297 related articles for article (PubMed ID: 21118110)
1. Presenilins: how much more than γ-secretase?!
Coen K; Annaert W
Biochem Soc Trans; 2010 Dec; 38(6):1474-8. PubMed ID: 21118110
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
[TBL] [Abstract][Full Text] [Related]
3. Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.
Supnet C; Bezprozvanny I
Sci China Life Sci; 2011 Aug; 54(8):744-51. PubMed ID: 21786197
[TBL] [Abstract][Full Text] [Related]
4. Presenilin mouse and zebrafish models for dementia: focus on neurogenesis.
van Tijn P; Kamphuis W; Marlatt MW; Hol EM; Lucassen PJ
Prog Neurobiol; 2011 Feb; 93(2):149-64. PubMed ID: 21056616
[TBL] [Abstract][Full Text] [Related]
5. Alzheimer's disease sends the wrong signals--a perspective.
Neve RL
Amyloid; 2008 Mar; 15(1):1-4. PubMed ID: 18266116
[TBL] [Abstract][Full Text] [Related]
6. γ-Secretase component presenilin is important for microglia β-amyloid clearance.
Farfara D; Trudler D; Segev-Amzaleg N; Galron R; Stein R; Frenkel D
Ann Neurol; 2011 Jan; 69(1):170-80. PubMed ID: 21280087
[TBL] [Abstract][Full Text] [Related]
7. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
Zhou S; Zhou H; Walian PJ; Jap BK
Proc Natl Acad Sci U S A; 2005 May; 102(21):7499-504. PubMed ID: 15890777
[TBL] [Abstract][Full Text] [Related]
8. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
Brijbassi S; Amtul Z; Newbigging S; Westaway D; St George-Hyslop P; Rozmahel RF
Neurobiol Dis; 2007 Feb; 25(2):291-6. PubMed ID: 17071095
[TBL] [Abstract][Full Text] [Related]
9. Presenilin diversifies its portfolio.
Parks AL; Curtis D
Trends Genet; 2007 Mar; 23(3):140-50. PubMed ID: 17280736
[TBL] [Abstract][Full Text] [Related]
10. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
Shirotani K; Tomioka M; Kremmer E; Haass C; Steiner H
Neurobiol Dis; 2007 Jul; 27(1):102-7. PubMed ID: 17560791
[TBL] [Abstract][Full Text] [Related]
11. Dilysine retrieval signal-containing p24 proteins collaborate in inhibiting γ-cleavage of amyloid precursor protein.
Hasegawa H; Liu L; Nishimura M
J Neurochem; 2010 Nov; 115(3):771-81. PubMed ID: 20807314
[TBL] [Abstract][Full Text] [Related]
12. Beyond γ-secretase activity: The multifunctional nature of presenilins in cell signalling pathways.
Duggan SP; McCarthy JV
Cell Signal; 2016 Jan; 28(1):1-11. PubMed ID: 26498858
[TBL] [Abstract][Full Text] [Related]
13. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
[TBL] [Abstract][Full Text] [Related]
14. The Alzheimer's disease-associated gamma-secretase complex: functional domains in the presenilin 1 protein.
Laudon H; Winblad B; Näslund J
Physiol Behav; 2007 Sep; 92(1-2):115-20. PubMed ID: 17588625
[TBL] [Abstract][Full Text] [Related]
15. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
[TBL] [Abstract][Full Text] [Related]
16. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
Wolfe MS; Xia W; Ostaszewski BL; Diehl TS; Kimberly WT; Selkoe DJ
Nature; 1999 Apr; 398(6727):513-7. PubMed ID: 10206644
[TBL] [Abstract][Full Text] [Related]
17. Cloning, sequencing and expression in the dog of the main amyloid precursor protein isoforms and some of the enzymes related with their processing.
Sarasa L; Gallego C; Monleón I; Olvera A; Canudas J; Montañés M; Pesini P; Sarasa M
Neuroscience; 2010 Dec; 171(4):1091-101. PubMed ID: 20875843
[TBL] [Abstract][Full Text] [Related]
18. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
[TBL] [Abstract][Full Text] [Related]
19. A family of membrane proteins associated with presenilin expression and gamma-secretase function.
Araki W; Takahashi-Sasaki N; Chui DH; Saito S; Takeda K; Shirotani K; Takahashi K; Murayama KS; Kametani F; Shiraishi H; Komano H; Tabira T
FASEB J; 2008 Mar; 22(3):819-27. PubMed ID: 17928364
[TBL] [Abstract][Full Text] [Related]
20. Alzheimer's disease and Notch signaling.
Woo HN; Park JS; Gwon AR; Arumugam TV; Jo DG
Biochem Biophys Res Commun; 2009 Dec; 390(4):1093-7. PubMed ID: 19853579
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
