BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 21113147)

  • 1. Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways.
    Zhang L; Lopez H; George NM; Liu X; Pang X; Luo X
    Cell Death Differ; 2011 May; 18(5):864-73. PubMed ID: 21113147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H; Wolf J; Schafer B; Moldoveanu T; Chipuk JE; Kuwana T
    J Biol Chem; 2011 Jan; 286(1):491-501. PubMed ID: 21041309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional linkage between NOXA and Bim in mitochondrial apoptotic events.
    Han J; Goldstein LA; Hou W; Rabinowich H
    J Biol Chem; 2007 Jun; 282(22):16223-31. PubMed ID: 17374615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S; Borrow J; Zhang XD; Hersey P
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN; Fletcher JI; Kaufmann T; van Delft MF; Chen L; Czabotar PE; Ierino H; Lee EF; Fairlie WD; Bouillet P; Strasser A; Kluck RM; Adams JM; Huang DC
    Science; 2007 Feb; 315(5813):856-9. PubMed ID: 17289999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.
    Clohessy JG; Zhuang J; de Boer J; Gil-Gómez G; Brady HJ
    J Biol Chem; 2006 Mar; 281(9):5750-9. PubMed ID: 16380381
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and Noxa.
    Inoue S; Riley J; Gant TW; Dyer MJ; Cohen GM
    Leukemia; 2007 Aug; 21(8):1773-82. PubMed ID: 17525724
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.
    Meng XW; Lee SH; Dai H; Loegering D; Yu C; Flatten K; Schneider P; Dai NT; Kumar SK; Smith BD; Karp JE; Adjei AA; Kaufmann SH
    J Biol Chem; 2007 Oct; 282(41):29831-46. PubMed ID: 17698840
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
    Chen S; Dai Y; Pei XY; Grant S
    Mol Cell Biol; 2009 Dec; 29(23):6149-69. PubMed ID: 19805519
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis.
    Han J; Goldstein LA; Gastman BR; Rabinowich H
    J Biol Chem; 2006 Apr; 281(15):10153-63. PubMed ID: 16478725
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
    Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P; Wuillème-Toumi S; Ménoret E; Trichet V; Robillard N; Philippe M; Bataille R; Amiot M
    Cancer Res; 2007 Jun; 67(11):5418-24. PubMed ID: 17545623
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
    Huang S; Sinicrope FA
    Cancer Res; 2008 Apr; 68(8):2944-51. PubMed ID: 18413764
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.
    Werneburg NW; Guicciardi ME; Bronk SF; Kaufmann SH; Gores GJ
    J Biol Chem; 2007 Sep; 282(39):28960-28970. PubMed ID: 17686764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K; O'Neill KL; Li J; Zhou W; Han N; Pang X; Wu W; Struble L; Borgstahl G; Liu Z; Zhang L; Luo X
    Cell Res; 2019 Nov; 29(11):942-952. PubMed ID: 31551537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.
    Nakajima W; Tanaka N
    J Nippon Med Sch; 2007 Apr; 74(2):148-57. PubMed ID: 17507791
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax.
    Jiang CC; Wroblewski D; Yang F; Hersey P; Zhang XD
    Neoplasia; 2009 Sep; 11(9):945-55. PubMed ID: 19724688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S; Okumura K; Sinicrope FA
    Clin Cancer Res; 2009 Jan; 15(1):150-9. PubMed ID: 19118042
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.