These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 21109950)

  • 1. Two small molecule compounds, LLL12 and FLLL32, exhibit potent inhibitory activity on STAT3 in human rhabdomyosarcoma cells.
    Wei CC; Ball S; Lin L; Liu A; Fuchs JR; Li PK; Li C; Lin J
    Int J Oncol; 2011 Jan; 38(1):279-85. PubMed ID: 21109950
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.
    Onimoe GI; Liu A; Lin L; Wei CC; Schwartz EB; Bhasin D; Li C; Fuchs JR; Li PK; Houghton P; Termuhlen A; Gross T; Lin J
    Invest New Drugs; 2012 Jun; 30(3):916-26. PubMed ID: 21340507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
    Lin L; Hutzen B; Li PK; Ball S; Zuo M; DeAngelis S; Foust E; Sobo M; Friedman L; Bhasin D; Cen L; Li C; Lin J
    Neoplasia; 2010 Jan; 12(1):39-50. PubMed ID: 20072652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells.
    Liu A; Liu Y; Xu Z; Yu W; Wang H; Li C; Lin J
    Cancer Sci; 2011 Jul; 102(7):1381-7. PubMed ID: 21435102
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells.
    Reed S; Li H; Li C; Lin J
    Biochem Biophys Res Commun; 2011 Apr; 407(3):450-5. PubMed ID: 21397587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer cells.
    Lin L; Jou D; Wang Y; Ma H; Liu T; Fuchs J; Li PK; Lü J; Li C; Lin J
    Int J Oncol; 2016 Dec; 49(6):2265-2274. PubMed ID: 27748818
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.
    Lin L; Benson DM; DeAngelis S; Bakan CE; Li PK; Li C; Lin J
    Int J Cancer; 2012 Mar; 130(6):1459-69. PubMed ID: 21520044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells.
    Lin L; Hutzen B; Zuo M; Ball S; Deangelis S; Foust E; Pandit B; Ihnat MA; Shenoy SS; Kulp S; Li PK; Li C; Fuchs J; Lin J
    Cancer Res; 2010 Mar; 70(6):2445-54. PubMed ID: 20215512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
    Duan Z; Bradner J; Greenberg E; Mazitschek R; Foster R; Mahoney J; Seiden MV
    Mol Pharmacol; 2007 Nov; 72(5):1137-45. PubMed ID: 17675586
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.
    Lin L; Deangelis S; Foust E; Fuchs J; Li C; Li PK; Schwartz EB; Lesinski GB; Benson D; Lü J; Hoyt D; Lin J
    Mol Cancer; 2010 Aug; 9():217. PubMed ID: 20712901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo.
    Iwamaru A; Szymanski S; Iwado E; Aoki H; Yokoyama T; Fokt I; Hess K; Conrad C; Madden T; Sawaya R; Kondo S; Priebe W; Kondo Y
    Oncogene; 2007 Apr; 26(17):2435-44. PubMed ID: 17043651
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.
    Bill MA; Nicholas C; Mace TA; Etter JP; Li C; Schwartz EB; Fuchs JR; Young GS; Lin L; Lin J; He L; Phelps M; Li PK; Lesinski GB
    PLoS One; 2012; 7(8):e40724. PubMed ID: 22899991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.
    Ball S; Li C; Li PK; Lin J
    PLoS One; 2011 Apr; 6(4):e18820. PubMed ID: 21526200
    [TBL] [Abstract][Full Text] [Related]  

  • 14. STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH⁺/CD133⁺ stem cell-like human colon cancer cells.
    Lin L; Fuchs J; Li C; Olson V; Bekaii-Saab T; Lin J
    Biochem Biophys Res Commun; 2011 Dec; 416(3-4):246-51. PubMed ID: 22074823
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis.
    Kusaba M; Nakao K; Goto T; Nishimura D; Kawashimo H; Shibata H; Motoyoshi Y; Taura N; Ichikawa T; Hamasaki K; Eguchi K
    J Hepatol; 2007 Oct; 47(4):546-55. PubMed ID: 17602782
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A small molecule STAT3 inhibitor, LLL12, enhances cisplatin‑ and paclitaxel‑mediated inhibition of cell growth and migration in human ovarian cancer cells.
    Zhang R; Chen X; Fu S; Xu L; Lin J
    Oncol Rep; 2020 Sep; 44(3):1224-1232. PubMed ID: 32705214
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity.
    Bill MA; Fuchs JR; Li C; Yui J; Bakan C; Benson DM; Schwartz EB; Abdelhamid D; Lin J; Hoyt DG; Fossey SL; Young GS; Carson WE; Li PK; Lesinski GB
    Mol Cancer; 2010 Jun; 9():165. PubMed ID: 20576164
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Contribution of STAT3 to the activation of survivin by GM-CSF in CD34+ cell lines.
    Gu L; Chiang KY; Zhu N; Findley HW; Zhou M
    Exp Hematol; 2007 Jun; 35(6):957-66. PubMed ID: 17533050
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation.
    Ashizawa T; Miyata H; Ishii H; Oshita C; Matsuno K; Masuda Y; Furuya T; Okawara T; Otsuka M; Ogo N; Asai A; Akiyama Y
    Int J Oncol; 2011 May; 38(5):1245-52. PubMed ID: 21369699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy.
    Zuo M; Li C; Lin J; Javle M
    Oncotarget; 2015 May; 6(13):10940-9. PubMed ID: 25883212
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.