173 related articles for article (PubMed ID: 21119025)
1. A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Park MA; Hamed HA; Mitchell C; Cruickshanks N; Dash R; Allegood J; Dmitriev IP; Tye G; Ogretmen B; Spiegel S; Yacoub A; Grant S; Curiel DT; Fisher PB; Dent P
Mol Pharmacol; 2011 Mar; 79(3):368-80. PubMed ID: 21119025
[TBL] [Abstract][Full Text] [Related]
2. 17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species.
Walker T; Mitchell C; Park MA; Yacoub A; Rahmani M; Häussinger D; Reinehr R; Voelkel-Johnson C; Fisher PB; Grant S; Dent P
Mol Cancer Ther; 2010 May; 9(5):1378-95. PubMed ID: 20442308
[TBL] [Abstract][Full Text] [Related]
3. Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery.
Eulitt PJ; Park MA; Hossein H; Cruikshanks N; Yang C; Dmitriev IP; Yacoub A; Curiel DT; Fisher PB; Dent P
Cancer Biol Ther; 2010 Dec; 10(12):1290-305. PubMed ID: 20948318
[TBL] [Abstract][Full Text] [Related]
4. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
Park MA; Walker T; Martin AP; Allegood J; Vozhilla N; Emdad L; Sarkar D; Rahmani M; Graf M; Yacoub A; Koumenis C; Spiegel S; Curiel DT; Voelkel-Johnson C; Grant S; Fisher PB; Dent P
Mol Cancer Ther; 2009 May; 8(5):1280-91. PubMed ID: 19417161
[TBL] [Abstract][Full Text] [Related]
5. Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cells.
Hamed HA; Das SK; Sokhi UK; Park MA; Cruickshanks N; Archer K; Ogretmen B; Grant S; Sarkar D; Fisher PB; Dent P
Cancer Biol Ther; 2013 Nov; 14(11):1039-49. PubMed ID: 24025359
[TBL] [Abstract][Full Text] [Related]
6. 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.
Mitchell C; Park MA; Zhang G; Han SI; Harada H; Franklin RA; Yacoub A; Li PL; Hylemon PB; Grant S; Dent P
Mol Cancer Ther; 2007 Feb; 6(2):618-32. PubMed ID: 17308059
[TBL] [Abstract][Full Text] [Related]
7. Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Park MA; Zhang G; Mitchell C; Rahmani M; Hamed H; Hagan MP; Yacoub A; Curiel DT; Fisher PB; Grant S; Dent P
Mol Cancer Ther; 2008 Sep; 7(9):2633-48. PubMed ID: 18790746
[TBL] [Abstract][Full Text] [Related]
8. PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.
Yacoub A; Hamed HA; Allegood J; Mitchell C; Spiegel S; Lesniak MS; Ogretmen B; Dash R; Sarkar D; Broaddus WC; Grant S; Curiel DT; Fisher PB; Dent P
Cancer Res; 2010 Feb; 70(3):1120-9. PubMed ID: 20103619
[TBL] [Abstract][Full Text] [Related]
9. MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
Yacoub A; Mitchell C; Brannon J; Rosenberg E; Qiao L; McKinstry R; Linehan WM; Su ZS; Sarkar D; Lebedeva IV; Valerie K; Gopalkrishnan RV; Grant S; Fisher PB; Dent P
Mol Cancer Ther; 2003 Jul; 2(7):623-32. PubMed ID: 12883035
[TBL] [Abstract][Full Text] [Related]
10. Histone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.
Hamed HA; Yacoub A; Park MA; Archer K; Das SK; Sarkar D; Grant S; Fisher PB; Dent P
Mol Pharmacol; 2013 Aug; 84(2):171-81. PubMed ID: 23661648
[TBL] [Abstract][Full Text] [Related]
11. Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway.
Park MA; Mitchell C; Zhang G; Yacoub A; Allegood J; Häussinger D; Reinehr R; Larner A; Spiegel S; Fisher PB; Voelkel-Johnson C; Ogretmen B; Grant S; Dent P
Cancer Res; 2010 Aug; 70(15):6313-24. PubMed ID: 20631069
[TBL] [Abstract][Full Text] [Related]
12. Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis.
Sauane M; Su ZZ; Dash R; Liu X; Norris JS; Sarkar D; Lee SG; Allegood JC; Dent P; Spiegel S; Fisher PB
J Cell Physiol; 2010 Mar; 222(3):546-55. PubMed ID: 19937735
[TBL] [Abstract][Full Text] [Related]
13. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.
Park MA; Zhang G; Martin AP; Hamed H; Mitchell C; Hylemon PB; Graf M; Rahmani M; Ryan K; Liu X; Spiegel S; Norris J; Fisher PB; Grant S; Dent P
Cancer Biol Ther; 2008 Oct; 7(10):1648-62. PubMed ID: 18787411
[TBL] [Abstract][Full Text] [Related]
14. Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.
Lebedeva IV; Su ZZ; Sarkar D; Gopalkrishnan RV; Waxman S; Yacoub A; Dent P; Fisher PB
Oncogene; 2005 Jan; 24(4):585-96. PubMed ID: 15580305
[TBL] [Abstract][Full Text] [Related]
15. Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
Yacoub A; Liu R; Park MA; Hamed HA; Dash R; Schramm DN; Sarkar D; Dimitriev IP; Bell JK; Grant S; Farrell NP; Curiel DT; Fisher PB; Dent P
Mol Pharmacol; 2010 Feb; 77(2):298-310. PubMed ID: 19910452
[TBL] [Abstract][Full Text] [Related]
16. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
Azab B; Dash R; Das SK; Bhutia SK; Shen XN; Quinn BA; Sarkar S; Wang XY; Hedvat M; Dmitriev IP; Curiel DT; Grant S; Dent P; Reed JC; Pellecchia M; Sarkar D; Fisher PB
J Cell Physiol; 2012 May; 227(5):2145-53. PubMed ID: 21780116
[TBL] [Abstract][Full Text] [Related]
17. OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins.
Hamed HA; Yacoub A; Park MA; Eulitt P; Sarkar D; Dimitrie IP; Chen CS; Grant S; Curiel DT; Fisher PB; Dent P
Cancer Biol Ther; 2010 Apr; 9(7):526-36. PubMed ID: 20107314
[TBL] [Abstract][Full Text] [Related]
18. Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells.
Dash R; Dmitriev I; Su ZZ; Bhutia SK; Azab B; Vozhilla N; Yacoub A; Dent P; Curiel DT; Sarkar D; Fisher PB
Cancer Gene Ther; 2010 Jul; 17(7):447-56. PubMed ID: 20150932
[TBL] [Abstract][Full Text] [Related]
19. Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors.
Haviv YS; Blackwell JL; Kanerva A; Nagi P; Krasnykh V; Dmitriev I; Wang M; Naito S; Lei X; Hemminki A; Carey D; Curiel DT
Cancer Res; 2002 Aug; 62(15):4273-81. PubMed ID: 12154029
[TBL] [Abstract][Full Text] [Related]
20. MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
Yacoub A; Mitchell C; Hong Y; Gopalkrishnan RV; Su ZZ; Gupta P; Sauane M; Lebedeva IV; Curiel DT; Mahasreshti PJ; Rosenfeld MR; Broaddus WC; James CD; Grant S; Fisher PB; Dent P
Cancer Biol Ther; 2004 Aug; 3(8):739-51. PubMed ID: 15197348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
