These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2127 related articles for article (PubMed ID: 21115425)
1. Evolving strategies for overcoming resistance to HER2-directed therapy: targeting the PI3K/Akt/mTOR pathway. Nahta R; O'Regan RM Clin Breast Cancer; 2010 Nov; 10 Suppl 3():S72-8. PubMed ID: 21115425 [TBL] [Abstract][Full Text] [Related]
2. Potential of overcoming resistance to HER2-targeted therapies through the PI3K/Akt/mTOR pathway. Wilks ST Breast; 2015 Oct; 24(5):548-55. PubMed ID: 26187798 [TBL] [Abstract][Full Text] [Related]
3. Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers? Zardavas D; Fumagalli D; Loi S Curr Opin Oncol; 2012 Nov; 24(6):623-34. PubMed ID: 22960556 [TBL] [Abstract][Full Text] [Related]
4. Targeting endocrine resistance: is there a role for mTOR inhibition? Sheri A; Martin LA; Johnston S Clin Breast Cancer; 2010 Nov; 10 Suppl 3():S79-85. PubMed ID: 21115426 [TBL] [Abstract][Full Text] [Related]
5. Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer. Nahta R; Yu D; Hung MC; Hortobagyi GN; Esteva FJ Nat Clin Pract Oncol; 2006 May; 3(5):269-80. PubMed ID: 16683005 [TBL] [Abstract][Full Text] [Related]
6. Everolimus: targeted therapy on the horizon for the treatment of breast cancer. Barnett CM Pharmacotherapy; 2012 Apr; 32(4):383-96. PubMed ID: 22461124 [TBL] [Abstract][Full Text] [Related]
7. Everolimus and its role in hormone-resistant and trastuzumab-resistant metastatic breast cancer. Keck S; Glencer AC; Rugo HS Future Oncol; 2012 Nov; 8(11):1383-96. PubMed ID: 23148612 [TBL] [Abstract][Full Text] [Related]
8. Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor. Tseng PH; Wang YC; Weng SC; Weng JR; Chen CS; Brueggemeier RW; Shapiro CL; Chen CY; Dunn SE; Pollak M; Chen CS Mol Pharmacol; 2006 Nov; 70(5):1534-41. PubMed ID: 16887935 [TBL] [Abstract][Full Text] [Related]
9. Overcoming resistance and restoring sensitivity to HER2-targeted therapies in breast cancer. Mohd Sharial MSN; Crown J; Hennessy BT Ann Oncol; 2012 Dec; 23(12):3007-3016. PubMed ID: 22865781 [TBL] [Abstract][Full Text] [Related]
10. Everolimus: a new hope for patients with breast cancer. Sendur MA; Zengin N; Aksoy S; Altundag K Curr Med Res Opin; 2014 Jan; 30(1):75-87. PubMed ID: 24050600 [TBL] [Abstract][Full Text] [Related]
11. The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells. Brünner-Kubath C; Shabbir W; Saferding V; Wagner R; Singer CF; Valent P; Berger W; Marian B; Zielinski CC; Grusch M; Grunt TW Breast Cancer Res Treat; 2011 Sep; 129(2):387-400. PubMed ID: 21046231 [TBL] [Abstract][Full Text] [Related]
12. Progression and treatment of HER2-positive breast cancer. Davoli A; Hocevar BA; Brown TL Cancer Chemother Pharmacol; 2010 Mar; 65(4):611-23. PubMed ID: 20087739 [TBL] [Abstract][Full Text] [Related]
13. Evolving nonendocrine therapeutic options for metastatic breast cancer: how adjuvant chemotherapy influences treatment. Conte P; Guarneri V; Bengala C Clin Breast Cancer; 2007 Dec; 7(11):841-9. PubMed ID: 18269773 [TBL] [Abstract][Full Text] [Related]
14. A systematic review of dual targeting in HER2-positive breast cancer. Kümler I; Tuxen MK; Nielsen DL Cancer Treat Rev; 2014 Mar; 40(2):259-70. PubMed ID: 24080156 [TBL] [Abstract][Full Text] [Related]
15. MUC1* is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells. Fessler SP; Wotkowicz MT; Mahanta SK; Bamdad C Breast Cancer Res Treat; 2009 Nov; 118(1):113-24. PubMed ID: 19415485 [TBL] [Abstract][Full Text] [Related]
16. Blockade of the HER family of receptors in the treatment of HER2-positive metastatic breast cancer. Sachdev JC; Jahanzeb M Clin Breast Cancer; 2012 Feb; 12(1):19-29. PubMed ID: 21903480 [TBL] [Abstract][Full Text] [Related]
17. Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer. Fumarola C; Bonelli MA; Petronini PG; Alfieri RR Biochem Pharmacol; 2014 Aug; 90(3):197-207. PubMed ID: 24863259 [TBL] [Abstract][Full Text] [Related]
18. HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib. Valabrega G; Capellero S; Cavalloni G; Zaccarello G; Petrelli A; Migliardi G; Milani A; Peraldo-Neia C; Gammaitoni L; Sapino A; Pecchioni C; Moggio A; Giordano S; Aglietta M; Montemurro F Breast Cancer Res Treat; 2011 Nov; 130(1):29-40. PubMed ID: 21153051 [TBL] [Abstract][Full Text] [Related]
19. Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells. Vazquez-Martin A; Colomer R; Brunet J; Menendez JA Int J Oncol; 2007 Oct; 31(4):769-76. PubMed ID: 17786307 [TBL] [Abstract][Full Text] [Related]
20. Antibodies as molecular target-based therapy: trastuzumab. Tokuda Y Int J Clin Oncol; 2003 Aug; 8(4):224-9. PubMed ID: 12955577 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]