BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 21135224)

  • 1. Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment.
    Yudushkin IA; Vale RD
    Proc Natl Acad Sci U S A; 2010 Dec; 107(51):22128-33. PubMed ID: 21135224
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.
    Lysechko TL; Ostergaard HL
    J Immunol; 2005 Jun; 174(12):7807-14. PubMed ID: 15944285
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LAPTM5 promotes lysosomal degradation of intracellular CD3ζ but not of cell surface CD3ζ.
    Kawai Y; Ouchida R; Yamasaki S; Dragone L; Tsubata T; Wang JY
    Immunol Cell Biol; 2014 Jul; 92(6):527-34. PubMed ID: 24638062
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells.
    Dong G; Kalifa R; Nath PR; Babichev Y; Gelkop S; Isakov N
    Cell Signal; 2017 Aug; 36():117-126. PubMed ID: 28465009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The constitutive tyrosine phosphorylation of CD3zeta results from TCR-MHC interactions that are independent of thymic selection.
    Becker AM; DeFord-Watts LM; Wuelfing C; van Oers NS
    J Immunol; 2007 Apr; 178(7):4120-8. PubMed ID: 17371967
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of unique antibodies directed against each of the six different phosphotyrosine residues within the T cell receptor CD3ζ chain.
    Gelkop S; Weisman B; Pulak RN; Zharhary D; Isakov N
    J Immunol Methods; 2012 Jan; 375(1-2):129-37. PubMed ID: 22020291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function.
    Degirmencay A; Thomas S; Holler A; Burgess S; Morris EC; Stauss HJ
    Front Immunol; 2024; 15():1386132. PubMed ID: 38873603
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3ζ chain.
    Dong G; Kalifa R; Nath PR; Gelkop S; Isakov N
    Biochem Biophys Res Commun; 2017 Jul; 488(3):541-546. PubMed ID: 28526413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
    Yamasaki S; Nishida K; Hibi M; Sakuma M; Shiina R; Takeuchi A; Ohnishi H; Hirano T; Saito T
    J Biol Chem; 2001 Nov; 276(48):45175-83. PubMed ID: 11572860
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1.
    Perez-Villar JJ; Whitney GS; Bowen MA; Hewgill DH; Aruffo AA; Kanner SB
    Mol Cell Biol; 1999 Apr; 19(4):2903-12. PubMed ID: 10082557
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism.
    San José E; Borroto A; Niedergang F; Alcover A; Alarcón B
    Immunity; 2000 Feb; 12(2):161-70. PubMed ID: 10714682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quantitative phosphoproteome analysis unveils LAT as a modulator of CD3ζ and ZAP-70 tyrosine phosphorylation.
    Salek M; McGowan S; Trudgian DC; Dushek O; de Wet B; Efstathiou G; Acuto O
    PLoS One; 2013; 8(10):e77423. PubMed ID: 24204825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Obligatory cross-talk with the tyrosine kinases assembled with the TCR/CD3 complex in CD4 signal transduction.
    Ulivieri C; Pacini S; Bartalini S; Valensin S; Telford JL; Baldari CT
    Eur J Immunol; 1999 Aug; 29(8):2625-35. PubMed ID: 10458777
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential T cell receptor-mediated signaling in naive and memory CD4 T cells.
    Farber DL; Acuto O; Bottomly K
    Eur J Immunol; 1997 Aug; 27(8):2094-101. PubMed ID: 9295050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thy-1/CD3 coengagement promotes TCR signaling and enhances particularly tyrosine phosphorylation of the raft molecule LAT.
    Leyton L; Quest AF; Bron C
    Mol Immunol; 1999 Aug; 36(11-12):755-68. PubMed ID: 10593514
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lck mediates signal transmission from CD59 to the TCR/CD3 pathway in Jurkat T cells.
    Lipp AM; Juhasz K; Paar C; Ogris C; Eckerstorfer P; Thuenauer R; Hesse J; Nimmervoll B; Stockinger H; Schütz GJ; Bodenhofer U; Balogi Z; Sonnleitner A
    PLoS One; 2014; 9(1):e85934. PubMed ID: 24454946
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of TCR/CD3 Recycling at the Immune Synapse.
    Patrussi L; Baldari CT
    Methods Mol Biol; 2017; 1584():143-155. PubMed ID: 28255701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.
    Isakov N; Wange RL; Burgess WH; Watts JD; Aebersold R; Samelson LE
    J Exp Med; 1995 Jan; 181(1):375-80. PubMed ID: 7528772
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor.
    Dietrich J; Hou X; Wegener AM; Geisler C
    EMBO J; 1994 May; 13(9):2156-66. PubMed ID: 8187769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. T cells express alpha7-nicotinic acetylcholine receptor subunits that require a functional TCR and leukocyte-specific protein tyrosine kinase for nicotine-induced Ca2+ response.
    Razani-Boroujerdi S; Boyd RT; Dávila-García MI; Nandi JS; Mishra NC; Singh SP; Pena-Philippides JC; Langley R; Sopori ML
    J Immunol; 2007 Sep; 179(5):2889-98. PubMed ID: 17709503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.