BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 21145396)

  • 1. Proteasomal dysfunction in aging and Huntington disease.
    Li XJ; Li S
    Neurobiol Dis; 2011 Jul; 43(1):4-8. PubMed ID: 21145396
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons.
    Tydlacka S; Wang CE; Wang X; Li S; Li XJ
    J Neurosci; 2008 Dec; 28(49):13285-95. PubMed ID: 19052220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments.
    Li X; Wang CE; Huang S; Xu X; Li XJ; Li H; Li S
    Hum Mol Genet; 2010 Jun; 19(12):2445-55. PubMed ID: 20354076
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clearance of mutant huntingtin.
    Li XJ; Li H; Li S
    Autophagy; 2010 Jul; 6(5):663-4. PubMed ID: 20519964
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein turnover and inclusion body formation.
    Mitra S; Tsvetkov AS; Finkbeiner S
    Autophagy; 2009 Oct; 5(7):1037-8. PubMed ID: 19838079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease.
    Mitra S; Tsvetkov AS; Finkbeiner S
    J Biol Chem; 2009 Feb; 284(7):4398-403. PubMed ID: 19074152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease.
    Liu Y; Hettinger CL; Zhang D; Rezvani K; Wang X; Wang H
    J Neurochem; 2014 May; 129(3):539-47. PubMed ID: 24383989
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteasome activator enhances survival of Huntington's disease neuronal model cells.
    Seo H; Sonntag KC; Kim W; Cattaneo E; Isacson O
    PLoS One; 2007 Feb; 2(2):e238. PubMed ID: 17327906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice.
    Wang J; Wang CE; Orr A; Tydlacka S; Li SH; Li XJ
    J Cell Biol; 2008 Mar; 180(6):1177-89. PubMed ID: 18362179
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ubiquitin-proteasome reporter GFPu does not accumulate in neurons of the R6/2 transgenic mouse model of Huntington's disease.
    Bett JS; Cook C; Petrucelli L; Bates GP
    PLoS One; 2009; 4(4):e5128. PubMed ID: 19352500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Testing the possible inhibition of proteasome by direct interaction with ubiquitylated and aggregated huntingtin.
    Valera AG; Díaz-Hernández M; Hernández F; Lucas JJ
    Brain Res Bull; 2007 Apr; 72(2-3):121-3. PubMed ID: 17352935
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.
    Zhao T; Hong Y; Li S; Li XJ
    J Neurosci; 2016 Aug; 36(32):8317-28. PubMed ID: 27511006
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
    Ciechanover A; Kwon YT
    Exp Mol Med; 2015 Mar; 47(3):e147. PubMed ID: 25766616
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
    Jana NR; Zemskov EA; Wang Gh ; Nukina N
    Hum Mol Genet; 2001 May; 10(10):1049-59. PubMed ID: 11331615
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein aggregation and neurodegeneration: clues from a yeast model of Huntington's disease.
    Bocharova N; Chave-Cox R; Sokolov S; Knorre D; Severin F
    Biochemistry (Mosc); 2009 Feb; 74(2):231-4. PubMed ID: 19267681
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Differential Profiling of Ubiquitin-Proteasome and Autophagy Systems in Different Tissues before the Onset of Huntington's Disease Models.
    Her LS; Lin JY; Fu MH; Chang YF; Li CL; Tang TY; Jhang YL; Chang CY; Shih MC; Cheng PH; Yang SH
    Brain Pathol; 2015 Jul; 25(4):481-90. PubMed ID: 25178567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones.
    Rousseau E; Kojima R; Hoffner G; Djian P; Bertolotti A
    J Biol Chem; 2009 Jan; 284(3):1917-29. PubMed ID: 18986984
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Compensatory changes in the ubiquitin-proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients.
    Seo H; Kim W; Isacson O
    Hum Mol Genet; 2008 Oct; 17(20):3144-53. PubMed ID: 18640989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease.
    Hunter JM; Lesort M; Johnson GV
    J Neurosci Res; 2007 Jun; 85(8):1774-88. PubMed ID: 17455294
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
    Luo H; Cao L; Liang X; Du A; Peng T; Li H
    Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.