BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 21147256)

  • 1. The reconstructed skin micronucleus assay (RSMN) in EpiDerm™: detailed protocol and harmonized scoring atlas.
    Dahl EL; Curren R; Barnett BC; Khambatta Z; Reisinger K; Ouedraogo G; Faquet B; Ginestet AC; Mun G; Hewitt NJ; Carr G; Pfuhler S; Aardema MJ
    Mutat Res; 2011 Feb; 720(1-2):42-52. PubMed ID: 21147256
    [TBL] [Abstract][Full Text] [Related]  

  • 2. International prevalidation studies of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay: transferability and reproducibility.
    Aardema MJ; Barnett BC; Khambatta Z; Reisinger K; Ouedraogo-Arras G; Faquet B; Ginestet AC; Mun GC; Dahl EL; Hewitt NJ; Corvi R; Curren RD
    Mutat Res; 2010 Aug; 701(2):123-31. PubMed ID: 20621637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intralaboratory and interlaboratory evaluation of the EpiDerm 3D human reconstructed skin micronucleus (RSMN) assay.
    Hu T; Kaluzhny Y; Mun GC; Barnett B; Karetsky V; Wilt N; Klausner M; Curren RD; Aardema MJ
    Mutat Res; 2009 Mar; 673(2):100-8. PubMed ID: 19167513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of chemicals requiring metabolic activation in the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay.
    Aardema MJ; Barnett BB; Mun GC; Dahl EL; Curren RD; Hewitt NJ; Pfuhler S
    Mutat Res; 2013 Jan; 750(1-2):40-9. PubMed ID: 23022594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Further development of the EpiDerm 3D reconstructed human skin micronucleus (RSMN) assay.
    Mun GC; Aardema MJ; Hu T; Barnett B; Kaluzhny Y; Klausner M; Karetsky V; Dahl EL; Curren RD
    Mutat Res; 2009 Mar; 673(2):92-9. PubMed ID: 19167515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays.
    Pfuhler S; Downs TR; Hewitt NJ; Hoffmann S; Mun GC; Ouedraogo G; Roy S; Curren RD; Aardema MJ
    Mutagenesis; 2021 Apr; 36(1):1-17. PubMed ID: 33544138
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of genotoxicity test procedures with Episkin, a reconstructed human skin model: towards new tools for in vitro risk assessment of dermally applied compounds?
    Flamand N; Marrot L; Belaidi JP; Bourouf L; Dourille E; Feltes M; Meunier JR
    Mutat Res; 2006 Jul; 606(1-2):39-51. PubMed ID: 16675293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of the genotoxic compounds, benzo[a]pyrene and cyclophosphamide on phase 1 and 2 activities in EpiDerm™ models.
    Götz C; Hewitt NJ; Jermann E; Tigges J; Kohne Z; Hübenthal U; Krutmann J; Merk HF; Fritsche E
    Xenobiotica; 2012 Jun; 42(6):526-37. PubMed ID: 22175647
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Historical control data and proof of principle studies for mechanistic assay adaptations.
    Roy S; Kulkarni R; Hewitt NJ; Aardema MJ
    Mutat Res Genet Toxicol Environ Mutagen; 2016 Jul; 805():25-37. PubMed ID: 27402480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses.
    Chapman KE; Thomas AD; Wills JW; Pfuhler S; Doak SH; Jenkins GJ
    Mutagenesis; 2014 May; 29(3):165-75. PubMed ID: 24675152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The reconstructed skin micronucleus assay in EpiDerm™: reduction of false-positive results - a mechanistic study with epigallocatechin gallate.
    Yuki K; Ikeda N; Nishiyama N; Kasamatsu T
    Mutat Res Genet Toxicol Environ Mutagen; 2013 Oct; 757(2):148-57. PubMed ID: 23988588
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.
    Reisinger K; Blatz V; Brinkmann J; Downs TR; Fischer A; Henkler F; Hoffmann S; Krul C; Liebsch M; Luch A; Pirow R; Reus AA; Schulz M; Pfuhler S
    Mutat Res Genet Toxicol Environ Mutagen; 2018 Mar; 827():27-41. PubMed ID: 29502735
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The 3D reconstructed skin micronucleus assay: considerations for optimal protocol design.
    Kidd D; Phillips S; Chirom T; Mason N; Smith R; Saul J; Whitwell J; Clements J
    Mutagenesis; 2021 Apr; 36(1):37-49. PubMed ID: 31793640
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei.
    Bonassi S; Fenech M; Lando C; Lin YP; Ceppi M; Chang WP; Holland N; Kirsch-Volders M; Zeiger E; Ban S; Barale R; Bigatti MP; Bolognesi C; Jia C; Di Giorgio M; Ferguson LR; Fucic A; Lima OG; Hrelia P; Krishnaja AP; Lee TK; Migliore L; Mikhalevich L; Mirkova E; Mosesso P; Müller WU; Odagiri Y; Scarffi MR; Szabova E; Vorobtsova I; Vral A; Zijno A
    Environ Mol Mutagen; 2001; 37(1):31-45. PubMed ID: 11170240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.
    Hayashi M; MacGregor JT; Gatehouse DG; Blakey DH; Dertinger SD; Abramsson-Zetterberg L; Krishna G; Morita T; Russo A; Asano N; Suzuki H; Ohyama W; Gibson D;
    Mutat Res; 2007 Feb; 627(1):10-30. PubMed ID: 17157053
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Use of the EpiDermTM 3D reconstructed skin micronucleus assay for fragrance materials.
    Thakkar Y; Moustakas H; Aardema M; Roy S; Pfuhler S; Api AM
    Mutagenesis; 2022 May; 37(2):89-111. PubMed ID: 34850913
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps.
    Holland N; Bolognesi C; Kirsch-Volders M; Bonassi S; Zeiger E; Knasmueller S; Fenech M
    Mutat Res; 2008; 659(1-2):93-108. PubMed ID: 18514568
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Validation of in vitro Tests for Skin Corrosivity.
    Fentem JH
    ALTEX; 1999; 16(3):150-153. PubMed ID: 11107323
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on In Vitro Mammalian Cell Micronucleus Test.
    Cariou O; Laroche-Prigent N; Ledieu S; Guizon I; Paillard F; Thybaud V
    Mutat Res; 2010 Oct; 702(2):148-56. PubMed ID: 20398790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation.
    Allemang A; Thacker R; DeMarco RA; Rodrigues MA; Pfuhler S
    Mutat Res Genet Toxicol Environ Mutagen; 2021 May; 865():503314. PubMed ID: 33865536
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.