108 related articles for article (PubMed ID: 21126842)
1. A rapid vesicle electrokinetic chromatography method for the in vitro prediction of non-specific binding for potential PET ligands.
Jiang Z; Reilly J; Everatt B; Briard E
J Pharm Biomed Anal; 2011 Mar; 54(4):722-9. PubMed ID: 21126842
[TBL] [Abstract][Full Text] [Related]
2. Label-free assay for the assessment of nonspecific binding of positron emission tomography tracer candidates.
Assmus F; Seelig A; Gobbi L; Borroni E; Glaentzlin P; Fischer H
Eur J Pharm Sci; 2015 Nov; 79():27-35. PubMed ID: 26341407
[TBL] [Abstract][Full Text] [Related]
3. Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers?
Joshi EM; Need A; Schaus J; Chen Z; Benesh D; Mitch C; Morton S; Raub TJ; Phebus L; Barth V
ACS Chem Neurosci; 2014 Dec; 5(12):1154-63. PubMed ID: 25247893
[TBL] [Abstract][Full Text] [Related]
4. Investigation of vesicle electrokinetic chromatography as an in vitro assay for the estimation of intestinal permeability of pharmaceutical drug candidates.
Pascoe RJ; Masucci JA; Foley JP
Electrophoresis; 2006 Feb; 27(4):793-804. PubMed ID: 16411277
[TBL] [Abstract][Full Text] [Related]
5. A method for rapidly predicting drug tissue distribution using surfactant vesicle electrokinetic chromatography.
Jiang Z; Reilly J; Everatt B
Electrophoresis; 2008 Sep; 29(17):3674-84. PubMed ID: 18803182
[TBL] [Abstract][Full Text] [Related]
6. Developing a cassette microdosing approach to enhance the throughput of PET imaging agent screening.
Xiao H; Sun M; Zhao R; Hong H; Zhang A; Zhang S; Liu F; Zhang Y; Liu Y; Zhu L; Kung HF; Qiao J
J Pharm Biomed Anal; 2018 May; 154():48-56. PubMed ID: 29533858
[TBL] [Abstract][Full Text] [Related]
7. Novel amphiphilic probes for [18F]-radiolabeling preformed liposomes and determination of liposomal trafficking by positron emission tomography.
Urakami T; Akai S; Katayama Y; Harada N; Tsukada H; Oku N
J Med Chem; 2007 Dec; 50(26):6454-7. PubMed ID: 18052025
[TBL] [Abstract][Full Text] [Related]
8. Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand.
Zhang L; Villalobos A; Beck EM; Bocan T; Chappie TA; Chen L; Grimwood S; Heck SD; Helal CJ; Hou X; Humphrey JM; Lu J; Skaddan MB; McCarthy TJ; Verhoest PR; Wager TT; Zasadny K
J Med Chem; 2013 Jun; 56(11):4568-79. PubMed ID: 23651455
[TBL] [Abstract][Full Text] [Related]
9. Radiotracer properties determined by high performance liquid chromatography: a potential tool for brain radiotracer discovery.
Tavares AA; Lewsey J; Dewar D; Pimlott SL
Nucl Med Biol; 2012 Jan; 39(1):127-35. PubMed ID: 21958855
[TBL] [Abstract][Full Text] [Related]
10. Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.
Mabondzo A; Bottlaender M; Guyot AC; Tsaouin K; Deverre JR; Balimane PV
Mol Pharm; 2010 Oct; 7(5):1805-15. PubMed ID: 20795735
[TBL] [Abstract][Full Text] [Related]
11. A Comparative Study of in vitro Assays for Predicting the Nonspecific Binding of PET Imaging Agents in vivo.
Gobbi L; Mercier J; Bang-Andersen B; Nicolas JM; Reilly J; Wagner B; Whitehead D; Briard E; Maguire RP; Borroni E; Auberson YP
ChemMedChem; 2020 Apr; 15(7):585-592. PubMed ID: 31797561
[TBL] [Abstract][Full Text] [Related]
12. Chromatography approaches for early screening of the phospholipidosis-inducing potential of pharmaceuticals.
Jiang Z; Reilly J
J Pharm Biomed Anal; 2012 Mar; 61():184-90. PubMed ID: 22200505
[TBL] [Abstract][Full Text] [Related]
13. Analysis of liposomes by capillary electrophoresis and their use as carrier in electrokinetic chromatography.
Bilek G; Kremser L; Blaas D; Kenndler E
J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Sep; 841(1-2):38-51. PubMed ID: 16682264
[TBL] [Abstract][Full Text] [Related]
14. A biomathematical modeling approach to central nervous system radioligand discovery and development.
Guo Q; Brady M; Gunn RN
J Nucl Med; 2009 Oct; 50(10):1715-23. PubMed ID: 19759115
[TBL] [Abstract][Full Text] [Related]
15. Radioligand development for molecular imaging of the central nervous system with positron emission tomography.
Honer M; Gobbi L; Martarello L; Comley RA
Drug Discov Today; 2014 Dec; 19(12):1936-44. PubMed ID: 25173703
[TBL] [Abstract][Full Text] [Related]
16. Identifying novel radiotracers for PET imaging of the brain: application of LC-MS/MS to tracer identification.
Barth V; Need A
ACS Chem Neurosci; 2014 Dec; 5(12):1148-53. PubMed ID: 24828747
[TBL] [Abstract][Full Text] [Related]
17. Liposome electrokinetic chromatography based in vitro model for early screening of the drug-induced phospholipidosis risk.
Wang T; Feng Y; Jin X; Fan X; Crommen J; Jiang Z
J Pharm Biomed Anal; 2014 Aug; 96():263-71. PubMed ID: 24814828
[TBL] [Abstract][Full Text] [Related]
18. Ligand Specific Efficiency (LSE) Index for PET Tracer Optimization.
Auberson YP; Briard E; Sykes D; Reilly J; Healy M
ChemMedChem; 2016 Jul; 11(13):1415-27. PubMed ID: 27193393
[TBL] [Abstract][Full Text] [Related]
19. PET radiotracers: crossing the blood-brain barrier and surviving metabolism.
Pike VW
Trends Pharmacol Sci; 2009 Aug; 30(8):431-40. PubMed ID: 19616318
[TBL] [Abstract][Full Text] [Related]
20. 11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors.
Horti AG; Fan H; Kuwabara H; Hilton J; Ravert HT; Holt DP; Alexander M; Kumar A; Rahmim A; Scheffel U; Wong DF; Dannals RF
J Nucl Med; 2006 Oct; 47(10):1689-96. PubMed ID: 17015906
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
