These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 21130715)

  • 1. When cleavage is not attractive: non-catalytic inhibition of ubiquitin chains at DNA double-strand breaks by OTUB1.
    Blackford AN; Stewart GS
    DNA Repair (Amst); 2011 Feb; 10(2):245-9. PubMed ID: 21130715
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.
    Nakada S; Tai I; Panier S; Al-Hakim A; Iemura S; Juang YC; O'Donnell L; Kumakubo A; Munro M; Sicheri F; Gingras AC; Natsume T; Suda T; Durocher D
    Nature; 2010 Aug; 466(7309):941-6. PubMed ID: 20725033
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.
    Mosbech A; Lukas C; Bekker-Jensen S; Mailand N
    J Biol Chem; 2013 Jun; 288(23):16579-16587. PubMed ID: 23615962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mechanism of OTUB1-mediated inhibition of ubiquitination.
    Wiener R; Zhang X; Wang T; Wolberger C
    Nature; 2012 Feb; 483(7391):618-22. PubMed ID: 22367539
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
    Thorslund T; Ripplinger A; Hoffmann S; Wild T; Uckelmann M; Villumsen B; Narita T; Sixma TK; Choudhary C; Bekker-Jensen S; Mailand N
    Nature; 2015 Nov; 527(7578):389-93. PubMed ID: 26503038
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
    Hodge CD; Ismail IH; Edwards RA; Hura GL; Xiao AT; Tainer JA; Hendzel MJ; Glover JN
    J Biol Chem; 2016 Apr; 291(18):9396-410. PubMed ID: 26903517
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.
    Sato Y; Yamagata A; Goto-Ito S; Kubota K; Miyamoto R; Nakada S; Fukai S
    J Biol Chem; 2012 Jul; 287(31):25860-8. PubMed ID: 22679021
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A High-Throughput Screening Strategy for Development of RNF8-Ubc13 Protein-Protein Interaction Inhibitors.
    Weber E; Rothenaigner I; Brandner S; Hadian K; Schorpp K
    SLAS Discov; 2017 Mar; 22(3):316-323. PubMed ID: 27909234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
    Campbell SJ; Edwards RA; Leung CC; Neculai D; Hodge CD; Dhe-Paganon S; Glover JN
    J Biol Chem; 2012 Jul; 287(28):23900-10. PubMed ID: 22589545
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA repair: Blocking ubiquitin transfer.
    Rose A; Schlieker C
    Nature; 2010 Aug; 466(7309):929-30. PubMed ID: 20725029
    [No Abstract]   [Full Text] [Related]  

  • 11. OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
    Juang YC; Landry MC; Sanches M; Vittal V; Leung CC; Ceccarelli DF; Mateo AR; Pruneda JN; Mao DY; Szilard RK; Orlicky S; Munro M; Brzovic PS; Klevit RE; Sicheri F; Durocher D
    Mol Cell; 2012 Feb; 45(3):384-97. PubMed ID: 22325355
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.
    Zhao H; Zhu M; Dou G; Zhao H; Zhu B; Li J; Liao J; Xu X
    Cell Cycle; 2014; 13(11):1777-87. PubMed ID: 24732096
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for role of ring finger protein RNF168 RING domain.
    Zhang X; Chen J; Wu M; Wu H; Arokiaraj AW; Wang C; Zhang W; Tao Y; Huen MS; Zang J
    Cell Cycle; 2013 Jan; 12(2):312-21. PubMed ID: 23255131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
    Wiener R; DiBello AT; Lombardi PM; Guzzo CM; Zhang X; Matunis MJ; Wolberger C
    Nat Struct Mol Biol; 2013 Sep; 20(9):1033-9. PubMed ID: 23955022
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.
    Mandemaker IK; van Cuijk L; Janssens RC; Lans H; Bezstarosti K; Hoeijmakers JH; Demmers JA; Vermeulen W; Marteijn JA
    Sci Rep; 2017 Nov; 7(1):15353. PubMed ID: 29127375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology.
    Windheim M; Peggie M; Cohen P
    Biochem J; 2008 Feb; 409(3):723-9. PubMed ID: 18042044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks.
    Shao G; Lilli DR; Patterson-Fortin J; Coleman KA; Morrissey DE; Greenberg RA
    Proc Natl Acad Sci U S A; 2009 Mar; 106(9):3166-71. PubMed ID: 19202061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage.
    Chen J; Feng W; Jiang J; Deng Y; Huen MS
    J Biol Chem; 2012 Aug; 287(33):27715-22. PubMed ID: 22733822
    [TBL] [Abstract][Full Text] [Related]  

  • 19. OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination.
    Pasupala N; Morrow ME; Que LT; Malynn BA; Ma A; Wolberger C
    J Biol Chem; 2018 Nov; 293(47):18285-18295. PubMed ID: 30282802
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage.
    Ramaekers CH; van den Beucken T; Bristow RG; Chiu RK; Durocher D; Wouters BG
    PLoS One; 2014; 9(2):e89997. PubMed ID: 24587176
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.