250 related articles for article (PubMed ID: 21113787)
1. PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma.
Rodriguez EF; Scheithauer BW; Giannini C; Rynearson A; Cen L; Hoesley B; Gilmer-Flynn H; Sarkaria JN; Jenkins S; Long J; Rodriguez FJ
Acta Neuropathol; 2011 Mar; 121(3):407-20. PubMed ID: 21113787
[TBL] [Abstract][Full Text] [Related]
2. PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor.
Perrone F; Da Riva L; Orsenigo M; Losa M; Jocollè G; Millefanti C; Pastore E; Gronchi A; Pierotti MA; Pilotti S
Neuro Oncol; 2009 Dec; 11(6):725-36. PubMed ID: 19246520
[TBL] [Abstract][Full Text] [Related]
3. Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Reinhardt A; Stichel D; Schrimpf D; Sahm F; Korshunov A; Reuss DE; Koelsche C; Huang K; Wefers AK; Hovestadt V; Sill M; Gramatzki D; Felsberg J; Reifenberger G; Koch A; Thomale UW; Becker A; Hans VH; Prinz M; Staszewski O; Acker T; Dohmen H; Hartmann C; Mueller W; Tuffaha MSA; Paulus W; Heß K; Brokinkel B; Schittenhelm J; Monoranu CM; Kessler AF; Loehr M; Buslei R; Deckert M; Mawrin C; Kohlhof P; Hewer E; Olar A; Rodriguez FJ; Giannini C; NageswaraRao AA; Tabori U; Nunes NM; Weller M; Pohl U; Jaunmuktane Z; Brandner S; Unterberg A; Hänggi D; Platten M; Pfister SM; Wick W; Herold-Mende C; Jones DTW; von Deimling A; Capper D
Acta Neuropathol; 2018 Aug; 136(2):273-291. PubMed ID: 29564591
[TBL] [Abstract][Full Text] [Related]
4. Analysis of PIK3CA and B-RAF gene mutations in human astrocytomas: association with activation of ERK and AKT.
El-Habr EA; Tsiorva P; Theodorou M; Levidou G; Korkolopoulou P; Vretakos G; Petraki L; Michalopoulos NV; Patsouris E; Saetta AA
Clin Neuropathol; 2010; 29(4):239-45. PubMed ID: 20569675
[TBL] [Abstract][Full Text] [Related]
5. ATRX protein loss and deregulation of PI3K/AKT pathway is frequent in pilocytic astrocytoma with anaplastic features.
Olar A; Tran D; Mehta VP; Reinhardt A; Manekia JH; Garnovskaya M; Ellezam B; Luthra R; Sulman EP; Mohila CA; Campbell GA; Powell SZ; Fuller GN; Aldape KD; Adesina AM
Clin Neuropathol; 2019; 38(2):59-73. PubMed ID: 30499772
[TBL] [Abstract][Full Text] [Related]
6. Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?
Hlobilkova A; Ehrmann J; Sedlakova E; Krejci V; Knizetova P; Fiuraskova M; Kala M; Kalita O; Kolar Z
Neoplasma; 2007; 54(4):334-41. PubMed ID: 17822324
[TBL] [Abstract][Full Text] [Related]
7. Genetic alterations related to BRAF-FGFR genes and dysregulated MAPK/ERK/mTOR signaling in adult pilocytic astrocytoma.
Pathak P; Kumar A; Jha P; Purkait S; Faruq M; Suri A; Suri V; Sharma MC; Sarkar C
Brain Pathol; 2017 Sep; 27(5):580-589. PubMed ID: 27608415
[TBL] [Abstract][Full Text] [Related]
8. BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper.
Rodriguez FJ; Ligon AH; Horkayne-Szakaly I; Rushing EJ; Ligon KL; Vena N; Garcia DI; Cameron JD; Eberhart CG
J Neuropathol Exp Neurol; 2012 Sep; 71(9):789-94. PubMed ID: 22892521
[TBL] [Abstract][Full Text] [Related]
9. Targeting RAS-MAPK-ERK and PI3K-AKT-mTOR signal transduction pathways to chemosensitize anaplastic thyroid carcinoma.
Milosevic Z; Pesic M; Stankovic T; Dinic J; Milovanovic Z; Stojsic J; Dzodic R; Tanic N; Bankovic J
Transl Res; 2014 Nov; 164(5):411-23. PubMed ID: 25016932
[TBL] [Abstract][Full Text] [Related]
10. Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas.
