These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

619 related articles for article (PubMed ID: 21106277)

  • 1. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
    Pontiki E; Hadjipavlou-Litina D; Litinas K; Nicolotti O; Carotti A
    Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
    Li Y; Chen SH; Ou TM; Tan JH; Li D; Gu LQ; Huang ZS
    Bioorg Med Chem; 2011 Mar; 19(6):2074-83. PubMed ID: 21349729
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.
    Melagraki G; Afantitis A; Igglessi-Markopoulou O; Detsi A; Koufaki M; Kontogiorgis C; Hadjipavlou-Litina DJ
    Eur J Med Chem; 2009 Jul; 44(7):3020-6. PubMed ID: 19232783
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
    Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
    Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
    Moreau A; Chen QH; Praveen Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7716-27. PubMed ID: 16931030
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.
    Eleftheriou P; Geronikaki A; Hadjipavlou-Litina D; Vicini P; Filz O; Filimonov D; Poroikov V; Chaudhaery SS; Roy KK; Saxena AK
    Eur J Med Chem; 2012 Jan; 47(1):111-24. PubMed ID: 22119153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K; Özkanlı F; Jain S; Rao PP; Velázquez-Martínez CA
    Bioorg Med Chem; 2012 May; 20(9):2912-22. PubMed ID: 22475926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design of more potent squalene synthase inhibitors with multiple activities.
    Kourounakis AP; Matralis AN; Nikitakis A
    Bioorg Med Chem; 2010 Nov; 18(21):7402-12. PubMed ID: 20888243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and pharmacochemical evaluation of novel aryl-acetic acid inhibitors of lipoxygenase, antioxidants, and anti-inflammatory agents.
    Pontiki E; Hadjipavlou-Litina D
    Bioorg Med Chem; 2007 Sep; 15(17):5819-27. PubMed ID: 17604175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aspirin analogues as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, nitric oxide release, molecular modeling, and biological evaluation as anti-inflammatory agents.
    Kaur J; Bhardwaj A; Huang Z; Knaus EE
    ChemMedChem; 2012 Jan; 7(1):144-50. PubMed ID: 22095955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computer-aided discovery of anti-inflammatory thiazolidinones with dual cyclooxygenase/lipoxygenase inhibition.
    Geronikaki AA; Lagunin AA; Hadjipavlou-Litina DI; Eleftheriou PT; Filimonov DA; Poroikov VV; Alam I; Saxena AK
    J Med Chem; 2008 Mar; 51(6):1601-9. PubMed ID: 18311898
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A₂, cyclooxygenases, lipoxygenase and proinflammatory cytokines.
    Bukhari SN; Lauro G; Jantan I; Bifulco G; Amjad MW
    Bioorg Med Chem; 2014 Aug; 22(15):4151-61. PubMed ID: 24938495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production.
    Chen CS; Tan CM; Huang CH; Chang LC; Wang JP; Cheng FC; Chern JW
    Bioorg Med Chem; 2010 Jan; 18(2):597-604. PubMed ID: 20056549
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
    Tan CM; Chen GS; Chen CS; Chang PT; Chern JW
    Bioorg Med Chem; 2011 Nov; 19(21):6316-28. PubMed ID: 21958737
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of new orally effective analgesic and anti-inflammatory hybrid furoxanyl N-acylhydrazone derivatives.
    Hernández P; Cabrera M; Lavaggi ML; Celano L; Tiscornia I; Rodrigues da Costa T; Thomson L; Bollati-Fogolín M; Miranda AL; Lima LM; Barreiro EJ; González M; Cerecetto H
    Bioorg Med Chem; 2012 Mar; 20(6):2158-71. PubMed ID: 22356737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Abd El Razik HA; Badr MH; Atta AH; Mouneir SM; Abu-Serie MM
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
    Cusan C; Spalluto G; Prato M; Adams M; Bodensieck A; Bauer R; Tubaro A; Bernardi P; Da Ros T
    Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.