BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 21147768)

  • 1. Ligand migration in the apolar tunnel of Cerebratulus lacteus mini-hemoglobin.
    Pesce A; Nardini M; Dewilde S; Capece L; Martí MA; Congia S; Salter MD; Blouin GC; Estrin DA; Ascenzi P; Moens L; Bolognesi M; Olson JS
    J Biol Chem; 2011 Feb; 286(7):5347-58. PubMed ID: 21147768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The apolar channel in Cerebratulus lacteus hemoglobin is the route for O2 entry and exit.
    Salter MD; Nienhaus K; Nienhaus GU; Dewilde S; Moens L; Pesce A; Nardini M; Bolognesi M; Olson JS
    J Biol Chem; 2008 Dec; 283(51):35689-702. PubMed ID: 18840607
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transient ligand docking sites in Cerebratulus lacteus mini-hemoglobin.
    Deng P; Nienhaus K; Palladino P; Olson JS; Blouin G; Moens L; Dewilde S; Geuens E; Nienhaus GU
    Gene; 2007 Aug; 398(1-2):208-23. PubMed ID: 17531406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determination of ligand pathways in globins: apolar tunnels versus polar gates.
    Salter MD; Blouin GC; Soman J; Singleton EW; Dewilde S; Moens L; Pesce A; Nardini M; Bolognesi M; Olson JS
    J Biol Chem; 2012 Sep; 287(40):33163-78. PubMed ID: 22859299
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High resolution crystal structures of the Cerebratulus lacteus mini-Hb in the unligated and carbomonoxy states.
    Germani F; Pesce A; Venturini A; Moens L; Bolognesi M; Dewilde S; Nardini M
    Int J Mol Sci; 2012; 13(7):8025-8037. PubMed ID: 22942687
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thr-E11 regulates O2 affinity in Cerebratulus lacteus mini-hemoglobin.
    Pesce A; Nardini M; Ascenzi P; Geuens E; Dewilde S; Moens L; Bolognesi M; Riggs AF; Hale A; Deng P; Nienhaus GU; Olson JS; Nienhaus K
    J Biol Chem; 2004 Aug; 279(32):33662-72. PubMed ID: 15161908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities.
    Dantsker D; Roche C; Samuni U; Blouin G; Olson JS; Friedman JM
    J Biol Chem; 2005 Nov; 280(46):38740-55. PubMed ID: 16155005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distal histidine stabilizes bound O2 and acts as a gate for ligand entry in both subunits of adult human hemoglobin.
    Birukou I; Schweers RL; Olson JS
    J Biol Chem; 2010 Mar; 285(12):8840-54. PubMed ID: 20080971
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The 109 residue nerve tissue minihemoglobin from Cerebratulus lacteus highlights striking structural plasticity of the alpha-helical globin fold.
    Pesce A; Nardini M; Dewilde S; Geuens E; Yamauchi K; Ascenzi P; Riggs AF; Moens L; Bolognesi M
    Structure; 2002 May; 10(5):725-35. PubMed ID: 12015154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulating distal cavities in the α and β subunits of human HbA reveals the primary ligand migration pathway.
    Birukou I; Maillett DH; Birukova A; Olson JS
    Biochemistry; 2011 Aug; 50(34):7361-74. PubMed ID: 21793487
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two distinct heme distal site states define Cerebratulus lacteus mini-hemoglobin oxygen affinity.
    Martí MA; Bikiel DE; Crespo A; Nardini M; Bolognesi M; Estrin DA
    Proteins; 2006 Mar; 62(3):641-8. PubMed ID: 16432879
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of the kinetic barriers for ligand binding to sperm whale myoglobin using site-directed mutagenesis and laser photolysis techniques.
    Carver TE; Rohlfs RJ; Olson JS; Gibson QH; Blackmore RS; Springer BA; Sligar SG
    J Biol Chem; 1990 Nov; 265(32):20007-20. PubMed ID: 2246277
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mapping protein matrix cavities in human cytoglobin through Xe atom binding.
    de Sanctis D; Dewilde S; Pesce A; Moens L; Ascenzi P; Hankeln T; Burmester T; Bolognesi M
    Biochem Biophys Res Commun; 2004 Apr; 316(4):1217-21. PubMed ID: 15044115
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis.
    Dantsker D; Samuni U; Ouellet Y; Wittenberg BA; Wittenberg JB; Milani M; Bolognesi M; Guertin M; Friedman JM
    J Biol Chem; 2004 Sep; 279(37):38844-53. PubMed ID: 15234986
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heme-ligand tunneling in group I truncated hemoglobins.
    Milani M; Pesce A; Ouellet Y; Dewilde S; Friedman J; Ascenzi P; Guertin M; Bolognesi M
    J Biol Chem; 2004 May; 279(20):21520-5. PubMed ID: 15016811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ligand migration in the truncated hemoglobin-II from Mycobacterium tuberculosis: the role of G8 tryptophan.
    Guallar V; Lu C; Borrelli K; Egawa T; Yeh SR
    J Biol Chem; 2009 Jan; 284(5):3106-3116. PubMed ID: 19019831
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular oxygen migration through the xenon docking sites of human hemoglobin in the R-state.
    Lepeshkevich SV; Gilevich SN; Parkhats MV; Dzhagarov BM
    Biochim Biophys Acta; 2016 Sep; 1864(9):1110-1121. PubMed ID: 27288155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Internal cavities and ligand passageways in human hemoglobin characterized by molecular dynamics simulations.
    Mouawad L; Maréchal JD; Perahia D
    Biochim Biophys Acta; 2005 Aug; 1724(3):385-93. PubMed ID: 15963643
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water.
    Ouellet YH; Daigle R; Lagüe P; Dantsker D; Milani M; Bolognesi M; Friedman JM; Guertin M
    J Biol Chem; 2008 Oct; 283(40):27270-8. PubMed ID: 18676995
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effects of E7 and E11 mutations on the kinetics of ligand binding to R state human hemoglobin.
    Mathews AJ; Rohlfs RJ; Olson JS; Tame J; Renaud JP; Nagai K
    J Biol Chem; 1989 Oct; 264(28):16573-83. PubMed ID: 2777799
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.