BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 21141919)

  • 1. Incorporation of biaryl units into the 5' and 3' ends of sense and antisense strands of siRNA duplexes improves strand selectivity and nuclease resistance.
    Yoshikawa K; Ogata A; Matsuda C; Kohara M; Iba H; Kitade Y; Ueno Y
    Bioconjug Chem; 2011 Jan; 22(1):42-9. PubMed ID: 21141919
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design of nuclease-resistant fork-like small interfering RNA (fsiRNA).
    Chernolovskaya EL; Zenkova MA
    Methods Mol Biol; 2013; 942():153-68. PubMed ID: 23027050
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of nuclease-resistant siRNAs possessing universal overhangs.
    Ueno Y; Watanabe Y; Shibata A; Yoshikawa K; Takano T; Kohara M; Kitade Y
    Bioorg Med Chem; 2009 Mar; 17(5):1974-81. PubMed ID: 19200743
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Influence of assembly of siRNA elements into RNA-induced silencing complex by fork-siRNA duplex carrying nucleotide mismatches at the 3'- or 5'-end of the sense-stranded siRNA element.
    Ohnishi Y; Tokunaga K; Hohjoh H
    Biochem Biophys Res Commun; 2005 Apr; 329(2):516-21. PubMed ID: 15737617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isonucleotide incorporation into middle and terminal siRNA duplexes exhibits high gene silencing efficacy and nuclease resistance.
    Ma Y; Liu S; Wang Y; Zhao Y; Huang Y; Zhong L; Guan Z; Zhang L; Yang Z
    Org Biomol Chem; 2017 Jun; 15(24):5161-5170. PubMed ID: 28585968
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Palmitic acid-conjugated 21-nucleotide siRNA enhances gene-silencing activity.
    Kubo T; Yanagihara K; Takei Y; Mihara K; Morita Y; Seyama T
    Mol Pharm; 2011 Dec; 8(6):2193-203. PubMed ID: 21985606
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications.
    Dande P; Prakash TP; Sioufi N; Gaus H; Jarres R; Berdeja A; Swayze EE; Griffey RH; Bhat B
    J Med Chem; 2006 Mar; 49(5):1624-34. PubMed ID: 16509579
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing activity of 2'-O-methyl modified anti-MDR1 siRNAs with mismatches in the central part of the duplexes.
    Petrova NS; Meschaninova MI; Venyaminova AG; Zenkova MA; Vlassov VV; Chernolovskaya EL
    FEBS Lett; 2011 Jul; 585(14):2352-6. PubMed ID: 21704032
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene-silencing potency of symmetric and asymmetric lipid-conjugated siRNAs and its correlation with dicer recognition.
    Kubo T; Yanagihara K; Sato Y; Nishimura Y; Kondo S; Seyama T
    Bioconjug Chem; 2013 Dec; 24(12):2045-57. PubMed ID: 24274056
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Picking a winner: new mechanistic insights into the design of effective siRNAs.
    Gong D; Ferrell JE
    Trends Biotechnol; 2004 Sep; 22(9):451-4. PubMed ID: 15331225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Asymmetric RNA duplexes mediate RNA interference in mammalian cells.
    Sun X; Rogoff HA; Li CJ
    Nat Biotechnol; 2008 Dec; 26(12):1379-82. PubMed ID: 19029911
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing.
    Bartlett DW; Davis ME
    Biotechnol Bioeng; 2007 Jul; 97(4):909-21. PubMed ID: 17154307
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of siRNAs that contain internal variable-length spacer linkages.
    Efthymiou TC; Peel B; Huynh V; Desaulniers JP
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5590-4. PubMed ID: 22850216
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide.
    Xia J; Noronha A; Toudjarska I; Li F; Akinc A; Braich R; Frank-Kamenetsky M; Rajeev KG; Egli M; Manoharan M
    ACS Chem Biol; 2006 Apr; 1(3):176-83. PubMed ID: 17163665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, gene-silencing activity and nuclease resistance of 3'-3'-linked double short hairpin RNA.
    Masuda H; Watanabe N; Naruoka H; Nagata S; Takagaki K; Wada T; Yano J
    Bioorg Med Chem; 2010 Dec; 18(23):8277-83. PubMed ID: 21051237
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Positional effects and strand preference of RNA interference against hepatitis C virus target sequences.
    Smith RM; Smolic R; Volarevic M; Wu GY
    J Viral Hepat; 2007 Mar; 14(3):194-212. PubMed ID: 17305886
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancement of stability and activity of siRNA by terminal substitution with serinol nucleic acid (SNA).
    Kamiya Y; Takai J; Ito H; Murayama K; Kashida H; Asanuma H
    Chembiochem; 2014 Nov; 15(17):2549-55. PubMed ID: 25233814
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interfering with hepatitis C virus RNA replication.
    Randall G; Rice CM
    Virus Res; 2004 Jun; 102(1):19-25. PubMed ID: 15068876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective protection of nuclease-sensitive sites in siRNA prolongs silencing effect.
    Volkov AA; Kruglova NS; Meschaninova MI; Venyaminova AG; Zenkova MA; Vlassov VV; Chernolovskaya EL
    Oligonucleotides; 2009 Jun; 19(2):191-202. PubMed ID: 19344210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RNA interference induced by siRNAs modified with 4'-thioribonucleosides in cultured mammalian cells.
    Hoshika S; Minakawa N; Kamiya H; Harashima H; Matsuda A
    FEBS Lett; 2005 Jun; 579(14):3115-8. PubMed ID: 15919084
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.