These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 21131779)

  • 1. Microtubule-targeting-compound PBOX-15 radiosensitizes cancer cells in vitro.
    Forde JC; Maginn EN; McNamara G; Martin LM; Campiani G; Williams DC; Zisterer D; McElligott AM; Lawler M; Lynch TH; Hollywood D; Marignol L
    Cancer Biol Ther; 2011 Feb; 11(4):421-8. PubMed ID: 21131779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells.
    Nathwani SM; Cloonan SM; Stronach M; Campiani G; Lawler M; Williams DC; Zisterer DM
    Oncol Rep; 2010 Dec; 24(6):1499-507. PubMed ID: 21042745
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition.
    Jonsson M; Ragnum HB; Julin CH; Yeramian A; Clancy T; Frikstad KM; Seierstad T; Stokke T; Matias-Guiu X; Ree AH; Flatmark K; Lyng H
    Br J Cancer; 2016 Oct; 115(8):929-939. PubMed ID: 27599042
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The natural compound gambogic acid radiosensitizes nasopharyngeal carcinoma cells under hypoxic conditions.
    Yang M; Yang Y; Cui H; Guan Z; Yang Y; Zhang H; Chen X; Zhu H; Yang X; Cai J; Cheng H; Sun X
    Tumori; 2016; 102(2):135-43. PubMed ID: 26357974
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines.
    Mulligan JM; Greene LM; Cloonan S; Mc Gee MM; Onnis V; Campiani G; Fattorusso C; Lawler M; Williams DC; Zisterer DM
    Mol Pharmacol; 2006 Jul; 70(1):60-70. PubMed ID: 16571652
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nutlin-3 radiosensitizes hypoxic prostate cancer cells independent of p53.
    Supiot S; Hill RP; Bristow RG
    Mol Cancer Ther; 2008 Apr; 7(4):993-9. PubMed ID: 18413812
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of hypoxia-inducible factor-1 alpha radiosensitized MG-63 human osteosarcoma cells in vitro.
    Jin Z; Aixi Y; Baiwen Q; Zonghuan L; Xiang H
    Tumori; 2015; 101(5):578-84. PubMed ID: 26350185
    [TBL] [Abstract][Full Text] [Related]  

  • 8. STI-571 (imatinib mesylate) enhances the apoptotic efficacy of pyrrolo-1,5-benzoxazepine-6, a novel microtubule-targeting agent, in both STI-571-sensitive and -resistant Bcr-Abl-positive human chronic myeloid leukemia cells.
    Greene LM; Kelly L; Onnis V; Campiani G; Lawler M; Williams DC; Zisterer DM
    J Pharmacol Exp Ther; 2007 Apr; 321(1):288-97. PubMed ID: 17202400
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells.
    Maginn EN; Browne PV; Hayden P; Vandenberghe E; MacDonagh B; Evans P; Goodyer M; Tewari P; Campiani G; Butini S; Williams DC; Zisterer DM; Lawler MP; McElligott AM
    Br J Cancer; 2011 Jan; 104(2):281-9. PubMed ID: 21179037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells.
    Nathwani SM; Butler S; Fayne D; McGovern NN; Sarkadi B; Meegan MJ; Lloyd DG; Campiani G; Lawler M; Williams DC; Zisterer DM
    Cancer Chemother Pharmacol; 2010 Aug; 66(3):585-96. PubMed ID: 20020128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia.
    McElligott AM; Maginn EN; Greene LM; McGuckin S; Hayat A; Browne PV; Butini S; Campiani G; Catherwood MA; Vandenberghe E; Williams DC; Zisterer DM; Lawler M
    Cancer Res; 2009 Nov; 69(21):8366-75. PubMed ID: 19826055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. KNK437, abrogates hypoxia-induced radioresistance by dual targeting of the AKT and HIF-1α survival pathways.
    Oommen D; Prise KM
    Biochem Biophys Res Commun; 2012 May; 421(3):538-43. PubMed ID: 22521642
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells.
    Lysaght J; Verma NK; Maginn EN; Ryan JM; Campiani G; Zisterer DM; Williams DC; Browne PV; Lawler MP; McElligott AM
    Int J Oncol; 2013 Jan; 42(1):239-46. PubMed ID: 23135704
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells.
    Fiore D; Proto MC; Pisanti S; Picardi P; Pagano Zottola AC; Butini S; Gemma S; Casagni A; Laezza C; Vitale M; Ligresti A; Di Marzo V; Zisterer DM; Nathwani S; Williams DC; Campiani G; Gazzerro P; Bifulco M
    Cancer Biol Ther; 2016 Aug; 17(8):849-58. PubMed ID: 26392056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oleanolic acid enhances the radiosensitivity of tumor cells under mimetic hypoxia through the reduction in intracellular GSH content and HIF-1α expression.
    Qi R; Jin W; Wang J; Yi Q; Yu M; Xu S; Jin W
    Oncol Rep; 2014 May; 31(5):2399-406. PubMed ID: 24604140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin.
    Verma NK; Dempsey E; Conroy J; Olwell P; Mcelligott AM; Davies AM; Kelleher D; Butini S; Campiani G; Williams DC; Zisterer DM; Lawler M; Volkov Y
    J Mol Med (Berl); 2008 Apr; 86(4):457-69. PubMed ID: 18270678
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Methoxyestradiol, an endogenous estrogen metabolite, sensitizes radioresistant MCF-7/FIR breast cancer cells through multiple mechanisms.
    Salama S; Diaz-Arrastia C; Patel D; Botting S; Hatch S
    Int J Radiat Oncol Biol Phys; 2011 May; 80(1):231-9. PubMed ID: 21392897
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay.
    Marampon F; Gravina GL; Zani BM; Popov VM; Fratticci A; Cerasani M; Di Genova D; Mancini M; Ciccarelli C; Ficorella C; Di Cesare E; Festuccia C
    Int J Oncol; 2014 Jun; 44(6):2121-31. PubMed ID: 24676782
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ginsenoside Rg3 enhances radiosensitization of hypoxic oesophageal cancer cell lines through vascular endothelial growth factor and hypoxia inducible factor 1α.
    Ge X; Zhen F; Yang B; Yang X; Cai J; Zhang C; Zhang S; Cao Y; Ma J; Cheng H; Sun X
    J Int Med Res; 2014 Jun; 42(3):628-40. PubMed ID: 24691458
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo.
    Greene LM; Fleeton M; Mulligan J; Gowda C; Sheahan BJ; Atkins GJ; Campiani G; Nacci V; Lawler M; Williams DC; Zisterer DM
    Oncol Rep; 2005 Nov; 14(5):1357-63. PubMed ID: 16211309
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.