BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 21126318)

  • 1. Activation, regulation, and inhibition of DYRK1A.
    Becker W; Sippl W
    FEBS J; 2011 Jan; 278(2):246-56. PubMed ID: 21126318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
    Göckler N; Jofre G; Papadopoulos C; Soppa U; Tejedor FJ; Becker W
    FEBS J; 2009 Nov; 276(21):6324-37. PubMed ID: 19796173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
    Adayev T; Chen-Hwang MC; Murakami N; Lee E; Bolton DC; Hwang YW
    Biochemistry; 2007 Jun; 46(25):7614-24. PubMed ID: 17536841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of Dyrk1A kinase activity by 14-3-3.
    Kim D; Won J; Shin DW; Kang J; Kim YJ; Choi SY; Hwang MK; Jeong BW; Kim GS; Joe CO; Chung SH; Song WJ
    Biochem Biophys Res Commun; 2004 Oct; 323(2):499-504. PubMed ID: 15369779
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MNB/DYRK1A as a multiple regulator of neuronal development.
    Tejedor FJ; Hämmerle B
    FEBS J; 2011 Jan; 278(2):223-35. PubMed ID: 21156027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.
    Seifert A; Allan LA; Clarke PR
    FEBS J; 2008 Dec; 275(24):6268-80. PubMed ID: 19016842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of dual specificity kinase activity of DYRK1A.
    Walte A; Rüben K; Birner-Gruenberger R; Preisinger C; Bamberg-Lemper S; Hilz N; Bracher F; Becker W
    FEBS J; 2013 Sep; 280(18):4495-511. PubMed ID: 23809146
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein.
    Bescond M; Rahmani Z
    Int J Biochem Cell Biol; 2005 Apr; 37(4):775-83. PubMed ID: 15694837
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    Ryoo SR; Cho HJ; Lee HW; Jeong HK; Radnaabazar C; Kim YS; Kim MJ; Son MY; Seo H; Chung SH; Song WJ
    J Neurochem; 2008 Mar; 104(5):1333-44. PubMed ID: 18005339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
    Ryu YS; Park SY; Jung MS; Yoon SH; Kwen MY; Lee SY; Choi SH; Radnaabazar C; Kim MK; Kim H; Kim K; Song WJ; Chung SH
    J Neurochem; 2010 Nov; 115(3):574-84. PubMed ID: 20456003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.
    Coutadeur S; Benyamine H; Delalonde L; de Oliveira C; Leblond B; Foucourt A; Besson T; Casagrande AS; Taverne T; Girard A; Pando MP; Désiré L
    J Neurochem; 2015 May; 133(3):440-51. PubMed ID: 25556849
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice.
    Mazur-Kolecka B; Golabek A; Kida E; Rabe A; Hwang YW; Adayev T; Wegiel J; Flory M; Kaczmarski W; Marchi E; Frackowiak J
    J Neurosci Res; 2012 May; 90(5):999-1010. PubMed ID: 22252917
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
    Jarhad DB; Mashelkar KK; Kim HR; Noh M; Jeong LS
    J Med Chem; 2018 Nov; 61(22):9791-9810. PubMed ID: 29985601
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Library-based discovery of DYRK1A/CLK1 inhibitors from natural product extracts.
    Grabher P; Durieu E; Kouloura E; Halabalaki M; Skaltsounis LA; Meijer L; Hamburger M; Potterat O
    Planta Med; 2012 Jun; 78(10):951-6. PubMed ID: 22673832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.
    Toiber D; Azkona G; Ben-Ari S; Torán N; Soreq H; Dierssen M
    Neurobiol Dis; 2010 Oct; 40(1):348-59. PubMed ID: 20600907
    [TBL] [Abstract][Full Text] [Related]  

  • 16. QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitors.
    Koo KA; Kim ND; Chon YS; Jung MS; Lee BJ; Kim JH; Song WJ
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2324-8. PubMed ID: 19282176
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
    Rüben K; Wurzlbauer A; Walte A; Sippl W; Bracher F; Becker W
    PLoS One; 2015; 10(7):e0132453. PubMed ID: 26192590
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors.
    Czarna A; Wang J; Zelencova D; Liu Y; Deng X; Choi HG; Zhang T; Zhou W; Chang JW; Kildalsen H; Seternes OM; Gray NS; Engh RA; Rothweiler U
    J Med Chem; 2018 Sep; 61(17):7560-7572. PubMed ID: 30095246
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Small Molecule Inhibitors of DYRK1A Identified by Computational and Experimental Approaches.
    Yoon HR; Balupuri A; Choi KE; Kang NS
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32957634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A).
    Adayev T; Wegiel J; Hwang YW
    Arch Biochem Biophys; 2011 Mar; 507(2):212-8. PubMed ID: 21185805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.