BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 21123822)

  • 1. Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model.
    Gunn WG; Krause U; Lee N; Gregory CA
    Blood; 2011 Feb; 117(5):1641-51. PubMed ID: 21123822
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy.
    Krause U; Harris S; Green A; Ylostalo J; Zeitouni S; Lee N; Gregory CA
    Proc Natl Acad Sci U S A; 2010 Mar; 107(9):4147-52. PubMed ID: 20150512
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GSK-3β inhibition promotes engraftment of ex vivo-expanded hematopoietic stem cells and modulates gene expression.
    Ko KH; Holmes T; Palladinetti P; Song E; Nordon R; O'Brien TA; Dolnikov A
    Stem Cells; 2011 Jan; 29(1):108-18. PubMed ID: 20960517
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss.
    Wang FS; Ko JY; Weng LH; Yeh DW; Ke HJ; Wu SL
    Life Sci; 2009 Nov; 85(19-20):685-92. PubMed ID: 19782693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small-molecule inhibitor of glycogen synthase kinase 3β 6-Bromoindirubin-3-oxime inhibits hematopoietic regeneration in stem cell recipient mice.
    Shen S; Xu N; Klamer G; Ko KH; Khoo M; Ma D; Moore J; O'Brien TA; Dolnikov A
    Stem Cells Dev; 2015 Mar; 24(6):724-36. PubMed ID: 25329250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 6-Bromoindirubin-3'-oxime promotes osteogenic differentiation of canine BMSCs through inhibition of GSK3β activity and activation of the Wnt/β-catenin signaling pathway.
    Zhao XE; Yang Z; Gao Z; Ge J; Wei Q; Ma B
    An Acad Bras Cienc; 2019 Mar; 91(1):e20180459. PubMed ID: 30916158
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glycogen synthase kinase--3β inhibitors suppress leukemia cell growth.
    Song EY; Palladinetti P; Klamer G; Ko KH; Lindeman R; O'Brien TA; Dolnikov A
    Exp Hematol; 2010 Oct; 38(10):908-921.e1. PubMed ID: 20540984
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GSK-3β inhibition promotes early engraftment of ex vivo-expanded haematopoietic stem cells.
    Dolnikov A; Xu N; Shen S; Song E; Holmes T; Klamer G; O'Brien TA
    Cell Prolif; 2014 Apr; 47(2):113-23. PubMed ID: 24517125
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.
    Briolotti P; Chaloin L; Balaguer P; Da Silva F; Tománková V; Pascussi JM; Duret C; Fabre JM; Ramos J; Klieber S; Maurel P; Daujat-Chavanieu M; Gerbal-Chaloin S
    Toxicol Sci; 2015 Nov; 148(1):261-75. PubMed ID: 26259606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GSK-3β inhibition preserves naive T cell phenotype in bone marrow reconstituted mice.
    Shen S; Klamer G; Xu N; O'Brien TA; Dolnikov A
    Exp Hematol; 2013 Dec; 41(12):1016-27.e1. PubMed ID: 24018603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo.
    Edwards CM; Edwards JR; Lwin ST; Esparza J; Oyajobi BO; McCluskey B; Munoz S; Grubbs B; Mundy GR
    Blood; 2008 Mar; 111(5):2833-42. PubMed ID: 18094333
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.
    Sinha D; Wang Z; Ruchalski KL; Levine JS; Krishnan S; Lieberthal W; Schwartz JH; Borkan SC
    Am J Physiol Renal Physiol; 2005 Apr; 288(4):F703-13. PubMed ID: 15572521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The new indirubin derivative inhibitors of glycogen synthase kinase-3, 6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons.
    Martin L; Magnaudeix A; Wilson CM; Yardin C; Terro F
    J Neurosci Res; 2011 Nov; 89(11):1802-11. PubMed ID: 21826701
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of glycogen synthase kinase-3beta downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A.
    Martin L; Magnaudeix A; Esclaire F; Yardin C; Terro F
    Brain Res; 2009 Feb; 1252():66-75. PubMed ID: 19071093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.
    Yang J; He J; Wang J; Cao Y; Ling J; Qian J; Lu Y; Li H; Zheng Y; Lan Y; Hong S; Matthews J; Starbuck MW; Navone NM; Orlowski RZ; Lin P; Kwak LW; Yi Q
    Leukemia; 2012 Sep; 26(9):2114-23. PubMed ID: 22425892
    [TBL] [Abstract][Full Text] [Related]  

  • 16. How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow.
    Gregory CA; Gunn WG; Reyes E; Smolarz AJ; Munoz J; Spees JL; Prockop DJ
    Ann N Y Acad Sci; 2005 May; 1049():97-106. PubMed ID: 15965110
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glycogen synthase kinase-3beta inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth.
    Holmes T; O'Brien TA; Knight R; Lindeman R; Shen S; Song E; Symonds G; Dolnikov A
    Stem Cells; 2008 May; 26(5):1288-97. PubMed ID: 18323411
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo.
    Kulkarni NH; Onyia JE; Zeng Q; Tian X; Liu M; Halladay DL; Frolik CA; Engler T; Wei T; Kriauciunas A; Martin TJ; Sato M; Bryant HU; Ma YL
    J Bone Miner Res; 2006 Jun; 21(6):910-20. PubMed ID: 16753022
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Delayed treatment of 6-Bromoindirubin-3'-oxime stimulates neurogenesis and functional recovery after focal ischemic stroke in mice.
    Wang LL; Li J; Gu X; Wei L; Yu SP
    Int J Dev Neurosci; 2017 Apr; 57():77-84. PubMed ID: 28111255
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced Wnt/β-catenin signalling during tooth morphogenesis impedes cell differentiation and leads to alterations in the structure and mineralisation of the adult tooth.
    Aurrekoetxea M; Lopez J; García P; Ibarretxe G; Unda F
    Biol Cell; 2012 Oct; 104(10):603-17. PubMed ID: 22671936
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.