Jacob K; Quang-Khuong DA; Jones DT; Witt H; Lambert S; Albrecht S; Witt O; Vezina C; Shirinian M; Faury D; Garami M; Hauser P; Klekner A; Bognar L; Farmer JP; Montes JL; Atkinson J; Hawkins C; Korshunov A; Collins VP; Pfister SM; Tabori U; Jabado N
Clin Cancer Res; 2011 Jul; 17(14):4650-60. PubMed ID: 21610151
[TBL] [Abstract][Full Text] [Related]
11. Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies.
Gürsel DB; Connell-Albert YS; Tuskan RG; Anastassiadis T; Walrath JC; Hawes JJ; Amlin-Van Schaick JC; Reilly KM
Neuro Oncol; 2011 Jun; 13(6):610-21. PubMed ID: 21636709
[TBL] [Abstract][Full Text] [Related]
12. Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers.
Liu Z; Hou P; Ji M; Guan H; Studeman K; Jensen K; Vasko V; El-Naggar AK; Xing M
J Clin Endocrinol Metab; 2008 Aug; 93(8):3106-16. PubMed ID: 18492751
[TBL] [Abstract][Full Text] [Related]
13. Adult with cerebellar anaplastic pilocytic astrocytoma associated with BRAF V600E mutation and p16 loss.
Yeo YH; Byrne NP; Counelis GJ; Perry A
Clin Neuropathol; 2013; 32(3):159-64. PubMed ID: 23196000
[TBL] [Abstract][Full Text] [Related]
14. Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia.
Rodriguez FJ; Brosnan-Cashman JA; Allen SJ; Vizcaino MA; Giannini C; Camelo-Piragua S; Webb M; Matsushita M; Wadhwani N; Tabbarah A; Hamideh D; Jiang L; Chen L; Arvanitis LD; Alnajar HH; Barber JR; Rodríguez-Velasco A; Orr B; Heaphy CM
Brain Pathol; 2019 Jan; 29(1):126-140. PubMed ID: 30192422
[TBL] [Abstract][Full Text] [Related]
15. Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas--Same Entity or First Cousins?
Alexandrescu S; Korshunov A; Lai SH; Dabiri S; Patil S; Li R; Shih CS; Bonnin JM; Baker JA; Du E; Scharnhorst DW; Samuel D; Ellison DW; Perry A
Brain Pathol; 2016 Mar; 26(2):215-23. PubMed ID: 26238627
[TBL] [Abstract][Full Text] [Related]
16. Expression of pERK and pAKT in human astrocytomas: correlation with IDH1-R132H presence, vascular endothelial growth factor, microvascular characteristics and clinical outcome.
Saetta AA; Levidou G; El-Habr EA; Panayotidis I; Samaras V; Thymara I; Sakellariou S; Boviatsis E; Patsouris E; Korkolopoulou P
Virchows Arch; 2011 Jun; 458(6):749-59. PubMed ID: 21494763
[TBL] [Abstract][Full Text] [Related]
17. BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern.
Ida CM; Lambert SR; Rodriguez FJ; Voss JS; Mc Cann BE; Seys AR; Halling KC; Collins VP; Giannini C
J Neuropathol Exp Neurol; 2012 Jul; 71(7):631-9. PubMed ID: 22710963
[TBL] [Abstract][Full Text] [Related]
18. Pilocytic astrocytomas of the optic nerve and their relation to pilocytic astrocytomas elsewhere in the central nervous system.
Reis GF; Bloomer MM; Perry A; Phillips JJ; Grenert JP; Karnezis AN; Tihan T
Mod Pathol; 2013 Oct; 26(10):1279-87. PubMed ID: 23702730
[TBL] [Abstract][Full Text] [Related]
19. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
[TBL] [Abstract][Full Text] [Related]
20. V600E BRAF mutation in pilocytic astrocytoma is associated with a more diffuse growth pattern but does not confer a more aggressive clinical behavior.
Bannykh SI; Mirocha J; Nuno M; Lopategui J; Kandala G
Clin Neuropathol; 2014; 33(6):388-98. PubMed ID: 25066317
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
