BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 21123451)

  • 1. BCR/ABL stimulates WRN to promote survival and genomic instability.
    Slupianek A; Poplawski T; Jozwiakowski SK; Cramer K; Pytel D; Stoczynska E; Nowicki MO; Blasiak J; Skorski T
    Cancer Res; 2011 Feb; 71(3):842-51. PubMed ID: 21123451
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks.
    Sallmyr A; Tomkinson AE; Rassool FV
    Blood; 2008 Aug; 112(4):1413-23. PubMed ID: 18524993
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair.
    Cramer K; Nieborowska-Skorska M; Koptyra M; Slupianek A; Penserga ET; Eaves CJ; Aulitzky W; Skorski T
    Cancer Res; 2008 Sep; 68(17):6884-8. PubMed ID: 18757400
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BCR-ABL stimulates mutagenic homologous DNA double-strand break repair via the DNA-end-processing factor CtIP.
    Salles D; Mencalha AL; Ireno IC; Wiesmüller L; Abdelhay E
    Carcinogenesis; 2011 Jan; 32(1):27-34. PubMed ID: 20974687
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RAG enhances BCR-ABL1-positive leukemic cell growth through its endonuclease activity in vitro and in vivo.
    Yuan M; Wang Y; Qin M; Zhao X; Chen X; Li D; Miao Y; Otieno Odhiambo W; Liu H; Ma Y; Ji Y
    Cancer Sci; 2021 Jul; 112(7):2679-2691. PubMed ID: 33949040
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks.
    Nowicki MO; Falinski R; Koptyra M; Slupianek A; Stoklosa T; Gloc E; Nieborowska-Skorska M; Blasiak J; Skorski T
    Blood; 2004 Dec; 104(12):3746-53. PubMed ID: 15304390
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution.
    Cheng WH; von Kobbe C; Opresko PL; Fields KM; Ren J; Kufe D; Bohr VA
    Mol Cell Biol; 2003 Sep; 23(18):6385-95. PubMed ID: 12944467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis.
    Slupianek A; Hoser G; Majsterek I; Bronisz A; Malecki M; Blasiak J; Fishel R; Skorski T
    Mol Cell Biol; 2002 Jun; 22(12):4189-201. PubMed ID: 12024032
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway.
    Aggarwal M; Banerjee T; Sommers JA; Iannascoli C; Pichierri P; Shoemaker RH; Brosh RM
    Cancer Res; 2013 Sep; 73(17):5497-507. PubMed ID: 23867477
    [TBL] [Abstract][Full Text] [Related]  

  • 10. WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts.
    Zecevic A; Menard H; Gurel V; Hagan E; DeCaro R; Zhitkovich A
    Cell Cycle; 2009 Sep; 8(17):2769-78. PubMed ID: 19652551
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells.
    Rink L; Slupianek A; Stoklosa T; Nieborowska-Skorska M; Urbanska K; Seferynska I; Reiss K; Skorski T
    Blood; 2007 Jul; 110(2):651-60. PubMed ID: 17431132
    [TBL] [Abstract][Full Text] [Related]  

  • 12. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.
    Kusumoto R; Dawut L; Marchetti C; Wan Lee J; Vindigni A; Ramsden D; Bohr VA
    Biochemistry; 2008 Jul; 47(28):7548-56. PubMed ID: 18558713
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.
    Sturzenegger A; Burdova K; Kanagaraj R; Levikova M; Pinto C; Cejka P; Janscak P
    J Biol Chem; 2014 Sep; 289(39):27314-27326. PubMed ID: 25122754
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks.
    Kusumoto-Matsuo R; Ghosh D; Karmakar P; May A; Ramsden D; Bohr VA
    Aging (Albany NY); 2014 Jan; 6(1):70-81. PubMed ID: 24429382
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BCR/ABL downregulates DNA-PK(CS)-dependent and upregulates backup non-homologous end joining in leukemic cells.
    Poplawski T; Blasiak J
    Mol Biol Rep; 2010 Jun; 37(5):2309-15. PubMed ID: 19697154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability.
    Slupianek A; Falinski R; Znojek P; Stoklosa T; Flis S; Doneddu V; Pytel D; Synowiec E; Blasiak J; Bellacosa A; Skorski T
    Leukemia; 2013 Mar; 27(3):629-34. PubMed ID: 23047475
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting RAD51 phosphotyrosine-315 to prevent unfaithful recombination repair in BCR-ABL1 leukemia.
    Slupianek A; Dasgupta Y; Ren SY; Gurdek E; Donlin M; Nieborowska-Skorska M; Fleury F; Skorski T
    Blood; 2011 Jul; 118(4):1062-8. PubMed ID: 21653319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. WRN translocation from nucleolus to nucleoplasm is regulated by SIRT1 and required for DNA repair and the development of chemoresistance.
    Lee SY; Lee H; Kim ES; Park S; Lee J; Ahn B
    Mutat Res; 2015 Apr; 774():40-8. PubMed ID: 25801465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Promyelocytic leukemia protein interacts with werner syndrome helicase and regulates double-strand break repair in γ-irradiation-induced DNA damage responses.
    Liu J; Song Y; Qian J; Liu B; Dong Y; Tian B; Sun Z
    Biochemistry (Mosc); 2011 May; 76(5):550-4. PubMed ID: 21639834
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.