These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Prelamin A farnesylation and progeroid syndromes. Young SG; Meta M; Yang SH; Fong LG J Biol Chem; 2006 Dec; 281(52):39741-5. PubMed ID: 17090536 [TBL] [Abstract][Full Text] [Related]
4. Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes. Toth JI; Yang SH; Qiao X; Beigneux AP; Gelb MH; Moulson CL; Miner JH; Young SG; Fong LG Proc Natl Acad Sci U S A; 2005 Sep; 102(36):12873-8. PubMed ID: 16129834 [TBL] [Abstract][Full Text] [Related]
5. Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartment. Barrowman J; Hamblet C; George CM; Michaelis S Mol Biol Cell; 2008 Dec; 19(12):5398-408. PubMed ID: 18923140 [TBL] [Abstract][Full Text] [Related]
6. Involvement of prelamin A in laminopathies. Maraldi NM; Lattanzi G Crit Rev Eukaryot Gene Expr; 2007; 17(4):317-34. PubMed ID: 17725496 [TBL] [Abstract][Full Text] [Related]
7. Type B mandibuloacral dysplasia with congenital myopathy due to homozygous ZMPSTE24 missense mutation. Ben Yaou R; Navarro C; Quijano-Roy S; Bertrand AT; Massart C; De Sandre-Giovannoli A; Cadiñanos J; Mamchaoui K; Butler-Browne G; Estournet B; Richard P; Barois A; Lévy N; Bonne G Eur J Hum Genet; 2011 Jun; 19(6):647-54. PubMed ID: 21267004 [TBL] [Abstract][Full Text] [Related]
8. Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24. Barrowman J; Hamblet C; Kane MS; Michaelis S PLoS One; 2012; 7(2):e32120. PubMed ID: 22355414 [TBL] [Abstract][Full Text] [Related]
9. Emerin-prelamin A interplay in human fibroblasts. Capanni C; Del Coco R; Mattioli E; Camozzi D; Columbaro M; Schena E; Merlini L; Squarzoni S; Maraldi NM; Lattanzi G Biol Cell; 2009 Sep; 101(9):541-54. PubMed ID: 19323649 [TBL] [Abstract][Full Text] [Related]
10. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome. Mallampalli MP; Huyer G; Bendale P; Gelb MH; Michaelis S Proc Natl Acad Sci U S A; 2005 Oct; 102(40):14416-21. PubMed ID: 16186497 [TBL] [Abstract][Full Text] [Related]
11. Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria. Ibrahim MX; Sayin VI; Akula MK; Liu M; Fong LG; Young SG; Bergo MO Science; 2013 Jun; 340(6138):1330-3. PubMed ID: 23686339 [TBL] [Abstract][Full Text] [Related]
12. A newly identified splice site mutation in ZMPSTE24 causes restrictive dermopathy in the Middle East. Sander CS; Salman N; van Geel M; Broers JL; Al-Rahmani A; Chedid F; Hausser I; Oji V; Al Nuaimi K; Berger TG; Verstraeten VL Br J Dermatol; 2008 Sep; 159(4):961-7. PubMed ID: 18671782 [TBL] [Abstract][Full Text] [Related]
14. Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria. Dominici S; Fiori V; Magnani M; Schena E; Capanni C; Camozzi D; D'Apice MR; Le Dour C; Auclair M; Caron M; Novelli G; Vigouroux C; Maraldi NM; Lattanzi G Eur J Histochem; 2009; 53(1):43-52. PubMed ID: 19351612 [TBL] [Abstract][Full Text] [Related]
15. Rapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics. Cenni V; Capanni C; Mattioli E; Columbaro M; Wehnert M; Ortolani M; Fini M; Novelli G; Bertacchini J; Maraldi NM; Marmiroli S; D'Apice MR; Prencipe S; Squarzoni S; Lattanzi G Aging (Albany NY); 2014 Sep; 6(9):755-70. PubMed ID: 25324471 [TBL] [Abstract][Full Text] [Related]
16. Lamins are rapamycin targets that impact human longevity: a study in centenarians. Lattanzi G; Ortolani M; Columbaro M; Prencipe S; Mattioli E; Lanzarini C; Maraldi NM; Cenni V; Garagnani P; Salvioli S; Storci G; Bonafè M; Capanni C; Franceschi C J Cell Sci; 2014 Jan; 127(Pt 1):147-57. PubMed ID: 24155329 [TBL] [Abstract][Full Text] [Related]
17. Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging. Ragnauth CD; Warren DT; Liu Y; McNair R; Tajsic T; Figg N; Shroff R; Skepper J; Shanahan CM Circulation; 2010 May; 121(20):2200-10. PubMed ID: 20458013 [TBL] [Abstract][Full Text] [Related]
18. Investigating the purpose of prelamin A processing. Davies BS; Coffinier C; Yang SH; Barnes RH; Jung HJ; Young SG; Fong LG Nucleus; 2011; 2(1):4-9. PubMed ID: 21647293 [TBL] [Abstract][Full Text] [Related]
19. Drugs affecting prelamin A processing: effects on heterochromatin organization. Mattioli E; Columbaro M; Capanni C; Santi S; Maraldi NM; D'Apice MR; Novelli G; Riccio M; Squarzoni S; Foisner R; Lattanzi G Exp Cell Res; 2008 Feb; 314(3):453-62. PubMed ID: 18093584 [TBL] [Abstract][Full Text] [Related]
20. Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Fong LG; Ng JK; Meta M; Coté N; Yang SH; Stewart CL; Sullivan T; Burghardt A; Majumdar S; Reue K; Bergo MO; Young SG Proc Natl Acad Sci U S A; 2004 Dec; 101(52):18111-6. PubMed ID: 15608054 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]