BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 21126175)

  • 1. Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice.
    Rajasekaran NS; Varadharaj S; Khanderao GD; Davidson CJ; Kannan S; Firpo MA; Zweier JL; Benjamin IJ
    Antioxid Redox Signal; 2011 Mar; 14(6):957-71. PubMed ID: 21126175
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Restoration of Nrf2 Signaling Normalizes the Regenerative Niche.
    Soares MA; Cohen OD; Low YC; Sartor RA; Ellison T; Anil U; Anzai L; Chang JB; Saadeh PB; Rabbani PS; Ceradini DJ
    Diabetes; 2016 Mar; 65(3):633-46. PubMed ID: 26647385
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium.
    Muthusamy VR; Kannan S; Sadhaasivam K; Gounder SS; Davidson CJ; Boeheme C; Hoidal JR; Wang L; Rajasekaran NS
    Free Radic Biol Med; 2012 Jan; 52(2):366-76. PubMed ID: 22051043
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.
    Reisman SA; Yeager RL; Yamamoto M; Klaassen CD
    Toxicol Sci; 2009 Mar; 108(1):35-47. PubMed ID: 19129213
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis.
    Hou Y; Xue P; Bai Y; Liu D; Woods CG; Yarborough K; Fu J; Zhang Q; Sun G; Collins S; Chan JY; Yamamoto M; Andersen ME; Pi J
    Free Radic Biol Med; 2012 Jan; 52(2):462-72. PubMed ID: 22138520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity.
    Williamson TP; Johnson DA; Johnson JA
    Neurotoxicology; 2012 Jun; 33(3):272-9. PubMed ID: 22342405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2).
    Li W; Liu H; Zhou JS; Cao JF; Zhou XB; Choi AM; Chen ZH; Shen HH
    J Biol Chem; 2012 Jun; 287(25):20922-30. PubMed ID: 22547061
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Serine/threonine kinase 3 promotes oxidative stress and mitochondrial damage in septic cardiomyopathy through inducing Kelch-like ECH-associated protein 1 phosphorylation and nuclear factor erythroid 2-related factor 2 degradation.
    Zhu H; Dai Z; Liu X; Zhou H; Wang Y
    Int J Biol Sci; 2023; 19(5):1369-1381. PubMed ID: 37056939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress.
    Nguyen T; Nioi P; Pickett CB
    J Biol Chem; 2009 May; 284(20):13291-5. PubMed ID: 19182219
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.
    Sun Z; Wu T; Zhao F; Lau A; Birch CM; Zhang DD
    Mol Cell Biol; 2011 May; 31(9):1800-11. PubMed ID: 21383067
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice.
    Rajasekaran NS; Connell P; Christians ES; Yan LJ; Taylor RP; Orosz A; Zhang XQ; Stevenson TJ; Peshock RM; Leopold JA; Barry WH; Loscalzo J; Odelberg SJ; Benjamin IJ
    Cell; 2007 Aug; 130(3):427-39. PubMed ID: 17693254
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disruption of Nrf2/ARE signaling impairs antioxidant mechanisms and promotes cell degradation pathways in aged skeletal muscle.
    Miller CJ; Gounder SS; Kannan S; Goutam K; Muthusamy VR; Firpo MA; Symons JD; Paine R; Hoidal JR; Rajasekaran NS
    Biochim Biophys Acta; 2012 Jun; 1822(6):1038-50. PubMed ID: 22366763
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1.
    Ren X; Yu J; Guo L; Ma H
    Exp Cell Res; 2020 Jun; 391(1):111988. PubMed ID: 32251645
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis.
    Kong X; Thimmulappa R; Craciun F; Harvey C; Singh A; Kombairaju P; Reddy SP; Remick D; Biswal S
    Am J Respir Crit Care Med; 2011 Oct; 184(8):928-38. PubMed ID: 21799073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
    Komatsu M; Kurokawa H; Waguri S; Taguchi K; Kobayashi A; Ichimura Y; Sou YS; Ueno I; Sakamoto A; Tong KI; Kim M; Nishito Y; Iemura S; Natsume T; Ueno T; Kominami E; Motohashi H; Tanaka K; Yamamoto M
    Nat Cell Biol; 2010 Mar; 12(3):213-23. PubMed ID: 20173742
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis.
    Sun X; Zuo H; Liu C; Yang Y
    Int J Mol Med; 2016 Oct; 38(4):1303-11. PubMed ID: 27573160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation.
    Niture SK; Jaiswal AK
    J Biol Chem; 2010 Nov; 285(47):36865-75. PubMed ID: 20864537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger.
    Wang J; Shanmugam A; Markand S; Zorrilla E; Ganapathy V; Smith SB
    Free Radic Biol Med; 2015 Sep; 86():25-36. PubMed ID: 25920363
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NF-κB and Keap1 Interaction Represses Nrf2-Mediated Antioxidant Response in Rabbit Hemorrhagic Disease Virus Infection.
    Hu B; Wei H; Song Y; Chen M; Fan Z; Qiu R; Zhu W; Xu W; Wang F
    J Virol; 2020 May; 94(10):. PubMed ID: 32161178
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The oncoprotein HBXIP competitively binds KEAP1 to activate NRF2 and enhance breast cancer cell growth and metastasis.
    Zhou XL; Zhu CY; Wu ZG; Guo X; Zou W
    Oncogene; 2019 May; 38(21):4028-4046. PubMed ID: 30692632
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.