exposure.
    Yang H; Zhou S; Guo D; Obianom ON; Li Q; Shu Y
    Pharmaceutics; 2021 Apr; 13(4):. PubMed ID: 33924306
    [TBL] [Abstract][Full Text] [Related]  

  • 44. The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition.
    Zazuli Z; Duin NJCB; Jansen K; Vijverberg SJH; Maitland-van der Zee AH; Masereeuw R
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32927790
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants.
    Fujita T; Urban TJ; Leabman MK; Fujita K; Giacomini KM
    J Pharm Sci; 2006 Jan; 95(1):25-36. PubMed ID: 16307453
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH.
    Blanc Mettral J; Faller N; Cruchon S; Sottas L; Buclin T; Schild L; Choong E; Nahimana A; Decosterd LA
    Drug Metab Lett; 2019; 13(2):102-110. PubMed ID: 30734690
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Transporters as a determinant of drug clearance and tissue distribution.
    Shitara Y; Horie T; Sugiyama Y
    Eur J Pharm Sci; 2006 Apr; 27(5):425-46. PubMed ID: 16488580
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Polyspecific organic cation transporters and their biomedical relevance in kidney.
    Koepsell H
    Curr Opin Nephrol Hypertens; 2013 Sep; 22(5):533-8. PubMed ID: 23852330
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate).
    Ceckova M; Reznicek J; Deutsch B; Fromm MF; Staud F
    PLoS One; 2018; 13(8):e0202706. PubMed ID: 30114293
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.
    Shen H; Liu T; Jiang H; Titsch C; Taylor K; Kandoussi H; Qiu X; Chen C; Sukrutharaj S; Kuit K; Mintier G; Krishnamurthy P; Fancher RM; Zeng J; Rodrigues AD; Marathe P; Lai Y
    Drug Metab Dispos; 2016 Feb; 44(2):238-49. PubMed ID: 26608080
    [TBL] [Abstract][Full Text] [Related]  

  • 51. PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.
    Kato Y; Sai Y; Yoshida K; Watanabe C; Hirata T; Tsuji A
    Mol Pharmacol; 2005 Mar; 67(3):734-43. PubMed ID: 15523054
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications.
    Koepsell H; Lips K; Volk C
    Pharm Res; 2007 Jul; 24(7):1227-51. PubMed ID: 17473959
    [TBL] [Abstract][Full Text] [Related]  

  • 53. A Whole-Body Physiologically Based Pharmacokinetic Model Characterizing Interplay of OCTs and MATEs in Intestine, Liver and Kidney to Predict Drug-Drug Interactions of Metformin with Perpetrators.
    Yang Y; Zhang Z; Li P; Kong W; Liu X; Liu L
    Pharmaceutics; 2021 May; 13(5):. PubMed ID: 34064886
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Association of the SLC22A1, SLC22A2, and SLC22A3 genes encoding organic cation transporters with diabetic nephropathy and hypertension.
    Sallinen R; Kaunisto MA; Forsblom C; Thomas M; Fagerudd J; Pettersson-Fernholm K; Groop PH; Wessman M;
    Ann Med; 2010 May; 42(4):296-304. PubMed ID: 20429798
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Involvement of organic cation transporters in the clearance and milk secretion of thiamine in mice.
    Kato K; Moriyama C; Ito N; Zhang X; Hachiuma K; Hagima N; Iwata K; Yamaguchi J; Maeda K; Ito K; Suzuki H; Sugiyama Y; Kusuhara H
    Pharm Res; 2015 Jul; 32(7):2192-204. PubMed ID: 25701312
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Cationic Compounds with SARS-CoV-2 Antiviral Activity and Their Interaction with Organic Cation Transporter/Multidrug and Toxin Extruder Secretory Transporters.
    Martinez-Guerrero L; Zhang X; Zorn KM; Ekins S; Wright SH
    J Pharmacol Exp Ther; 2021 Oct; 379(1):96-107. PubMed ID: 34253645
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics.
    Higgins JW; Bedwell DW; Zamek-Gliszczynski MJ
    Drug Metab Dispos; 2012 Jun; 40(6):1170-7. PubMed ID: 22407892
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter in the placenta and fetal tissues: expression profile and fetus protective role at different stages of gestation.
    Ahmadimoghaddam D; Zemankova L; Nachtigal P; Dolezelova E; Neumanova Z; Cerveny L; Ceckova M; Kacerovský M; Micuda S; Staud F
    Biol Reprod; 2013 Mar; 88(3):55. PubMed ID: 23303678
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Evaluation and Quantitative Prediction of Renal Transporter-Mediated Drug-Drug Interactions.
    Feng B; Varma MV
    J Clin Pharmacol; 2016 Jul; 56 Suppl 7():S110-21. PubMed ID: 27385169
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors.
    Kato Y; Watanabe C; Tsuji A
    Eur J Pharm Sci; 2006 Apr; 27(5):487-500. PubMed ID: 16376527
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.