728 related articles for article (PubMed ID: 21111054)
1. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
[TBL] [Abstract][Full Text] [Related]
2. An 'all-inclusive' 96-well cytochrome P450 induction method: measuring enzyme activity, mRNA levels, protein levels, and cytotoxicity from one well using cryopreserved human hepatocytes.
Halladay JS; Wong S; Khojasteh SC; Grepper S
J Pharmacol Toxicol Methods; 2012; 66(3):270-5. PubMed ID: 22809809
[TBL] [Abstract][Full Text] [Related]
3. Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies.
Kenny JR; Chen L; McGinnity DF; Grime K; Shakesheff KM; Thomson B; Riley R
Xenobiotica; 2008 Dec; 38(12):1500-17. PubMed ID: 18989830
[TBL] [Abstract][Full Text] [Related]
4. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
5. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
[TBL] [Abstract][Full Text] [Related]
6. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
Li L; Stanton JD; Tolson AH; Luo Y; Wang H
Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
[TBL] [Abstract][Full Text] [Related]
7. A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin.
Zhang JG; Ho T; Callendrello AL; Crespi CL; Stresser DM
Drug Metab Lett; 2010 Dec; 4(4):185-94. PubMed ID: 20583967
[TBL] [Abstract][Full Text] [Related]
8. The role of constitutive androstane receptor in oxazaphosphorine-mediated induction of drug-metabolizing enzymes in human hepatocytes.
Wang D; Li L; Fuhrman J; Ferguson S; Wang H
Pharm Res; 2011 Aug; 28(8):2034-44. PubMed ID: 21487929
[TBL] [Abstract][Full Text] [Related]
9. Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.
Saussele T; Burk O; Blievernicht JK; Klein K; Nussler A; Nussler N; Hengstler JG; Eichelbaum M; Schwab M; Zanger UM
Clin Pharmacol Ther; 2007 Sep; 82(3):265-74. PubMed ID: 17344806
[TBL] [Abstract][Full Text] [Related]
10. Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells.
Ogasawara A; Kato N; Torimoto N; Aohara F; Ohashi R; Yamada Y; Taniguchi H
Drug Metab Lett; 2018; 12(1):14-23. PubMed ID: 29357810
[TBL] [Abstract][Full Text] [Related]
11. Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition.
Duniec-Dmuchowski Z; Fang HL; Strom SC; Ellis E; Runge-Morris M; Kocarek TA
Drug Metab Dispos; 2009 Apr; 37(4):900-8. PubMed ID: 19158313
[TBL] [Abstract][Full Text] [Related]
12. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
13. Mechanism of autoinduction of methadone N-demethylation in human hepatocytes.
Campbell SD; Crafford A; Williamson BL; Kharasch ED
Anesth Analg; 2013 Jul; 117(1):52-60. PubMed ID: 23733841
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes.
Xing J; Kirby BJ; Whittington D; Wan Y; Goodlett DR
Drug Metab Dispos; 2012 Sep; 40(9):1757-64. PubMed ID: 22679214
[TBL] [Abstract][Full Text] [Related]
15. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
[TBL] [Abstract][Full Text] [Related]
16. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
17. Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system.
Pimkaew P; Küblbeck J; Petsalo A; Jukka J; Suksamrarn A; Juvonen R; Auriola S; Piyachaturawat P; Honkakoski P
Toxicol In Vitro; 2013 Sep; 27(6):2005-12. PubMed ID: 23850985
[TBL] [Abstract][Full Text] [Related]
18. The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes.
Ayed-Boussema I; Pascussi JM; Rjiba K; Maurel P; Bacha H; Hassen W
Drug Chem Toxicol; 2012 Jul; 35(3):241-50. PubMed ID: 21939362
[TBL] [Abstract][Full Text] [Related]
19. Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor.
Kohalmy K; Tamási V; Kóbori L; Sárváry E; Pascussi JM; Porrogi P; Rozman D; Prough RA; Meyer UA; Monostory K
Drug Metab Dispos; 2007 Sep; 35(9):1495-501. PubMed ID: 17591676
[TBL] [Abstract][Full Text] [Related]
20. Induction of CYP2B6 and CYP3A4 expression by 1-aminobenzotriazole (ABT) in human hepatocytes.
Yang K; Koh KH; Jeong H
Drug Metab Lett; 2010 Aug; 4(3):129-33. PubMed ID: 20642445
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]