BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 2111164)

  • 1. Kinetic and conformational effects of lysine substitutions for arginines 35 and 87 in the active site of staphylococcal nuclease.
    Pourmotabbed T; Dell'Acqua M; Gerlt JA; Stanczyk SM; Bolton PH
    Biochemistry; 1990 Apr; 29(15):3677-83. PubMed ID: 2111164
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of residues involved in a conformational change accompanying substitutions for glutamate-43 in staphylococcal nuclease.
    Wilde JA; Bolton PH; Dell'Acqua M; Hibler DW; Pourmotabbed T; Gerlt JA
    Biochemistry; 1988 May; 27(11):4127-32. PubMed ID: 2843224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of conformational features of staphylococcal nuclease in ternary complexes with pdTp, pdGp, and nitrophenyl-pdTp.
    Stanczyk SM; Bolton PH
    Biochemistry; 1992 Jul; 31(28):6396-401. PubMed ID: 1633152
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletion of the omega-loop in the active site of staphylococcal nuclease. 1. Effect on catalysis and stability.
    Poole LB; Loveys DA; Hale SP; Gerlt JA; Stanczyk SM; Bolton PH
    Biochemistry; 1991 Apr; 30(15):3621-7. PubMed ID: 2015219
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Site-directed mutants of staphylococcal nuclease. Detection and localization by 1H NMR spectroscopy of conformational changes accompanying substitutions for glutamic acid-43.
    Hibler DW; Stolowich NJ; Reynolds MA; Gerlt JA; Wilde JA; Bolton PH
    Biochemistry; 1987 Sep; 26(19):6278-86. PubMed ID: 2891375
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interactions of the acid and base catalysts on staphylococcal nuclease as studied in a double mutant.
    Weber DJ; Meeker AK; Mildvan AS
    Biochemistry; 1991 Jun; 30(25):6103-14. PubMed ID: 1676297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NMR docking of the competitive inhibitor thymidine 3',5'-diphosphate into the X-ray structure of staphylococcal nuclease.
    Weber DJ; Serpersu EH; Gittis AG; Lattman EE; Mildvan AS
    Proteins; 1993 Sep; 17(1):20-35. PubMed ID: 8234242
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion of the omega-loop in the active site of staphylococcal nuclease. 2. Effects on protein structure and dynamics.
    Baldisseri DM; Torchia DA; Poole LB; Gerlt JA
    Biochemistry; 1991 Apr; 30(15):3628-33. PubMed ID: 2015220
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase.
    Harris TK; Czerwinski RM; Johnson WH; Legler PM; Abeygunawardana C; Massiah MA; Stivers JT; Whitman CP; Mildvan AS
    Biochemistry; 1999 Sep; 38(38):12343-57. PubMed ID: 10493802
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effects of amino acid replacements of glycine 20 on conformational stability and catalysis of staphylococcal nuclease.
    Feng Y; Huang S; Zhang W; Zeng Z; Zou X; Zhong L; Peng J; Jing G
    Biochimie; 2004 Dec; 86(12):893-901. PubMed ID: 15667939
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational features of a truncated staphylococcal nuclease R (SNR135) and their implications for catalysis.
    Zhou B; Jing GZ
    Arch Biochem Biophys; 1998 Dec; 360(1):33-40. PubMed ID: 9826426
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of adenylate kinase. The "essential lysine" helps to orient the phosphates and the active site residues to proper conformations.
    Byeon L; Shi Z; Tsai MD
    Biochemistry; 1995 Mar; 34(10):3172-82. PubMed ID: 7880812
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinetic and magnetic resonance studies of active-site mutants of staphylococcal nuclease: factors contributing to catalysis.
    Serpersu EH; Shortle D; Mildvan AS
    Biochemistry; 1987 Mar; 26(5):1289-300. PubMed ID: 3567171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutational tests of the NMR-docked structure of the staphylococcal nuclease-metal-3',5'-pdTp complex.
    Chuang WJ; Weber DJ; Gittis AG; Mildvan AS
    Proteins; 1993 Sep; 17(1):36-48. PubMed ID: 8234243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase.
    Harris TK; Wu G; Massiah MA; Mildvan AS
    Biochemistry; 2000 Feb; 39(7):1655-74. PubMed ID: 10677214
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Active site mutant Glu-43----Asp in staphylococcal nuclease displays nonlocal structural changes.
    Loll PJ; Lattman EE
    Biochemistry; 1990 Jul; 29(29):6866-73. PubMed ID: 2397218
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations can cause large changes in the conformation of a denatured protein.
    Flanagan JM; Kataoka M; Fujisawa T; Engelman DM
    Biochemistry; 1993 Oct; 32(39):10359-70. PubMed ID: 8399179
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
    Libson AM; Gittis AG; Lattman EE
    Biochemistry; 1994 Jul; 33(26):8007-16. PubMed ID: 8025105
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetic and magnetic resonance studies of effects of genetic substitution of a Ca2+-liganding amino acid in staphylococcal nuclease.
    Serpersu EH; Shortle D; Mildvan AS
    Biochemistry; 1986 Jan; 25(1):68-77. PubMed ID: 3513826
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution studies of staphylococcal nuclease H124L. 2. 1H, 13C, and 15N chemical shift assignments for the unligated enzyme and analysis of chemical shift changes that accompany formation of the nuclease-thymidine 3',5'-bisphosphate-calcium ternary complex.
    Wang JF; Hinck AP; Loh SN; LeMaster DM; Markley JL
    Biochemistry; 1992 Jan; 31(3):921-36. PubMed ID: 1731949
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.