596 related articles for article (PubMed ID: 21109197)
1. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.
Shimazu T; Hirschey MD; Hua L; Dittenhafer-Reed KE; Schwer B; Lombard DB; Li Y; Bunkenborg J; Alt FW; Denu JM; Jacobson MP; Verdin E
Cell Metab; 2010 Dec; 12(6):654-61. PubMed ID: 21109197
[TBL] [Abstract][Full Text] [Related]
2. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Hirschey MD; Shimazu T; Goetzman E; Jing E; Schwer B; Lombard DB; Grueter CA; Harris C; Biddinger S; Ilkayeva OR; Stevens RD; Li Y; Saha AK; Ruderman NB; Bain JR; Newgard CB; Farese RV; Alt FW; Kahn CR; Verdin E
Nature; 2010 Mar; 464(7285):121-5. PubMed ID: 20203611
[TBL] [Abstract][Full Text] [Related]
3. SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.
Hirschey MD; Shimazu T; Capra JA; Pollard KS; Verdin E
Aging (Albany NY); 2011 Jun; 3(6):635-42. PubMed ID: 21701047
[TBL] [Abstract][Full Text] [Related]
4. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
Bharathi SS; Zhang Y; Mohsen AW; Uppala R; Balasubramani M; Schreiber E; Uechi G; Beck ME; Rardin MJ; Vockley J; Verdin E; Gibson BW; Hirschey MD; Goetzman ES
J Biol Chem; 2013 Nov; 288(47):33837-33847. PubMed ID: 24121500
[TBL] [Abstract][Full Text] [Related]
5. SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism.
Hirschey MD; Shimazu T; Huang JY; Schwer B; Verdin E
Cold Spring Harb Symp Quant Biol; 2011; 76():267-77. PubMed ID: 22114326
[TBL] [Abstract][Full Text] [Related]
6. Role of ketone signaling in the hepatic response to fasting.
Geisler CE; Ghimire S; Bogan RL; Renquist BJ
Am J Physiol Gastrointest Liver Physiol; 2019 May; 316(5):G623-G631. PubMed ID: 30767679
[TBL] [Abstract][Full Text] [Related]
7. Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3.
Kwon S; Seok S; Yau P; Li X; Kemper B; Kemper JK
J Biol Chem; 2017 Oct; 292(42):17312-17323. PubMed ID: 28808064
[TBL] [Abstract][Full Text] [Related]
8. Fasting-induced HMGCS2 expression in the kidney does not contribute to circulating ketones.
Venable AH; Lee LE; Feola K; Santoyo J; Broomfield T; Huen SC
Am J Physiol Renal Physiol; 2022 Apr; 322(4):F460-F467. PubMed ID: 35224990
[TBL] [Abstract][Full Text] [Related]
9. Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line.
Vilà-Brau A; De Sousa-Coelho AL; Mayordomo C; Haro D; Marrero PF
J Biol Chem; 2011 Jun; 286(23):20423-30. PubMed ID: 21502324
[TBL] [Abstract][Full Text] [Related]
10. SIRT3 mediates multi-tissue coupling for metabolic fuel switching.
Dittenhafer-Reed KE; Richards AL; Fan J; Smallegan MJ; Fotuhi Siahpirani A; Kemmerer ZA; Prolla TA; Roy S; Coon JJ; Denu JM
Cell Metab; 2015 Apr; 21(4):637-46. PubMed ID: 25863253
[TBL] [Abstract][Full Text] [Related]
11. Green Tea Polyphenols Ameliorate the Early Renal Damage Induced by a High-Fat Diet via Ketogenesis/SIRT3 Pathway.
Yi W; Xie X; Du M; Bu Y; Wu N; Yang H; Tian C; Xu F; Xiang S; Zhang P; Chen Z; Zuo X; Ying C
Oxid Med Cell Longev; 2017; 2017():9032792. PubMed ID: 28814987
[TBL] [Abstract][Full Text] [Related]
12. Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation.
Arima Y; Nakagawa Y; Takeo T; Ishida T; Yamada T; Hino S; Nakao M; Hanada S; Umemoto T; Suda T; Sakuma T; Yamamoto T; Watanabe T; Nagaoka K; Tanaka Y; Kawamura YK; Tonami K; Kurihara H; Sato Y; Yamagata K; Nakamura T; Araki S; Yamamoto E; Izumiya Y; Sakamoto K; Kaikita K; Matsushita K; Nishiyama K; Nakagata N; Tsujita K
Nat Metab; 2021 Feb; 3(2):196-210. PubMed ID: 33619377
[TBL] [Abstract][Full Text] [Related]
13. The mitochondrial NAD
Fu Z; Kim H; Morse PT; Lu MJ; Hüttemann M; Cambronne XA; Zhang K; Zhang R
Metabolism; 2022 Oct; 135():155275. PubMed ID: 35932995
[TBL] [Abstract][Full Text] [Related]
14. MicroRNA-195 Regulates Metabolism in Failing Myocardium Via Alterations in Sirtuin 3 Expression and Mitochondrial Protein Acetylation.
Zhang X; Ji R; Liao X; Castillero E; Kennel PJ; Brunjes DL; Franz M; Möbius-Winkler S; Drosatos K; George I; Chen EI; Colombo PC; Schulze PC
Circulation; 2018 May; 137(19):2052-2067. PubMed ID: 29330215
[TBL] [Abstract][Full Text] [Related]
15. Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation.
Xu Y; Ye X; Zhou Y; Cao X; Peng S; Peng Y; Zhang X; Sun Y; Jiang H; Huang W; Lian H; Yang J; Li J; Ye J
Front Med; 2023 Apr; 17(2):339-351. PubMed ID: 36602721
[TBL] [Abstract][Full Text] [Related]
16. Fasting hypoketotic coma in a child with deficiency of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase.
Thompson GN; Hsu BY; Pitt JJ; Treacy E; Stanley CA
N Engl J Med; 1997 Oct; 337(17):1203-7. PubMed ID: 9337379
[No Abstract] [Full Text] [Related]
17. SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
Novgorodov SA; Riley CL; Keffler JA; Yu J; Kindy MS; Macklin WB; Lombard DB; Gudz TI
J Biol Chem; 2016 Jan; 291(4):1957-1973. PubMed ID: 26620563
[TBL] [Abstract][Full Text] [Related]
18. Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity.
Finley LW; Haas W; Desquiret-Dumas V; Wallace DC; Procaccio V; Gygi SP; Haigis MC
PLoS One; 2011; 6(8):e23295. PubMed ID: 21858060
[TBL] [Abstract][Full Text] [Related]
19. Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism.
Helenius TO; Misiorek JO; Nyström JH; Fortelius LE; Habtezion A; Liao J; Asghar MN; Zhang H; Azhar S; Omary MB; Toivola DM
Mol Biol Cell; 2015 Jun; 26(12):2298-310. PubMed ID: 25904331
[TBL] [Abstract][Full Text] [Related]
20. SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress.
Vassilopoulos A; Pennington JD; Andresson T; Rees DM; Bosley AD; Fearnley IM; Ham A; Flynn CR; Hill S; Rose KL; Kim HS; Deng CX; Walker JE; Gius D
Antioxid Redox Signal; 2014 Aug; 21(4):551-64. PubMed ID: 24252090
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]