272 related articles for article (PubMed ID: 21118977)
1. Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer.
Rosenblatt AE; Garcia MI; Lyons L; Xie Y; Maiorino C; Désiré L; Slingerland J; Burnstein KL
Endocr Relat Cancer; 2011 Apr; 18(2):207-19. PubMed ID: 21118977
[TBL] [Abstract][Full Text] [Related]
2. Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α.
Barone I; Brusco L; Gu G; Selever J; Beyer A; Covington KR; Tsimelzon A; Wang T; Hilsenbeck SG; Chamness GC; Andò S; Fuqua SA
J Natl Cancer Inst; 2011 Apr; 103(7):538-52. PubMed ID: 21447808
[TBL] [Abstract][Full Text] [Related]
3. The Rho protein exchange factor Vav3 regulates vascular smooth muscle cell proliferation and migration.
Toumaniantz G; Ferland-McCollough D; Cario-Toumaniantz C; Pacaud P; Loirand G
Cardiovasc Res; 2010 Apr; 86(1):131-40. PubMed ID: 19969623
[TBL] [Abstract][Full Text] [Related]
4. Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
Onesto C; Shutes A; Picard V; Schweighoffer F; Der CJ
Methods Enzymol; 2008; 439():111-29. PubMed ID: 18374160
[TBL] [Abstract][Full Text] [Related]
5. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
Shutes A; Onesto C; Picard V; Leblond B; Schweighoffer F; Der CJ
J Biol Chem; 2007 Dec; 282(49):35666-78. PubMed ID: 17932039
[TBL] [Abstract][Full Text] [Related]
6. Targeting of Rac GTPases blocks the spread of intact human breast cancer.
Katz E; Sims AH; Sproul D; Caldwell H; Dixon MJ; Meehan RR; Harrison DJ
Oncotarget; 2012 Jun; 3(6):608-19. PubMed ID: 22689141
[TBL] [Abstract][Full Text] [Related]
7. p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells.
Zhuang T; Zhu J; Li Z; Lorent J; Zhao C; Dahlman-Wright K; Strömblad S
Oncotarget; 2015 Dec; 6(41):43853-68. PubMed ID: 26554417
[TBL] [Abstract][Full Text] [Related]
8. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase.
Montalvo-Ortiz BL; Castillo-Pichardo L; Hernández E; Humphries-Bickley T; De la Mota-Peynado A; Cubano LA; Vlaar CP; Dharmawardhane S
J Biol Chem; 2012 Apr; 287(16):13228-38. PubMed ID: 22383527
[TBL] [Abstract][Full Text] [Related]
9. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer.
Lee K; Liu Y; Mo JQ; Zhang J; Dong Z; Lu S
BMC Cancer; 2008 Jun; 8():158. PubMed ID: 18518979
[TBL] [Abstract][Full Text] [Related]
10. EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.
Sidarala V; Veluthakal R; Syeda K; Kowluru A
Cell Signal; 2015 Jun; 27(6):1159-67. PubMed ID: 25725286
[TBL] [Abstract][Full Text] [Related]
11. Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer.
Lyons LS; Rao S; Balkan W; Faysal J; Maiorino CA; Burnstein KL
Mol Endocrinol; 2008 Mar; 22(3):597-608. PubMed ID: 18079321
[TBL] [Abstract][Full Text] [Related]
12. RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells.
Sun J; Gaidosh G; Xu Y; Mookhtiar A; Man N; Cingaram PR; Blumenthal E; Shiekhattar R; Goka ET; Nimer SD; Lippman ME
Oncogene; 2021 Oct; 40(40):5950-5962. PubMed ID: 34373577
[TBL] [Abstract][Full Text] [Related]
13. Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERα-positive breast cancer.
Ciupek A; Rechoum Y; Gu G; Gelsomino L; Beyer AR; Brusco L; Covington KR; Tsimelzon A; Fuqua SA
Breast Cancer Res Treat; 2015 Nov; 154(2):225-37. PubMed ID: 26487496
[TBL] [Abstract][Full Text] [Related]
14. Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1/MAPK signaling.
Jiang K; Lu Q; Li Q; Ji Y; Chen W; Xue X
Int Immunopharmacol; 2017 Jan; 42():195-202. PubMed ID: 27930970
[TBL] [Abstract][Full Text] [Related]
15. The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.
Citterio C; Menacho-Márquez M; García-Escudero R; Larive RM; Barreiro O; Sánchez-Madrid F; Paramio JM; Bustelo XR
Sci Signal; 2012 Oct; 5(244):ra71. PubMed ID: 23033540
[TBL] [Abstract][Full Text] [Related]
16. Rac1 contributes to trastuzumab resistance of breast cancer cells: Rac1 as a potential therapeutic target for the treatment of trastuzumab-resistant breast cancer.
Dokmanovic M; Hirsch DS; Shen Y; Wu WJ
Mol Cancer Ther; 2009 Jun; 8(6):1557-69. PubMed ID: 19509242
[TBL] [Abstract][Full Text] [Related]
17. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells.
Gonzalez N; Cardama GA; Comin MJ; Segatori VI; Pifano M; Alonso DF; Gomez DE; Menna PL
Cell Signal; 2017 Jan; 30():154-161. PubMed ID: 27939839
[TBL] [Abstract][Full Text] [Related]
19. Rac1 signaling modulates BCL-6-mediated repression of gene transcription.
Barros P; Jordan P; Matos P
Mol Cell Biol; 2009 Aug; 29(15):4156-66. PubMed ID: 19487462
[TBL] [Abstract][Full Text] [Related]
20. ARHGAP17 inhibits pathological cyclic strain-induced apoptosis in human periodontal ligament fibroblasts via Rac1/Cdc42.
Wang L; Yang X; Wan L; Wang S; Pan J; Liu Y
Clin Exp Pharmacol Physiol; 2020 Sep; 47(9):1591-1599. PubMed ID: 32391922
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]