These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 21142217)

  • 1. Design of new chemotherapeutics against the deadly anthrax disease. Docking and molecular dynamics studies of inhibitors containing pyrrolidine and riboamidrazone rings on nucleoside hydrolase from Bacillus anthracis.
    Guimarães AP; Oliveira AA; da Cunha EF; Ramalho TC; França TC
    J Biomol Struct Dyn; 2011 Feb; 28(4):455-69. PubMed ID: 21142217
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined virtual screening, MMPBSA, molecular docking and dynamics studies against deadly anthrax: An in silico effort to inhibit Bacillus anthracis nucleoside hydrolase.
    Karami M; Jalali C; Mirzaie S
    J Theor Biol; 2017 May; 420():180-189. PubMed ID: 28300596
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular modeling studies on nucleoside hydrolase from the biological warfare agent Brucella suis.
    Mancini DT; Matos KS; da Cunha EF; Assis TM; Guimarães AP; França TC; Ramalho TC
    J Biomol Struct Dyn; 2012; 30(1):125-36. PubMed ID: 22571438
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of Bacillus anthracis nucleoside hydrolase via in silico docking with inhibitors and molecular dynamics simulation.
    Guimarães AP; Oliveira AA; da Cunha EF; Ramalho TC; França TC
    J Mol Model; 2011 Nov; 17(11):2939-51. PubMed ID: 21318235
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
    Versées W; Decanniere K; Pellé R; Depoorter J; Brosens E; Parkin DW; Steyaert J
    J Mol Biol; 2001 Apr; 307(5):1363-79. PubMed ID: 11292348
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.
    Versées W; Barlow J; Steyaert J
    J Mol Biol; 2006 Jun; 359(2):331-46. PubMed ID: 16630632
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.
    Goeminne A; Berg M; McNaughton M; Bal G; Surpateanu G; Van der Veken P; De Prol S; Versées W; Steyaert J; Haemers A; Augustyns K
    Bioorg Med Chem; 2008 Jul; 16(14):6752-63. PubMed ID: 18571422
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modeling toward selective inhibitors of dihydrofolate reductase from the biological warfare agent Bacillus anthracis.
    Giacoppo JO; Mancini DT; Guimarães AP; Gonçalves AS; da Cunha EF; França TC; Ramalho TC
    Eur J Med Chem; 2015 Feb; 91():63-71. PubMed ID: 24985033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors.
    Goeminne A; McNaughton M; Bal G; Surpateanu G; Van Der Veken P; De Prol S; Versées W; Steyaert J; Haemers A; Augustyns K
    Eur J Med Chem; 2008 Feb; 43(2):315-26. PubMed ID: 17582660
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis.
    Porter CJ; Schuch R; Pelzek AJ; Buckle AM; McGowan S; Wilce MC; Rossjohn J; Russell R; Nelson D; Fischetti VA; Whisstock JC
    J Mol Biol; 2007 Feb; 366(2):540-50. PubMed ID: 17182056
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Computational study of IAG-nucleoside hydrolase: determination of the preferred ground state conformation and the role of active site residues.
    Mazumder-Shivakumar D; Bruice TC
    Biochemistry; 2005 May; 44(21):7805-17. PubMed ID: 15909995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. QM/MM molecular dynamics study of purine-specific nucleoside hydrolase.
    Wu R; Gong W; Liu T; Zhang Y; Cao Z
    J Phys Chem B; 2012 Feb; 116(6):1984-91. PubMed ID: 22257300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase.
    Bennett BC; Xu H; Simmerman RF; Lee RE; Dealwis CG
    J Med Chem; 2007 Sep; 50(18):4374-81. PubMed ID: 17696333
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the catalytic activity of the gamma-phage lysin, PlyG, specific for Bacillus anthracis.
    Kikkawa HS; Ueda T; Suzuki S; Yasuda J
    FEMS Microbiol Lett; 2008 Sep; 286(2):236-40. PubMed ID: 18662316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.
    Versées W; Goeminne A; Berg M; Vandemeulebroucke A; Haemers A; Augustyns K; Steyaert J
    Biochim Biophys Acta; 2009 Jun; 1794(6):953-60. PubMed ID: 19281874
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design.
    Babaoglu K; Qi J; Lee RE; White SW
    Structure; 2004 Sep; 12(9):1705-17. PubMed ID: 15341734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A bacteriolytic agent that detects and kills Bacillus anthracis.
    Schuch R; Nelson D; Fischetti VA
    Nature; 2002 Aug; 418(6900):884-9. PubMed ID: 12192412
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis.
    Byun Y; Vogel SR; Phipps AJ; Carnrot C; Eriksson S; Tiwari R; Tjarks W
    Nucleosides Nucleotides Nucleic Acids; 2008 Mar; 27(3):244-60. PubMed ID: 18260009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homology modeling, docking and molecular dynamics of the Leishmania mexicana arginase: a description of the catalytic site useful for drug design.
    Méndez-Cuesta CA; Méndez-Lucio O; Castillo R
    J Mol Graph Model; 2012 Sep; 38():50-9. PubMed ID: 23085157
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular dynamics simulations of complexes between wild-type and mutant anthrax protective antigen variants and a model anthrax toxin receptor.
    Stiles L; Nelson DJ
    J Biomol Struct Dyn; 2005 Apr; 22(5):503-19. PubMed ID: 15702923
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.