These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 21135211)

  • 1. Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.
    Han S; Zaniewski RP; Marr ES; Lacey BM; Tomaras AP; Evdokimov A; Miller JR; Shanmugasundaram V
    Proc Natl Acad Sci U S A; 2010 Dec; 107(51):22002-7. PubMed ID: 21135211
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms.
    Sainsbury S; Bird L; Rao V; Shepherd SM; Stuart DI; Hunter WN; Owens RJ; Ren J
    J Mol Biol; 2011 Jan; 405(1):173-84. PubMed ID: 20974151
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural Characterization of Diazabicyclooctane β-Lactam "Enhancers" in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa.
    Rajavel M; Kumar V; Nguyen H; Wyatt J; Marshall SH; Papp-Wallace KM; Deshpande P; Bhavsar S; Yeole R; Bhagwat S; Patel M; Bonomo RA; van den Akker F
    mBio; 2021 Feb; 12(1):. PubMed ID: 33593978
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3.
    Kumar V; Viviani SL; Ismail J; Agarwal S; Bonomo RA; van den Akker F
    PLoS One; 2021; 16(10):e0258359. PubMed ID: 34653211
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinctive attributes of β-lactam target proteins in Acinetobacter baumannii relevant to development of new antibiotics.
    Han S; Caspers N; Zaniewski RP; Lacey BM; Tomaras AP; Feng X; Geoghegan KF; Shanmugasundaram V
    J Am Chem Soc; 2011 Dec; 133(50):20536-45. PubMed ID: 22050378
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of β-Lactam Target-Mediated Resistance.
    Bellini D; Koekemoer L; Newman H; Dowson CG
    J Mol Biol; 2019 Aug; 431(18):3501-3519. PubMed ID: 31301409
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cheminformatics identification of phenolics as modulators of penicillin-binding protein-3 of
    Aribisala JO; Sabiu S
    J Biomol Struct Dyn; 2024; 42(1):298-313. PubMed ID: 36974951
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.
    Murphy-Benenato KE; Dangel B; Davis HE; Durand-Réville TF; Ferguson AD; Gao N; Jahić H; Mueller JP; Manyak EL; Quiroga O; Rooney M; Sha L; Sylvester M; Wu F; Zambrowski M; Zhao SX
    ACS Med Chem Lett; 2015 May; 6(5):537-42. PubMed ID: 26005529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa.
    Mislin GL; Schalk IJ
    Metallomics; 2014 Mar; 6(3):408-20. PubMed ID: 24481292
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Clinically relevant Gram-negative resistance mechanisms have no effect on the efficacy of MC-1, a novel siderophore-conjugated monocarbam.
    McPherson CJ; Aschenbrenner LM; Lacey BM; Fahnoe KC; Lemmon MM; Finegan SM; Tadakamalla B; O'Donnell JP; Mueller JP; Tomaras AP
    Antimicrob Agents Chemother; 2012 Dec; 56(12):6334-42. PubMed ID: 23027195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms.
    Ren J; Nettleship JE; Males A; Stuart DI; Owens RJ
    FEBS Lett; 2016 Jan; 590(2):288-97. PubMed ID: 26823174
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Penicillin-Binding Protein 3 Is Essential for Growth of Pseudomonas aeruginosa.
    Chen W; Zhang YM; Davies C
    Antimicrob Agents Chemother; 2017 Jan; 61(1):. PubMed ID: 27821444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of efficacious Pseudomonas aeruginosa-targeted siderophore-conjugated monocarbams by application of a semi-mechanistic pharmacokinetic/pharmacodynamic model.
    Murphy-Benenato KE; Bhagunde PR; Chen A; Davis HE; Durand-Réville TF; Ehmann DE; Galullo V; Harris JJ; Hatoum-Mokdad H; Jahić H; Kim A; Manjunatha MR; Manyak EL; Mueller J; Patey S; Quiroga O; Rooney M; Sha L; Shapiro AB; Sylvester M; Tan B; Tsai AS; Uria-Nickelsen M; Wu Y; Zambrowski M; Zhao SX
    J Med Chem; 2015 Mar; 58(5):2195-205. PubMed ID: 25658376
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Penicillin-binding protein 3 is a common adaptive target among Pseudomonas aeruginosa isolates from adult cystic fibrosis patients treated with β-lactams.
    Clark ST; Sinha U; Zhang Y; Wang PW; Donaldson SL; Coburn B; Waters VJ; Yau YCW; Tullis DE; Guttman DS; Hwang DM
    Int J Antimicrob Agents; 2019 May; 53(5):620-628. PubMed ID: 30664925
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.
    Goldberg JA; Nguyen H; Kumar V; Spencer EJ; Hoyer D; Marshall EK; Cmolik A; O'Shea M; Marshall SH; Hujer AM; Hujer KM; Rudin SD; Domitrovic TN; Bethel CR; Papp-Wallace KM; Logan LK; Perez F; Jacobs MR; van Duin D; Kreiswirth BM; Bonomo RA; Plummer MS; van den Akker F
    J Med Chem; 2020 Jun; 63(11):5990-6002. PubMed ID: 32420736
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influence of the α-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 β-Lactamase.
    Sacco MD; Kroeck KG; Kemp MT; Zhang X; Andrews LD; Chen Y
    Antimicrob Agents Chemother; 2019 Dec; 64(1):. PubMed ID: 31685462
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria.
    Freischem S; Grimm I; López-Pérez A; Willbold D; Klenke B; Vuong C; Dingley AJ; Weiergräber OH
    Biomolecules; 2021 Jul; 11(7):. PubMed ID: 34356681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
    Bon CG; Grigg JC; Lee J; Robb CS; Caveney NA; Eltis LD; Strynadka NCJ
    J Struct Biol; 2024 Jun; 216(2):108086. PubMed ID: 38527711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Active site restructuring regulates ligand recognition in class A penicillin-binding proteins.
    Macheboeuf P; Di Guilmi AM; Job V; Vernet T; Dideberg O; Dessen A
    Proc Natl Acad Sci U S A; 2005 Jan; 102(3):577-82. PubMed ID: 15637155
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Insights into Ceftobiprole Inhibition of Pseudomonas aeruginosa Penicillin-Binding Protein 3.
    Kumar V; Tang C; Bethel CR; Papp-Wallace KM; Wyatt J; Desarbre E; Bonomo RA; van den Akker F
    Antimicrob Agents Chemother; 2020 Apr; 64(5):. PubMed ID: 32152075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.