BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 21148293)

  • 1. The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508.
    Grove DE; Fan CY; Ren HY; Cyr DM
    Mol Biol Cell; 2011 Feb; 22(3):301-14. PubMed ID: 21148293
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy.
    He L; Kennedy AS; Houck S; Aleksandrov A; Quinney NL; Cyr-Scully A; Cholon DM; Gentzsch M; Randell SH; Ren HY; Cyr DM
    Mol Biol Cell; 2021 Apr; 32(7):538-553. PubMed ID: 33534640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase.
    Younger JM; Ren HY; Chen L; Fan CY; Fields A; Patterson C; Cyr DM
    J Cell Biol; 2004 Dec; 167(6):1075-85. PubMed ID: 15611333
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.
    Younger JM; Chen L; Ren HY; Rosser MF; Turnbull EL; Fan CY; Patterson C; Cyr DM
    Cell; 2006 Aug; 126(3):571-82. PubMed ID: 16901789
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms for rescue of correctable folding defects in CFTRDelta F508.
    Grove DE; Rosser MF; Ren HY; Naren AP; Cyr DM
    Mol Biol Cell; 2009 Sep; 20(18):4059-69. PubMed ID: 19625452
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.
    Morito D; Hirao K; Oda Y; Hosokawa N; Tokunaga F; Cyr DM; Tanaka K; Iwai K; Nagata K
    Mol Biol Cell; 2008 Apr; 19(4):1328-36. PubMed ID: 18216283
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hsp70 and DNAJA2 limit CFTR levels through degradation.
    Kim Chiaw P; Hantouche C; Wong MJH; Matthes E; Robert R; Hanrahan JW; Shrier A; Young JC
    PLoS One; 2019; 14(8):e0220984. PubMed ID: 31408507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR.
    Yamamoto YH; Kimura T; Momohara S; Takeuchi M; Tani T; Kimata Y; Kadokura H; Kohno K
    Cell Struct Funct; 2010; 35(2):107-16. PubMed ID: 21150129
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cysteine string protein promotes proteasomal degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) by increasing its interaction with the C terminus of Hsp70-interacting protein and promoting CFTR ubiquitylation.
    Schmidt BZ; Watts RJ; Aridor M; Frizzell RA
    J Biol Chem; 2009 Feb; 284(7):4168-78. PubMed ID: 19098309
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel mammalian ER-located J-protein, DNAJB14, can accelerate ERAD of misfolded membrane proteins.
    Sopha P; Kadokura H; Yamamoto YH; Takeuchi M; Saito M; Tsuru A; Kohno K
    Cell Struct Funct; 2012; 37(2):177-87. PubMed ID: 23018488
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR.
    Baaklini I; Gonçalves CC; Lukacs GL; Young JC
    Sci Rep; 2020 Mar; 10(1):4176. PubMed ID: 32144307
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation.
    Meacham GC; Patterson C; Zhang W; Younger JM; Cyr DM
    Nat Cell Biol; 2001 Jan; 3(1):100-5. PubMed ID: 11146634
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR).
    El Khouri E; Le Pavec G; Toledano MB; Delaunay-Moisan A
    J Biol Chem; 2013 Oct; 288(43):31177-91. PubMed ID: 24019521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels.
    Saxena A; Banasavadi-Siddegowda YK; Fan Y; Bhattacharya S; Roy G; Giovannucci DR; Frizzell RA; Wang X
    J Biol Chem; 2012 Jun; 287(23):19158-70. PubMed ID: 22505710
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligase.
    Matsumura Y; Sakai J; Skach WR
    J Biol Chem; 2013 Oct; 288(43):31069-79. PubMed ID: 23990462
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of CFTR folding and degradation in transiently transfected cells.
    Grove DE; Rosser MF; Watkins RL; Cyr DM
    Methods Mol Biol; 2011; 741():219-32. PubMed ID: 21594788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70.
    Farinha CM; Nogueira P; Mendes F; Penque D; Amaral MD
    Biochem J; 2002 Sep; 366(Pt 3):797-806. PubMed ID: 12069690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dissection of the Role of VIMP in Endoplasmic Reticulum-Associated Degradation of CFTRΔF508.
    Hou X; Wei H; Rajagopalan C; Jiang H; Wu Q; Zaman K; Xie Y; Sun F
    Sci Rep; 2018 Mar; 8(1):4764. PubMed ID: 29555962
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis.
    Sopha P; Ren HY; Grove DE; Cyr DM
    J Biol Chem; 2017 Jul; 292(28):11792-11803. PubMed ID: 28536268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assembly and misassembly of cystic fibrosis transmembrane conductance regulator: folding defects caused by deletion of F508 occur before and after the calnexin-dependent association of membrane spanning domain (MSD) 1 and MSD2.
    Rosser MF; Grove DE; Chen L; Cyr DM
    Mol Biol Cell; 2008 Nov; 19(11):4570-9. PubMed ID: 18716059
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.