BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 21105783)

  • 1. Characterization of metabolites and human P450 isoforms involved in the microsomal metabolism of mesaconitine.
    Ye L; Tang L; Gong Y; Lv C; Zheng Z; Jiang Z; Liu Z
    Xenobiotica; 2011 Jan; 41(1):46-58. PubMed ID: 21105783
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine.
    Wang Y; Wang S; Liu Y; Yan L; Dou G; Gao Y
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Dec; 844(2):292-300. PubMed ID: 16949890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
    Filppula AM; Laitila J; Neuvonen PJ; Backman JT
    Drug Metab Dispos; 2011 May; 39(5):904-11. PubMed ID: 21289076
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes.
    Tang L; Ye L; Lv C; Zheng Z; Gong Y; Liu Z
    Toxicol Lett; 2011 Apr; 202(1):47-54. PubMed ID: 21277363
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species.
    Ye L; Wang T; Yang C; Tang L; Zhou J; Lv C; Gong Y; Jiang Z; Liu Z
    Toxicol Lett; 2011 Jul; 204(1):81-91. PubMed ID: 21550385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Metabolites and metabolic pathways of mesaconitine in rat liver microsomal investigated by using UPLC-MS/MS method in vitro].
    Bi YF; Liu S; Zhang RX; Song FR; Liu ZQ
    Yao Xue Xue Bao; 2013 Dec; 48(12):1823-8. PubMed ID: 24689241
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C; Benyamina A; Llorca PM; Baylé F; Bromet N; Massiere F; Garay RP; Hameg A
    Eur J Pharm Sci; 2007 Dec; 32(4-5):357-66. PubMed ID: 17951033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro metabolism of magnolin and characterization of cytochrome P450 enzymes responsible for its metabolism in human liver microsomes.
    Kim DK; Liu KH; Jeong JH; Ji HY; Oh SR; Lee HK; Lee HS
    Xenobiotica; 2011 May; 41(5):358-71. PubMed ID: 21294626
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.
    Prueksaritanont T; Gorham LM; Ma B; Liu L; Yu X; Zhao JJ; Slaughter DE; Arison BH; Vyas KP
    Drug Metab Dispos; 1997 Oct; 25(10):1191-9. PubMed ID: 9321523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of a new H+/K+-ATPase inhibitor KR-60436.
    Ji HY; Lee HW; Kim HH; Choi JK; Lee HS
    Toxicol Lett; 2005 Jan; 155(1):103-14. PubMed ID: 15585365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes.
    Kim KA; Park JY
    Drug Metab Dispos; 2003 Sep; 31(9):1090-2. PubMed ID: 12920163
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW; Dean DC; Miller RR; Rasmusson GH; Chiu SH
    Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
    Prakash C; Wang W; O'Connell T; Johnson KA
    Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450.
    Koga N; Ohta C; Kato Y; Haraguchi K; Endo T; Ogawa K; Ohta H; Yano M
    Xenobiotica; 2011 Nov; 41(11):927-33. PubMed ID: 21726170
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) by human liver microsomes: characterization of metabolic pathways and of cytochrome P450 isoforms involved.
    Baek MS; Kim JY; Myung SW; Yim YH; Jeong JH; Kim DH
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):381-8. PubMed ID: 11259320
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
    Fang J; McKay G; Song J; Remillrd A; Li X; Midha K
    Drug Metab Dispos; 2001 Dec; 29(12):1638-43. PubMed ID: 11717183
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028.
    Kim H; Yoon YJ; Kim H; Kang S; Cheon HG; Yoo SE; Shin JG; Liu KH
    Toxicol Lett; 2006 Oct; 166(2):105-14. PubMed ID: 16857327
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of human CYP2C8 and CYP2C9 variants in pioglitazone metabolism in vitro.
    Muschler E; Lal J; Jetter A; Rattay A; Zanger U; Zadoyan G; Fuhr U; Kirchheiner J
    Basic Clin Pharmacol Toxicol; 2009 Dec; 105(6):374-9. PubMed ID: 19614891
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
    Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
    Eur Neuropsychopharmacol; 2004 May; 14(3):199-208. PubMed ID: 15056479
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.